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344 Cards in this Set

  • Front
  • Back
What type of disease is RA?
Inflammatory/autoimmune
what is the most common chronic inflammatory arthritide?
RA
what percentage of the pop is affected by RA?
1%- gen pop
2%- of the pop over 60 yrs old
what are the criteria for diagnosing RA?
must have at least 4...
1.stiff in the morning (at least 1 hr) jelling phenomenon
2. swelling (3+ joints)
3. swelling (wrist, pip, mcp)
4. swelling (symmetric)
5. Rheumatoid nodules
6. Pos Rheumatoid factor test
7. Radiographic changes
`
what anatomical structure does RA affect?
synovial lining
inflammatory enthesopathy
synovial lining of tendon sheaths and burasae
What are the positive lab findings for RA?
1.+ RA factor (sheep. agglutination test)
2. decreased mucin precipitate (synovial fluid)
3. synovium - villous hypertrophy, superficial synovial cell proliferation, marked inflammatory cell infiltrate fibrin deposition, foci of cell necrosis
4. nodules - granulomas with central necrosis, proliferated fixed cells, peripheral fibrosis, chronic inflammatory cell infiltrate.
5. uniform joint space loss, marginal erosions
what is the classical distribution of RA?
Bilateral and symmetrical
typical Age of onset for RA?
20-60 yrs
peak onset - 40-50yrs
RA - most commmon in women or men?
women - 3:1
Classic place of distribution?
Hands and feet - PIPs, MCP, wrists (proximal)
when the SI joint is affected by RA is it most commonly affected unilaterally or bilaterally?
unilaterally
define jelling phenomenon.
a stiffness w/inactivity or disuse
starts w/ PIPs and moves proximally
what percentage of pts with RA in hands will also dev changes in their cervical spine?
80%
what percentage of pts dev rheumatoid nodules?
20% - extensor surfaces, non-tender
what are Haygarths nodes?
swelling of the MCP joints
4 clinical findings assoc with RA?
Raynauds phenomenon
tendon rupture
pannus formation
sjogrens syndrome
What is sjogrens syndrome?
keratoconjunctivitis sicca (dry eyes)
xerostomia (dry mouth)
RA
what type of anemia is assoc with RA?
normochromic , normocytic
how does RA affect the leukocyte count?
normal or increased
what does RA do to the ESR and c-reactive protein levels?
increases
what percentage of pts with RA have RA factor?
70%
what is a Pannus?
granulation tissue and inflamed synovium
what forms around the pannus?
marginal erosions
what is the first radiographic sign of RA?
periarticular soft tissue swelling
what are the radiographic findings of RA?
1. periarticular soft tissue swellign
2. juxtaarticular osteoperosis
3. uniform loss of joint space
4. marginal "rat bite" erosions
5. juxta-articular periostitis
6. large pseudocysts
7. deformities
what is the earliest sign of RA?
soft tissue swelling around the joint
what is the earliest joint alteration of RA?
marginal erosions - 2nd and 3rd met heads and the PIPs. (radial side)
what deformities are associated with RA?
Swan neck- flex dip, ext PIP
Boutoniere- flex PIP, ext DIP
ulnar deviation
what is usually the first site of wrist involvment for RA?
distal ulna
In RA, erosion of the lateral ulna styloid is caused by what?
extensor carpi ulnaris
what is the spotty carpal sign associated with RA?
multiple erosions of carpals
what other conditions also have the spotty carpal sign?
CPPD, infections, PA, Gout
What is the zig zag sign assoc with RA?
Radial deviation of the proximal row with ulnar deviation of the fingers
what is the terry thomas sign assoc with RA?
scapholunate dislocation
what is the m/c site of erosions in the foot b/c of RA?
5th MTP - lateral side
all other erosions - medial side
what is the lanois deformity assoc with RA?
fibular deviations and dorsal subluxations of the MTP jts
what is the m/c migration of the femoral head in RA?
axial migration
m/c bilateral protrusio acetabulae
what joints in the shoulder are m/c affected by RA?
Glenohumoral
A/C
which way does the humorous m/c migrate?
superior
what percentage of RA pts have an abnormal fat pad?
90%
what are fad pads caused by?
intraarticular efusion (swelling in the joint)
in the knee RA causes a large posterior soft tissue mass called?
bakers cyst
location of m/c involvement of foot joints ?
tarsal and mortise jt/s (eventually ankyloses)
what are the radiographic signs d/t RA in the cervical spine?
dens ersosions
widened ADI - 3mm - adults
- 5 mm kids
subluxations below cervical level
facet erosions
loss of disc space (pannus)
what radiographic changes are seen on the occiput/c1 with RA?
atlas collapse
dens protrudes into foramen magnum (causes basilar invagination)
ankylosis
neck shortens w/ dens invagination
what causes instability in the c1/c2 area with RA?
ligamentous laxity/disruption
increased ADI
what is the name for erosions on the dens?
whittleing of the dens
what deformity gives the vertebra a sharpened pencil appearance?
erosion of the spinous process
what happens to the vertebra to give them a step ladder appearance ?
anterior displacements of the vertebra
what conditions are considered juvenile rheumatoid arthritis ?
PA, JRA, AS, all prior to 16yrs old
what inflammatory conditions are considered Juvenile chronic arthritis?
PA, AS, JRA , prior to 16 yrs old
what makes an inflammatory condition seropositive?
presence of RA factor
what percentage of JRA types are seropositive?
10% - poorest prognosis
what RA diseases are considered seronegative?
classic systemic disease (20%)
polyarticular diesease
pauciarticular/monoarticular
stills
what signs and symptoms are associated with classic systemic disease?
 High, acute, intermittent fever
 Lymphadenopathy
 Hepatosplenomnegaly
 Polyserositis
 Carditis
 Leukocytosis

what is the m/c form of JRA?
polyarticular disease - 50%
does polyarticular disease affect males or females more?
females 2:1
what is the most common form of seronegative JCA to demostrate definite radiographic changes?
pauciarticular disease
how many joints are involved in pauciarticular/monoarticular disease?
4 or fewer
what percentage of JRA patients develop pauciarticular/monoarticular disease?
30%
patients with pauciarticular/monoarticular disease also may develop iridocyclitis . what is iridocyclitis?
inflammation of the iris and ciliary body that can cause you to go blind
what are pathological changes associated with JCA?
inflammation of the synovium
bony ankylosis (RA is fibrous ankylosis)
Growth disturbances
what are radiological features associated with JCA?
soft tissue swelling
periostitis
osteoperosis
articular erosions
ballooning (metaphyseal overgrowth)
bony ankylosis
fusion of growth plates
uniform loss of joint space
what is the main target of JCA?
hands and feet (spares the DIPS)
In JCA where is ankylosing m/c seen?
wrist - mid and hind
foot
IP joints
what disease is the tibiotalar slant deformity seen?
JRA
what pathological changes are seen in the knee with JCA/JRA?
Squaring” of the inf pole of the patella
Widening of the intercondylar notch
Ballooning of the epiphysis
what is the m/c c/s level affected by JRA/JCA?
C1-C4
what c/s levels are most affected by ankylosing of the facets d/t JRA/JCA?
C2-C4
aka for ankylosing spondylitis?
marie strumpells disease
define avulsion fracture.
a fracture at the attachment of a ligament or tendon pulled from the parent bone
define comminuted fracture.
two or more fractures/ fragments/line - result of greater force or more rapid application. butterfly, wedge shaped fragment in shaft or long bone at apex or injury
define diastatic fractures
separation injury of synarthrodial joint
define occult fracture
fracture with out radiographic evidence . re-exame 10-14 days to better visualize the fracture line
what is the m/c area affected by a salter-harris fracture?
radial epiphysis
what is a type 1 salter harris fracture?
isolated injury through physis (growth plate)
what is a type 2 salter-harris fracture?
fracture through physis to metaphysis - small metaphyseal portion = thurston holland
what is a type 3 salter harris fracture?
through physis into epiphysis - m/c distal tibia . intra-articular and secondary changes may result from the injury
what is a type 4 salter harris fracture?
fracture extends through all 3 layers. metaphysis , physis, epiphysis. oblique or spinal fractures . m/c lateral condyle of humerous
what is a type 5 salter harris fracture?
compression injury to physis with no associated fracture to the epiphysis or metaphysis. looks normal on x-ray
what are two types of impaction fractures?
depression
compression
describe what a depression fracture is.
one bone is driven into the adjacent bone
what is a compression fracture?
articular surfaces of bone approximate on one another
what are two types of stress fractures?
fatigue fx
insufficiency fx
what is the difference between a fatigue fx and a insufficiency fx?
fatigue - d/t abnormal stress (repeated)
insufficiency - d/t normal stress (repeated)
define - aviator fx
compression fx of the talar neck
define barroom fx
transverse fx of neck of 4th and 5th metacarpal
define bartons fx
RIM fx. interarticular fx of the posterior rim of distal radius
define a bedroom fx
fx of phalanx in foot (bed post)
define bennetts fx
fx-dislocation , intra-articular fx of metacarpal base with dorsal radial displacement of the shaft
define a boxer fx
transverse fracture of neck of the 2nd and 3rd metacarpal neck
define a bucket-handel fx
superior dislocation and fx of the posterior acetabular rim
define bumper fx
compound fx of lateral tibial plateau caused by valgus force
define a chance fx
aka seat belt fx, fulcom fx, transverse fx, through the spinous process and neural arch that extends into and possibly through the vertebral body
define chauffeurs fx
aka back tire, aka hutchinson, undisplaced fx of radial styloid
define chisel fx
proximal radius fx orientated with the long axis of the bone
what is a clay shovelers fx?
aka root pullers fx, avulsion of the spinous process of lower cervical spine
what is a colles fx ?
fall on an outstretched hand . fx of distal radius with posterior angulation of the distal fragment. producing a dinner or silver fork deformity
what is a dancers fx?
avulsion fx of the base of the 5th metatarsal
what is a dashboard fx?
knee hits dashboard in a car accident. fx of the posterior rim of the acetabulum by the femoral head
T/F: Scleroderma is not an autoimmune disease.
False
aka Progressive Systemic Sclerosis
Scleroderma
What organ system is most commonly affected in scleroderma (besides skin)?
GI
CREST stands for...
Calcinosis
Raynaud's
Esophageal dysmotility
Sclerodactyly
Telangectiasia
Scleroderma - sex
Female
Scleroderma - age
30-50
Mauskaupff or "mouselike facies" are associated with this arthropathy.
Scleroderma
T/F: ESR is not elevated in scleroderma.
False
Positive Lab Testing for Scleroderma
ESR, RA factor, ANA
Antinuclear antibodies(ANA) are present in all of the following conditions except:
a) Psoriatic arthritis
b) Scleroderma
c) Systemic Lupus Erythematosus
A
T/F: The most obvious changes seen in scleroderma are seen in the hands.
True
Soft-tissues of the distal digits showing atrophy and retraction associated with what conditions?
Scleroderma and PA
aka distal tuft resorption
Acroosteolysis
Acroosteolysis associated with which condition?
Scleroderma and PA
define duverney fx.
transverse, oblique or vertical fracture of iliac wing. m/c direct lateral blow to ilium
define explosion fx
fracture of distal tibia metaphysial interarticular extension
define fishers fx
(triquetrum), dorsal avulsion of radiotriauetral or lunotriquetral ligament
define flap fx
glenohumoral dislocation with fx of greater tuberosity
define galeazzi fx
fx of distal radius with dislocation of the distal radioulnar joint
define gamekeepers fx
1st MCP (ski pole fx) avulsion fo the ulnar collateral ligament
define golfers fx
lateral rib fx that occurs when a golf club strikes the ground instead of the ball
define hangmans fx
bilateral avulsion of the neural archs from the vertebral body with or without subluxation
define jeffersons fx
burst fx of the atlas
define maissoneuve fx
fx of proximal fibula with rupture of the distal tibiofibular ligaments and interosseous membrane extending proximal to the fibular fracture
define malgaigne fx
fx of pelvic ring composed of individual fx of the superior and inferior pubic rami
define march fx
stress fx distal 1/3 of one of the metatarsals
what is a monteggia fx?
fx involves the proximal ulna with dislocation of the radial head
what is a nightstick fx?
fx occurs to distal third or middle third ulnar shaft
what is a rolandos fx?
a comminuted intra-articular fracture through the base of the first metacarpal bone (the bone located just proximal to the thumb)
what is a second fx?
avulsion fx of the lateral capsular lig secondary to internal tibial rotation while the knee is flexed
what is a smiths fx?
(reversed colles) direst blow to the back of the wrist . fx of distal radius with anterior angulation of distal radius
what is a straddle fx?
double vertical pubis. fx of all 4 pubic rami
what is a teardrop fx?
triangular fragment at the ant portion of the vertebra
what is a toddlers fx?
spiral fx to distal tibia
T/F: Actual cause of psoriatic arthritis is unknown.
True
Psoriatic Arthritis - age
20-50
Pitting, ridging, discoloration, loss of nail or thickening under nail tip(aka subungal hyperkeratosis) is associated with which condition?
Psoriatic arthritis
Psoriatic arthritis - location
Distal joints of the hand
Swelling of the whole digit caused by tenosynovitis seen in psoriatic arthritis is called what?
Cocktail sausage
Arthritis mutilans is associated with which arthritis?
Psoriatic
Psoriatic Arthritis - labs that are positive
ESR and HLA-B27
Radiographic abnormalities in psoriatic arthritis include all of the following except:
a) Uniform loss of joint space
b) Soft-tissue swelling
c) Nodules
d) Tapering bones
e) Periostitis
f) Ankylosis
C
Ivory phalanx is a radiographic feature of which condition?
Psoriatic arthritis
amphetamines
(Dexedrine, Dextrostat)
Schedule II
Acroosteolysis is a part of which 2 arthropathies?
Scleroderma and Psoriatic arthritis
Pencil and cup sign is seen in which arthropathy?
Psoriatic Arthritis
"Balancing pagoda" is seen in which arthropathy?
Psoriatic Arthritis
______ arthritis spares the MCPs while ______ arthritis spares the DIPs.
Psoriatic; Rheumatoid
Psoriatic Arthritis - location
DIPs of hands
what are the two maiin types of proximal femoral fx's?
extracapsular and intracapsular
what are the 3 subtypes of extracapsular proximal femoral fx's?
intertrochanteric- between trochanters
subtrochanteric- distal to intertrochanteric
trochanteric- through trochanter
what are the 3 subtypes of intracapsular proximal femoral fx's?
subcapital- fx of head - neck
transcervical- accross middle of femoral neck
basicervical- accross base of femoral neck
what is the most common carpal bone to fracture?
scaphoid
what is the ssecond most comon carpal bone to fx?
the triquetrum
what is th most common carpal bone to dislocate?
lunate
what is the sign assoc with the dislocation of the lunate?
Pi sign
c sign
spilled tea cup sign
what the types of shoulder dislocations?
glenohumoral dislocation
inferior
superior
a/c separations
posterior
what is the m/c direction for glenohumoral dislocation?
anterior - 95%
aka's - hill-sachs (hatchet)
flap - greater tuberosity
bankart lesion
what sign is associated with a posterior glenohumoral dislocation?
rim sign
T/F: S/I involvement of psoriatic arthritis (PA) is bilateral but asymmetrical.
True
Ankylosis is likely to be seen in which of the following conditions in decreasing order of frequency:
a) AS, RA, PA
b) AS, PA, RA
c) PA, RA, AS
d) RA, AS, PA
B
Erosions and proliferation of the Achilles and plantar ligaments of the calcaneus is seen in which arthritis?
Psoriatic
M/C area of the spine affected in psoriatic arthritis
Thoracolumbar
Non-marginal osteophytes are seen in which of the following arthritises? (MACA)
a) AS
b) RA
c) Reactive arthritis
d) PA
e) Scleroderma
A, B, D
how many types of Ac separation are there?
6.
what is the m/c fx of the elbow for an adult? child?
child - supracondylar fx of humorus
adult- radial head
define lipohemarthrosis
mixture of blood and fat in a joint capsule following trauma. will see fluid-fluid level
what is the m/c location for lipohemarthrosis to occur?
the knee (1st)
also seen in hip and elbow
what is the substance deposited in the joint that produces gout?
monosodium urate
what is a mass of monosodium urate deposited in the joint called?
tophus
aka for gout
podagra- gout in the foot
does gout m/c affect males or females?
males - 20:1
m/c age of onset for gout?
40yrs old
family history of gout affects males or females more?
females
what is gouts ethnic preference?
polynesian
new zealand
filipino
what are 4 classifications of gout?
asymptomatic hyperuricemia
acute gouty arthritis
polyarticular gouty arthritis
chronic tophaceous gout
where and what symtoms are assoc with acute gouty arthritis?
lower extremity, 1st mtp, intertarsal joints, knees - a few joints or less. acute inflammation in the early morning
what areas are affected by polyarticular gouty arthritis?
small joints of the hand, wrist and elbow.
1st mtp, intertarsal joints, knees
where does chronic tophaceaus gout take place?
multiple attacks on the elbow , hand, wrist , knee, foot and synovium. the tophi deposit in avascular areas.
m/c location of arterial injury as related to fracture
Popliteal artery
If blood supply becomes cut off due to injury causing a rise in pressure this clinical syndrome results immediately.
Compartment syndrome
T/F: Compartment syndrome is a medial emergency.
True
This infection often follows 1-3 days after an open fracture or bowel perforation.
Gas Gangrene (Clostridium perfringens)
Aka Sudeck's atrophy
Reflex Sympathetic Dystrophy
what are laboratory findings assoc with gout?
increased ESR
increased leukocytosis
increased uric acid
how do we manage gout in the acute phase?
Colchicine, ACTH, & phenylbutazone
Avoid aspirin, low calorie diets, & diuretics
how do we manage long term gouty arthritis?
Drugs that promote uric acid secretion
Increase fluids, decrease purine intade, avoidance of salicylates
what radiographic changes are assoc with gout?
Soft tissue: increase in density "lumpy bumpy", periarticular
uniform loss of joint space
bone erosions: marginal- pannus "bare area", periarticular- dense sclerotic overhanging margin sign metaphyseal/diaphyseal, intraosseous- tophi collect inside the bone and create punched out lesion appearance in the subchondral bone
normal bone density
secondary degenerative changes
chondrocalcification
AVN
what area is most affected by gout?
lower extremity
Infection that occurs in 15% of open fractures but is rare in closed fractures.
Osteomyelitis
Heterotopic bone formation at the site of injury of a muscle.
Myostitis ossificans
Complication of fracture where bony fusion occurs between two bones that are close to each other.
Synostosis
aka osteonecrosis
Avascular necrosis
M/C location of post-traumatic osteolysis
Distal clavicle
Cause of osteonecrosis
Blood supply has been interrupted
T/F: DJD is a delayed complication of a traumatic injury.
True
Disuse can lead to this delayed complication following traumatic injury.
Osteoporosis
Lack of immobilization, altered circulation and infection can lead to this delayed complication following traumatic injury.
Nonunion
This delayed complication of traumatic injury can result in pseudoarthrosis.
Nonunion
Top 2 m/c sites of nonunion following a traumatic fracture.
Scaphoid and midclavicle
Normal osseous healing with abnormal positioning is called...
Malunion
Lead arthropathy and toxicity is a delayed complication that typically occurs following this specific traumatic injury.
Gunshot
How many types of Salter-Harris fractures are there?
5
aka Salter-Harris fractures
Epiphyseal fractures
what joint is m/c affected by gout?
1st MTP, with met head erosions
overhanging margins. tophi
what radiographic changes are assoc with gout in the hands?
asymmetric distribution
erosions
soft tissue swelling
normal bone density
what radiographic changes are assoc with gout in the knee?
erosions of the me
dial and lateral condyles
prepatellar tophi
what radiographic changes are assoc with gout in the elbow?
erosions of the olecranon
soft tissue swelling
tophi in the olecranon bursa "rising sun appearance"
what is a fracture?
interruption of the bony cortex
Isolated injury through the physis (growth plate) describes this type Salter-Harris fracture.
Type I
Fracture through the physis and a small portion of the metaphysis describes this type of Salter-Harris fracture.
Type II
Fracture through the physis and into the epiphysis describes this type of Salter-Harris fracture
Type III
Fracture extending through the metaphysis, physis and epiphysis describes this type of Salter-Harris fracture
Type IV
Compressive injury to the physis with no associated fracture to the epiphysis or metaphysis describes this type of Salter-Harris fracture
Type V
Slipped Capital Femoral epiphysis is an example of this Salter-Harris fracture type.
Type I
M/C Salter-Harris fracture type
Type II
Small metaphyseal portion of the Type II Salter-Harris fracture is called what?
Thurston-Holland fragment
M/C site of Type III Salter-Harris fracture
Distal tibia
Type of Salter-Harris fracture considered an intra-articular fracture.
Type III
Oblique or spiral fractures in the long bones are typical with this type of Salter-Harris fracture
Type IV
M/C location of Type IV Salter-Harris fracture for a pt <10 yoa
Lateral condyle
M/C location of Type IV Salter-Harris fracture for a pt >10 yoa
Distal tibia
Surgical intervention may be necessary on these two Salter-Harris type fractures.
Type III and IV
Common residual effect of this type of Salter-Harris fracture is limb shortening secondary to premature closure of the physis.
Type V
what is a closed fracture?
A fracture that does not communicate with the outside environment
what is an open fracture?
a fracture that communicates with the outside environment
what is a comminuted fracture?
A fracture with two or more bony fragments
An isolated triangular fragment is called a “butterfly” fragment
what is a non-comminuted fracture?
A complete fracture that has only one fragment
what is the first and best imaging modality to use for fractures?
conventional radiography
when is stress radiography most commonly used?
AC joint, knee and ankle injuries
when is CT used for fractures?
regions of complicated anatomy - spine , facial bones, pelvis, mid/hindfoot
when is MRI used best when dealing with fractures?
single regions that require a high specificity
when is scintography helpful for fractures?
when someone has a stress fracture
when is angiography useful when dealing with fractures?
when vascular abnormalities are suspected.
define avulsion fx
occurs at attachment of a ligaent or tendon. fragment is pulled from the bone
define dislocation
complete loss of articular congruity
define subluxation
partial separation of joint surfaces w/o complete incongruity of the joint components. (not a chiropractic subluxation)
what is diastatic?
separation injury of a synarthrodial joint
ex: symphysis pubis, sutures
define occult.
fracture w/o radiographic evidence
use bone scan or MRI, re-examine 10-14 days to visualize fx
define pathological fx.
bone weakend by disease
typically a transverse fx
define stress fx.
occurs from repeated stress.
m/c MRI used
high t1, high t2 with a linear area of low intensity
what happens with the pt clinically with a stress fx?
pain with activity relieved by rest
tenderness, soft tissue swelling
what are two types of stress fx's?
fatigue and insufficiency
what is the diff between a fatigue fx and an insufficiency fx?
fatigue: abnormal stress on a bone
insufficiency: normal stresses on an abnormal bone
what causes a bone bruise?
trabecular microfractures typically the result of compression or impaction
very high on T2
what are chondral and oteochondral fx's?
fx through the joint cartilage or through the cartilage and subchondral bone
what are some classic examples of chondral and/or osteochondral fx's?
glenoid region following dislocation
patella/lateral femoral condyle following patellar dislocation
osteochondritis dissecans
what are the differences between neurologically unstable and unstable fractures?
unstable- displace when reduced nonsurgically or immobilized
neurologically unstable - in danger of damaging neural structures
oblique fx's are transverse lines in the bone. but at what degree?
45
what forces typically cause a oblique fx?
compression
bending
torsion
what degree to the long bone does a transverse fx run?
90 degrees
what commonly causes a trasverse fx?
bending force
avulsion fx's, and pathological fx's
what type of force causes a spiral fx?
torsion and axial compression
what bones are commonly affected by spiral fx's?
tibia and humerous
what areas are commonly affected by stellate fx's?
flat bones or patella where the line extends radially from the center point
what type of force causes a stellate fx?
direct blow
what is an angular deformity?
directional change of the fracture fragment relative to the long bone
distal vs proximal
how has a fracture fragment moved if it is considered varus? valgus?
varus - toword midline
valgus - away from midline
what is apposition of a fx?
amount of transverse displacement or bony contact of a long bone shaft
how is apposition described?
a percentage of cross-sectional diameter of the dominant(proximal) fragment
define complete apposition.
100% undisplaced
what is seen when the two ends of the broken bone overlap.
overriding or bayonet appearance
(bone shortens)
what is distraction of a fx?
longitudinal separation of the fracture fragment.
define rotation of a fx.
twisting of one fracture fragment relative to another around the long axis of the bone. (torsion)
ref both prox and distal joints
what are two types of fracture reduction?
closed - manipulation and casting of the extremity
open- surgery and harware used to align the broken bones
what are two types of fracture fixation?
internal- placement of cortical plate with pins or screws
external- pins through the skin into the bone. this is used for an infected area or near the end of the bone
how long does a fx take to heal in kids/adults?
kids- 4-6 wks
adults- 6-12 weeks
what factors determine how fast a fx heals?
age
location
bone/soft tissue devitalization
fragment apposition
immobilization
what are the 3 stages of healing?
circulatory(inflammation)
reparative (metabolic)
remolding (mechanical)
what are the 3 sub-phases of circulatory phase?
cellular-
vascular
primary callus
what happens during the cellular subphase?
hematoma forms
inflammatory reaxn
granulation tissue brings undifferentiated mesenchymal cells
what hppens during the vascular subphase?
new blood vessels form
decreased hyperemia
what happens during the primary callus subphase?
rapid deposition of ostoid
describe the reparative (metabolic) phase of fx healing.
40% of healing,
callus secrretion
woven bone replaced by mature bone
describe remolding (mechanical phase of fx healing
50-70% of healing
bone remodeling and callus along stress lines
restoraiton of marrow cavity
What are the akas for AS?
Marie-Strumpell’s disease, von Beckterew, rheumatoid spondylitis
AS is an inflammatory __________ ____________
Seronegative spondyloarthropathy
Most commonly affects young adult _______
males
Distribution is mostly limited to the _____ skeleton and large _______ joints
axial, proximal
Choose that apply to AS
Tachycardia conduction defects
Bradycardia conduction defects
Pulmonary insufficiency
Aortic insufficiency
Myocardial fibrosis
Aortitis/Aneurysms
Tachycardia conduction
Aortic insufficiency
Myocardial fibrosis
Aortitis/Aneurysms
Pulmonary - Fibrosis of the upper/lower lung fields?
upper
Inflammatory reaction is similar to RA but much more intense (T/F)
F- less intense
Pannus formation occurs in the affected synovial joints (T/F)
T
It also attacks the cartilaginous joints of the spine and enthuses “whiskering” (T/F)
T
Referring to the question above- it is inflammation at the costovertebral junction followed by a healing response of the bone (T/F)
F- discovertebral junction
Eventual conversion to bone of the outer layers of annular fibers occurs and is called a ____________
syndesmophyte
Put the formation of syndesmophytes in the correct order
A- Appears a “shiny” corner sign followed by ossification of the outer layers of the annulus
B- Romanus lesion occurs
C- Creates a squared contour on the vertebral body
B C  A
What is the laboratory test for AS that is positive (>90%)
HLA B27
ESR (increased/decreased), Rhematoid factor (positive/negative),
ANA (positive/negative)
increased , neg , neg
What is the hallmark of AS?
bilateral sacroillitis
Bilateral (symmetrical/ asymmetrical) changes are typical
symmetrical
What are the three stages of AS?
1- Pseudowidening, loss of distinct articular margins
2- Erosive and sclerotic changes, “Rosary bead” appearance
3- Ankylosis- Narrowing and obliteration of the joint spoace, “Ghost” joints, “Star” sign
Spondylitis in the thoracic/ Lumbar occurs in about 65% of patients (T/F)
F-50%
Referring to the question above, as a rule it develops after SI disease (T/F)
T
Thoracolumbar is the most common site of involvement in AS, and it typically progresses symmetrically without skip lesions (T/F)
T
In Cervical, May see erosions of the ______ and an increased ADI (> ____mm in adults)
dens, 3mm
What sign is present in the Cervical with AS?
shiny odontoid sign. increased density of the odontoid
What cervical segments have syndesmophyte formation?
C2/3
C6/7
What is the most common peripheral joint involved?
Hip Joint
In the Hip Joint: ______ migration with (uniform/non-uniform) loss of joint space
axial , uniform
AS in the Hip can lead to protrusi acetabuli, and progress to bony ankylosis (T/F)
T
Hip is the most common peripheral joint, what is the second most common?
shoulder
Erosion of the entire lateral aspect of the humeral head is “______ sign”
Hatchet
Ankylosed segments are subject to fracture termed “_______-______” fracture
carrot stick
What are the DDX for Anderson lesions (pseudoarthrosis- a level becomes mobile resulting in instability and adjacent destruction)?
infection, neuropathy
Name two neurospinal complications associated with AS?
spinal stenosis
cauda equina syndrome-arachnoid diverticula
What are the most common locations for spinal trauma?
c1-2, C5-7, T12-L2
What are the percentages of fractures in the cervical/thoracic/thoracolumbar regions that are associated with neurological damage?
cervical - 40%
thoracic spine- 10%
thracolumbar junction- 4%
______% of spinal fractures are associated with other fractures, ____% of spinal injuries have no associated fracture
20%, 10%
What is the most common line of force?
flexion
What imaging modality has been shown to demonstrate nearly 100% of cervical spine fractures?
CT
What is the modality of choice to demonstrate soft tissue, neurological and vascular damage?
MRI
What are the three column models proposed by Denis (what does each model include) and what are they designed for?
Originally designed for thoracolumbar injuries but can be extrapolated for the cervical spine
-Anterior: includes 2/3rd of the vertebral body, IVD and ALL
- Middle: includes the posterior 1/3rd of the vertebral body, IVD and PLL
-Posterior: includes the posterior osseous arch and posterior ligaments
-Capsular ligaments
-Ligamenta flava
-Interspinous
-Supraspinous
What column is the most important in determining the potential for instability?
middle column
Grounds for removal of Trustee include:
(i) a serious breech of trust (ii) lack of cooperation among co-trustees (iii) unfitness, unwillingness, or persistent failure to administer or (iv) a substantial change in circumstances.

Key:
List three types of spinal instability?
First degree (mechanical)
Second degree (neurologic)
Third degree (mechanical and neurologic)
What type of spinal instability is it for these cases:

1-The spine is insufficiently constrained against buckling and angulation (this type places the patient at risk for progressive chronic kyphosis)
2- Includes cases in which progressive osseous displacement and progressive neurologic injury may develop
3- Applies to patients at risk for delayed neurologic compromise even if no deficit exists at presentation
1-First degree
2-Third degree
3-Second degree
What is Vertebral body squaring?
Loss of normal anterior vertebral body concavity
what is a Shiny corner sign?
-Transient reactive sclerosis adjacent to Ramanus lesion. A precursor to syndesmophyte formation
what is a trolley track sign?
Ossification of the apophyseal joints, interspinous and supraspinous ligaments
what is bamboo spine? aka poker spine?
Secondary to uniform and symmetric bridging of syndesmophytes, undulating and segmented appearance of the spine, aka
what is a Ghost joint?
Visualization of articular cortex through an ankylosed joint
what is a star sign?
Ossification of superior sacroiliac ligaments, creates a triangular opacity
what are syndesmophytes?
Inflammatory ossification of a spinal ligament, marginal or non marginal, marginal are suggestive of AS/Enteropathic
what creates a dagger sign?
Ossification of the supraspinous and interspinous ligaments
what creates a romanus lesion?
An erosion of anterior vertebral body margin at the annulus insertion. A precursor to syndesmophyte formation
what creates a railroad track sign?
Ossification of the apophyseal joints only
what creates a rosary bead appearance?
Undulating appearance of sacroiliac articular margins
gazpacho means ...
Andalusian soup made from tomatoes, cucumbers, pepers and bread, served chilled
sobaco means...
armpit
huerta means...
truck farm
Dorsal subluxation of MTPs w/ fibular deviation seen in RA.
Lanois deformity
M/C location of RA below C1/C2
C2-C4
SLE - gender
Female
SLE has ANA antibodies?
yes
T/F: RA has reducible/reversible deformities while SLE does not.
False. (Switch it).
aka osteonecrosis
AVN
Orthopedic tests used for AS:
1) Amoss's sign
2) Chest expansion
3) Forestier's bowstring
Marginal syndesmophytes are suggestive of RA/Reiter's or AS/Enteropathic?
AS/Enteropathic
Microbes associated with enteropathic arthropathy
1) salmonella
2) Shigella
3) Yersina
Most significant physical correlation of PA
Nail involvement
Lesions on soles of feet and palms of hands as seen in Reiter's
Keratoderma blennorrhagica
Reiter's triad
1) Conjunctivitis
2) Urethritis
3) Arthritis
Periostitis of calcaneus as seen in Reiter's
Lover's heel