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15 Cards in this Set
- Front
- Back
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What is the first line drug for the treatment of chronic stable angina
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beta blocker
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What drug is most useful in aborting an attack of stable angina
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sublingual nitrate
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What classes of drugs can prophylactically treat stable angina
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beta blockers
nitrates calcium channel blockers ranolazine |
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What classes of drugs can prophylactically treat Prinzmetal's angina
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nitrates
calcium channel blockers |
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MOA - beta blockers in treating chronic stable angina
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block beta1 on the heart
reduce heart rate, contractility and oxygen demand |
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MOA - nitrates in treating stable angina
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dilates veins
reduces preload, wall stress and oxygen demand |
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MOA - nitrates in treating Prinzmetal's angina
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dilates coronary arteries, relieves vasospasm
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MOA - DHP calcium channel blockers in treating stable angina
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dilates arteries - decreases PVR, afterload, wall stress and oxygen demand
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What effect does isosorbide dinitrate have on preload, afterload and contractility
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reduces preload, little effect on afterload (reduction), no effect on contractility
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A patient began a drug for their stable angina. They started complaining of palpitations. what did they most likely take?
nitrate, beta blocker, non-DHP CCB |
nitrate
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A person is put on the nitroglycerin patch. They are told to take the patch off before they go to bed. Why?
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Chronic use can cause tolerance. Need a nitrate free interval every day.
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Why are nitrates not used for the treatment of chronic hypertension?
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you have high BP 24 hours a day, and you need a nitrate free interval to prevent tolerance to the drug
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A person had taken sildenafil. If they take a nitrate, what can happen?
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Don't break down the NO that is generated and severe hypotension
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Which of the following will decrease heart rate and oxygen demand in treating stable angina?
nitroglycerin, hydrochlorothiazide, diltiazem, nifedipine |
diltiazem
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A patient is on a beta blocker for stable angina. They are still having problems. Which of the following would be best to combine with the beta blocker?
amlodipine, verapamil |
amlodipine
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