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17 Cards in this Set

  • Front
  • Back
conivaptan
Vaprisol
LD 20mg IV over 30 min, 20mg CIV
DNE 4 days
tolvaptan
samsca
15mg po qd (max 60)
who needs stress ulcer prophylaxis
mechanical ventilation
coagulopathy
sepsis
traumatic brain injury
burn patients
acute renal failure
high dose corticosteroids
what causes stress ulcers
reduced blood flow to gut, this results in the breakdown of gastric mucosal defense mechanisms
stress ulcer prophylaxis
H2RA and PPI
CONs
H2RA (trhombocytopenia, mental status cx, tachyphylaxis)
PPI (increased cdiff risk, pneumonia)
Risk for DVT
Previous VTE
Surgery/Trauma
Immobility
Cancer
Pregnancy/ estrogen therapy
Age
Acute illness/infection
Heart Failure/ acute MI
Thrombophilia
Venous obstruction/ indwelling catheter
DVT px
-UFH
- LMWH
-Xa agents
UFH- 5000 units SC BID to TID
lovenox- 30 mg SC BId or 40 mg SC bid (reduce to 30 mg daily if CrCL,30)
fondaparinux 2.5mg po daily (not in pts <50 kg or with CrCl<30)
rivaroxaban - 10 mg daily (not in pts w/ CrCl <30)
2 topical anesthetics
lidocaine (xylocaine) and benzocaine
4 inhaled anesthetics
desflurane(suprane)
sevoflurane (Ultane)
isoflurane (Forane)
Nitrous oxide
3 injectable anesthetics
bupivacaine (marcaine, sensorcaine)
lidocaine (xylocaine)
ropivacaine (naropin)
warning for bupivacaine
FATAL if given by IV route
how do anesthetics work
Block the initiation and conduction of nerve impulses by decreasing the neuronal permeability to sodium ions
Side effects of anesthetics
hypotension, bradycardia, NV, drop in body temperature and shivering

Inhaled anesthetics can cause malignant hyperthermia that needs to be treated with dantrolene
NMBAS warning
no analgesia or sedation provided
ISMP high risk drugs must be labeled "Warning, paralyzing agent"
Depolarizing neuromuscular blocking agent
succinylcholine binds to and activates acetylcholine receptor and desensitized it

used for intubation
NOT used for continuous blockade
***possible malignant hyperthermia
Non depolarizing NMBA
atracurium -- short
cisatracurium (Nimbex)- short
pancuronium- long and may accumulate with renal or hepatic dysfunction
rocuronium (zemuron)- intermediate
vecuronium- intermediate can accumulate in organ dysfunction
Non depolarizing NMBA and SE
flushing, bradycardia, hypotension, quadriplegic myopathy syndrome with long term use