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108 Cards in this Set

  • Front
  • Back
Narrowing of a coronary artery, which prevent adequate blood supply to the myocardium.
Ischemia.
Coronary artery narrowing to the point that heart muscle is damaged.
Infarction.
Etiology of ischemic heart disease. (4)
Atherosclerosis
Coronary artery spasm
Embolus
Dissection
What is the most common indication for echo?
Ischemic heart disease.
What does echo look at in evaluating ischemic heart disease?
Systolic wall thickening
Endocardial motion
Global and regional function
Which coronary arteries can be seen with TTE and TEE?
Proximal Left and Right main coronaries.
What is the gold standard in for coronary anatomy?
Cath.
How can you see infarcted myocardium?
There will be wall abnormalities at rest.
Wall thickness of acute MI?
Normal
Acute MI on echo?
Normal wall thickness.
Systolic thickening and endocardial motion reduced or absent.
At what point of coronary artery stenosis is ischemia present?
70%
What is ischemia?
A reversable imbalance in oxygen supply vs. demand ratio. Due to narrowing in the coronary arteries.
In ischemia, what's going on with wall motion at rest?
Normal. Unless there was a previous MI.
Sequence of events with Ischemia.
1. Perfusion defect.
2. Diastolic function abnormality.
3. Segmental wall motion abnormality.
4. Ischemic ST changes on ECG
5. Clinical angina.
What is the most challenging task in echo?
Regional wall motion analysis.
What needs to be adjusted to view all the wall segments?
Gain
Harmonics
Contrast
Wall Motion Score Index.
1 -- Normal
2 -- Hypokinetic
3 -- Akinetic
4 -- Dyskinetic
5 -- Aneurysmal
What is an abnormal score on the WMSI?
Anything above 2.
Formula for WMSI?
Sum of segments scored/# visualized.
Which views do you use for the WMSI?
Long, Short, 4, and 2.
Irreversible injury to the myocardium due to ischemia?
Myocardial Infarction.
Order of events in Myocardial Infarction.
1. Hypokinnesis, akinesis, dyskinesis of the affected wall segment
2. Thinning and increased echogenicity. Hyperkinesis of the opposing wall segments.
What kind of infarct will result in the most thinning of a wall segment?
Transmural infarct, meaning all layers.
How can a WMA be fixed and what's the window of time?
WMA may persist for 72 hours, and is reversed when perfusion resupplies it.
What exhibits prolonged dysfunction after perfusion?
Stunned myocardium.
What is the story with hibernating myocardium?
It is receiving enough blood to stay alive, but not enough to move. Motion can come back.
What exhibits prolonged dysfunction after perfusion?
Stunned myocardium.
Prolonged ischemia may result in what that can be regained?
Hibernating myocardium.
A myocardial infarction is usually due to what?
An acute thrombotic occlusion from a ruptured plaque.
2 to 7 days post MI, mechanical complications may occur due to softening of the myocardial tissue. What are these complications?
Free wall rupture.
VSD
Papillary muscle rupture
Aneurysm
MR
LVE
LV thrombus
Which papillary muscle is more likely to rupture?
Posteromedial, because it is supplied by a single coronary artery.
How much more likely is a posteromedial pap muscle rupture likely than a anterolateral pap muscle rupture?
6 to 10, because it has single artery supply, while the anterolateral has 2.
What are the complications of MI, not due to myocardial softening?
Arrhythmias
Heart block
LV systolic dysfunction
Cardiogenic shock.
What is the treatment for a ruptured papillary muscle?
Valve replacement.
How does a ruptured papillary muscle look on echo?
Flail leaflet with attached mass, prolapses into the LA.
Why does a free wall rupture occur?
Due to necrosis, within one week of MI.
What is the prognosis of a ruptured free wall?
Usually fatal due to tamponade or electrical mechanical disassociation.
Symptoms of free wall rupture?
Acute hypotension
Severe heart failure
Loud, harsh systolic murmur.
What should you look for to see a free wall rupture?
A thin wall, a jet, effusion.
What is the only way to treat a ruptured free wall?
Surgical repair.
What can happen in a ruptured free wall, making the patient very lucky?
Psuedoaneurysm.
How long after an MI is a pericardial effusion likely?
2-4 days.
What happens due to an immune response 1-12 weeks post MI?
Dressler's syndrome.
How many infarct patients have a septal rupture?
1 to 3%
Post MI, when does a septal rupture occur?
Usually within the first week.
Who is likely to have a septal rupture?
Elderly women without previous MI
What is an indicator of a septal rupture?
A new systolic murmur.
What type of shunt can be expected with a septal rupture?
L to R, In a thinned, dyskinetic area.
What is a psuedoaneurysm?
Essentially a hematoma.
Narrow neck.
Partial filling with thrombus.
Wall is pericardium
What motion is seen in a true aneurysm?
Dyskinetic.
Where is an aneurysm likely?
Apex.
What likely is seen with an aneurysm?
Thrombus.
What would a thrombus from MI look like?
Laminated or mural, concave contour
Treatment for MI?
Thrombolysis, 4 hours.
Anticoagulation
Percutaneous transluminal coronary angioplasty
Coronary Artery Bypass Graft
Intra-Aortic Balloon Pump
What does IABP stand for?
Intra-aortic balloon pump.
How does IABP work?
Increases perfusion by inflating during diastole, increasing perfusion pressures in the coronary arteries. Deflates prior to systole, thus decreasing afterload.
How big is the balloon used in IABP?
40cc
In MI, why is MR seen?
Not due to LVE, but rather aortic root dilation or valve disease.
What Echo looks for.
Segmental pattern of LV function
EF for overall function
LV thickness
LVID
MR
PAP
AR
reduced function - look for thrombus.
When not to use modified Simpsons?
When difference of lengths is greater than 20%
Methods of measuring global LV systolic function?
LV end diastolic and end systolic dimensions and volumes
FS
EF
SV
CO
CI
What is an important predictor of mortality after MI?
Global LV systolic function
What gives a percentage change in the LV cavity with systole?
Fractional Shortening.
Fractional Shortening formula?
LVEDD-LVESD/LVEDD x100
Normal fractional shortening?
25-45%
What gives a percentage of LV diastolic volume that is ejected with systole?
Ejection Fraction
Ejection Fraction formula.
LVEDV-LVESV/LVEDV x100
or
LVEDD2-LVESD2/LVEDD2 x100
Normal ejection fraction?
55%-75%
What is the procedure to coordinate pumping action of the ventricles?
CRT - Cardiac Resynchronization Therapy.
What echo test can help identify candidates of CRT?
Tissue doppler.
Outcomes with CRT?
Reduce symptoms
Increase SV
How does CRT increase SV?
Increasing the mechanical sequence of contraction.
In stress echo, images are acquired in a cine loop during what EKG phase?
R wave to just past T wave
Why is stress echo helpful in diagnosing coronary artery disease?
Patient could have normal function at rest.
Increase workload increases myocardial oxygen demand
Ischemia impairs function
What does TMET stand for?
Treadmill exercise test, the EKG test. Echo stress test is better in all ways.
What are the indications for a stress echo?
Diagnosed CAD
RX adjustment for those with CAD
Guide post MI rehab
Pre-op risk stratification
Screen high risk professionals
Assess MV in patients who are symptomatic
Chest pain of unknown origin
Shortness of breath
What are contraindications for stress echo?
Unstable angina
Acute MI 2 days prior
Severe AS
Severe pulmonary hypertension
Significant arrhythmia
Uncontrolled hypertension
Aneurysm
Mobile thrombus
IHSS - due to arrhythmias
Syncope or seizures
How can abnormal wall motion be independent of inducible ischemia?
Conduction abnormalities, like LBBB
Ventricular pacemakers
Right sided pressure/volume overload
What are potential pitfalls of stress echo?
AWM independent of ischemia
Operator dependent
Technical difficult images - obesity, pectus, COPD
Getting patient to goal
How do you achieve an increased cardiac workload?
Exercise
Dobutamine
What are the key elements in stress echo interpretation?
Duration of exercise
Maximum workload
Symptoms
BP response
Arrhythmias
ST segment changes on ekg (ELEVATION OR DEPRESSION)
What is important in image acquisition in stress echo?
Ensure segments are visualized in at least one view
Use comparable views at rest and stress
Record in cine loop
Optimize endocardium
Do it fast - at max workload.
How do you optimize the myocardium?
Harmonics, contrast, TGC
How many peak images need to be obtained?
5 or more
When the images are side by side on quad screen, what do you look for?
systolic thickening and wall motion
What is a normal stress response?
Hyperdynamic walls
Systolic thickening
Decreased systolic cavity
Normal diastolic dimensions
How should a patient be prepped?
NPO for 3 hours
Explain procedure
Rate and rise of treadmill
Patient will be pushed to a goal HR
Patient needs to convey symptoms
Why is dobutamine used in stress echo?
Increases HR and contractility
What is the half-life of dobutamine?
2 min.
How is dobutamine administered?
5mcg/kg/min increased incrementally every 3 to 5 min up to 40mcg/kg/min
What may be added on top of dobutamine to increase heart rate above the 85% goal?
Atropine
What is the normal dobutamine response?
Wall thickening and increased endocardial motion.
What are positive indicators for ischemia with dobutamine?
Areas of hypokinesis or akinesis in a region that had normal function.
If the coronary artery is stenosed proximally, WMA will be present where?
base of the heart.
If the coronary artery is stenosed distally, WMA will be present where?
Toward the apex.
Dobutamine and hibernating/stunned myocardium?
Improvement has been shown with low dose dobutamine (10mcg/kg/min) but then worsening at higher doses.
When to terminate a stress test?
Angina
Wall change (new, worsening of existing)
Significant arrhythmias
Hypotensive response
Hypertensive response
Max dose
Max HR
Intolerable symptoms
At rest, normal wall motion. What should happen in SE for a normal interpretation?
Increased EF, decreased vol, hyperdynamic.
At rest, normal wall motion. What should happen for an ischemia interpretation?
New RWMA, lack of hyperdynamic response.
At rest, RWMA. What should happen for an ischemia interpretation?
Worsening RWMA
At rest, RWMA. What should happen for an infarct interpretation?
Unchanged
What are the advantages of dobutamine SE?
Alternative if they cant exercise
Contrast evaluation
The test ends immediately when you see RWMA
Test for viable myocardium
What are disadvantages to dobutamine?
Functional capacity not assessed.
Operator dependent
Subjective interpretation
Advantages of stress echo?
Low cost (1/2 to 3/4 of nuclear studies)
No irradiation
Portable
Brief
Immediate answers
Ability to see wall thickening
Disadvantages of stress echo?
Operator dependent
Subjective interpretation.
In SE, when do you use contrast?
If less than 80% of the segments can be seen.
How is contrast administered?
Injected into a vein in the arm. Runs through pulmonary system into LV.
What views do you use in SE?
PLAX, PSAX, 4, 2.