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37 Cards in this Set

  • Front
  • Back
What does the plasma membrane do? (2 things)
-Lets things into or out of the cell.
-Transmits signals across/along surface
What happens in the nucleus?
Protects, replicates, synthesizes and expresses genetic material (DNA).
What cell organelles have two unit membranes?
Nucleus, mitochondria
Heterochromatin vs euchromatin: density of staining? Actively being transcribed?
Heterochromatin- densely staining, less active
Euchromatin- less intense staining, actively being transcribed
What protein are microtubules made of?
tubulin
What supports the force generating components of cilia and flagella?
Microtubules
What component of the cytoskeleton forms the mitotic apparatus?
Microtubules
What are basal bodies?
The location where cilia are anchored
What protein makes up microfilaments?
actin
What do ribosomes do? Visible under light microscope?
Make proteins. No, too small but can see darkly stained regions where ribosomes are concentrated.
What is the endoplasmic reticulum? What does it do?
Branching, interconnected tubules. Enclose a space inside (ER lumen).
What does smooth ER do?
(Lots!)
-Synthesizes steroid hormones
-Detoxifies lipid-soluble drugs
-uses P450 enzmes to convert water insoluble drugs into compounds more water soluble
-synthesizes lipids for lipoproteins and phospholipids
-involved in glucose metabolism and storage
-stores Ca2+ and keep it separate from the rest of the cell.
-(Sarcoplasm) Can release Ca2+ from skeletal and cardiac muscle cells
What does the Golgo apparatus do?
-carbohydrate synthesis
-post translational modification of proteins (glycosylation, phosphorylation, sulfation)
-
What are the regions of the Golgi apparatus?
cis-Golgi network - medial Golgi cisternae - trans-Golgi cisterna - trans-Golgi network
What happens to the products coming out of the Golgi apparatus?
-some go to cell surface
-some go to lysosomes
-some go to cytoplasm to be stored in vesicles (secretory proteins, neurotransmitters)
What cell type does not have mitochondria?
RBC's
What do mitochondria do?
-transform chemical energy into ATP
What cell organelle is "flexible, mobile, and self-replicating?"
Mitochondria
What do lysosomes do?
Major digestive organelles of the cell.
Do lysosomes have a single or a double unit membrane?
Single unit membrane
What kind of environment exists inside a lysosomes?
Acidic, pH around 5. Maintained using Na+/K+ pump.
Do peroxisomes have a single or double unit membrane?
Single unit membrane.
What do peroxisomes do?
(Lots!)
-detoxify substances
-degrade certain lipids
-oxidize organic substates, producing hydrogen peroxide in the process (toxic)
-convert hydrogen peroxide (formed above as well as through other cellular activities) into water and oxygen
Where are peroxisomal enzymes synthesized?
On cytoplasmic ribosomes (hanging out in the cytoplasm)
What organelles are surrounded by a single unit membrane?
Lysosomes and peroxisomes
What is the "brush border?"
Microvilli- they're too small to resolve under a light microscope so the edges just appear fuzzy.
Where are microvilli found?
Small intestine and kidney
The proteins that are permanent components of the cytoplasmic ribosomes in eucaryotic cells are made where?
By ribosomes in the cytoplasm that are not bound to rER
What can you tell about a region on the plasma membrane that has most of the proteins?
That area is the enzymatically active area on the plasma membrane.
What cytoskeleton component forms the mitotic spindle?
Microtubules
What cytoskeleton component forms the flagella?
Microtubules
These proteins make up which component of the cytoskeleton:
keratins, vimentin, desmin?
The intermediate filaments
Which stain (H&E) is responsible for the blue color?
Hemetoxalin
Which stain (H&E) is responsible for the pink color?
Eosin
What organellle does Dr. Borst mean by "lavender cytoplasm?"
rER
Why isn't the Golgi apparatus stained by H&E dye?
H&E doesn't stain membranes.
What does it mean when a cell has elongated mitochondria and an infolding of the plasma membrane?
The cell probably is responsible for pumping ions into and out of the cell.