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38 Cards in this Set

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Gives rise to the ventricular system of the brain
Neural Tube Lumen
Chorionic villus sampling (CVS)
8-10 weeks
Gives rise to dorsal root ganglia of the spinal cord
Neural Crest
Amniocentesis
Couple whose first child had trsomy 18; wants safest procedure
Which procedure is most accurate in detecting fetal anomalies?
Level II ultrasound
Uninterpretable result
20 ng/mL
Which of the brain regions is both a primary and secondary brain vesicle?
Mesencephalon
Which of the brain regions becomes the medulla?
Myelencephalon
No prenatal diagnosis available
Couple whose first child had cerbral palsy
Possible spina bifida; normal karyotype in one twin
Amniotic alpha-fetoprotein (AFP) 6 multiples of mean (MOM); karyotype 46, XY
Amniocentesis
12-16 weeks
Chorionic villus sampling (CVS)
Couple whose first child had Tay-Sachs disease and whose church and relatives strongly disapprove of prenatal diagnosis
Which of the brain regions is the upper division made by the pontine flexure?
Metencephalon
Down syndrome
Fetal karyotyping to determine sex
A newborn develops jaundice that increases over the first week. Most of the bilirubin is indirect, and the red blood count is normal without signs of antibody reaction. The fater is blood type O positive and the mother blood type O negative. Mother recalls receiving a shot early in pregnancy "because of bad blood." The child has a tense abdomen with an enlarged liver, blood in the stool, and abdominal x-ray shows dilated loops of small intestine. The most likely diagnosis is:
Intestinal malrotation
The internal capsule develops from a swelling on the floor of the cerebral hemispheres called the:
Corpus striatum
A large birth weight infant born to a mother with insulin-dependent diabetes mellitus. There is a heart defect, small jaw and malformed ear on the left. The most urgent laboratory investigation would be:
Blood sugar
Neuroblasts in the spinal cord form the:
Ventral nerve roots
Nonspecific X-linked recessive mental retardation
Fetal karyotyping to determine sex
Possible fetal Down syndrome
0.5 multiples of mean (MOM) for gestational age by ultrasound 15 1/2 weeks
A female neonate develops respiratory distress soon after birth. She has a full head of hair, well-developed ears, excellent muscle tone and reflexes. There is a lound systolic heart murmur heard all over the precordium.
Patent ductus arteriosus
Maternal serum alpha-fetoprotein (MSAFP)
Couple of British ancestry
Maternal serum alpha-fetoprotein (MSAFP)
12-16 weeks
A newborn has decrease muscle tone with a frog-leg posture, ears incompletely separated from the scalp, and undescended testes. He is normal after birth, but develops respiratory distress after four hours. Chest x-ray shows a homogenous, hazy infiltrate throughout the lung fields.
Decreased lung surfactant
Possible fetal neural tube defect
5.5 multiples of the mean (MOM) for getational age by ultrasound of 15 1/2 weeks
A newborn fails to breath at delivery and must be resuscitated. She is born after a long and difficult labor, with concerns about decreased oxygenation as manifest by slowing of her heart beat on the fetal monitor. The amniotic fluid is dark green at delivery. She develops severe respiratory distress, and a chest x-ray shows a fluffy infiltrate in her right lower lobe.
Meconium aspiration
A newborn develops jaundice that reaches a peak value at 3 days. All of the bilirubin is indirect, and the red blood count is normal without signs of antibody reaction. The father and mother both have blood type O negative. The most likely diagnosis is:
Physiologic jaundice of the newborn
Normal karyotype; amniotic alpha-fetoprotein (AFP) level uninterpretable unless correlated with population mean and gestational age.
Amniotic alpha-fetoprotein (AFP) concentration of 30 ng/mL; karyotype 46, XY
A 2-month old child presents with irritability, frequent crying, and poor sleep. The initial diagnosis was colic, but you note an enlarged globe that is tense and painful on the right. The correct diagnosis is:
YO MAMA! J/K
Congenital glaucoma with buphthalmos on the right
Cordocentesis
Fetal anomalies detected by ultrasound at 26 weeks' gestation
A newborn develops jaundice that reaches a peak value at 3 days. All of the bilirubin is indirect, and the red blood count is slightly decreased with antibody detected on their surface. The father is blood type A negative and the mother blood type O negative. The most likely diagnosis is:
ABO blood group incompatibility
What is recommended for every couple interested in prenatal diagnosis?
Genetic counseling
Tay-Sach's disease
Hexosaminidase assay of chorionic villi
Which structure and germ layer is responsible for producing witch's milk in newborns?
Lactiferous ducts from ectoderm
Normal twin gestation
Amniotic alpha-fetoprotein (AFP) 2 multiples of mean (MOM) for gestational age of 15 weeks estimated from ultrasound; karyotype 46, XY
The enamel organ surrounds an internal dental papilla at week 8.
Cap stage
Odontoblasts appear in the dental papilla at week 10.
Bell stage
Cystic fibrosis
Fetal DNA testing if parents carry the F508 or other known mutations