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52 Cards in this Set

  • Front
  • Back
Which class of cephalosporin predominately covers gram positive organisms?
first generation
This glycopeptide is active against methicillin resistant gram positive organisms?
Which agent is considered to have the best activity against community acquired methicillin resistant S. aureus?.
TMP/SMZ or Clindamycin
Enterococcus faecalis is a gram positive cocci that is not inhibited by which class of beta lactams
cephalosporins or carbepenems
This antibiotic is a ketolide and has improved activity against penicillin resistant S. pneumoniae
Telithromycin (Ketek)
This is the antibacterial of choice for E. coli in the urine.
This antibacterial is given by IV usually in combination with a beta lactam for gram negative sepsis.
gentamicin, tobramycin or amikacin
This antibacterial use to be one of the most active agents against Pseudomonas aeruginosa that can be given orally and IV but has been experiencing increasing resistance over the past few years.
This beta lactam has the same spectrum as aminoglycocides and is usually used to treat gram negative sepsis in patients who have had a penicillin type I allergy.
This carbapenem is active against extended spectrum beta lactamase producing gram negative organisms, is not active against P. aeuginosa and is dosed once daily.
This is the antiviral agent of choice for the treatment of Herpes simplex.
This antiviral agent is the drug of choice for CMV retinitis.
ganciclovir or valgancliclovir
This is an oral antiviral agent used to treat hepatitis B that does not seem to develop resistance during therapy.
This is the treatment of choice for the treatment of chronic hepatitis C?
pegylated interferon plus ribavirin
The alternative PI based regimen for treating patients with HIV infection that does not appear to cause hyper lipidemia or insulin resistance.
atazanavir plus Epizicom or ATV/r plus Truvada
This is the azole antifungal that is used to treat most Candida albicans infections that are not disseminated
This antifungal agent has been around for 50 years and is still active against most fungi that cause systemic fungal infections.
amphotericin B
Cryptococcal meningitis requires IV antifungal therapy during the first two weeks that consists of this combination therapy.
amphotericin B and flucytosine
This antifungal agent is the first one of a new class of antifungals to be approved for the treatment of invasive aspergillosis
The relatively new antifungal agent that is approved for pulmonary aspergillosis and can be given IV and PO
This antibacterial is one of the components of the induction therapy for tuberculosis and can cause red-green color blindness
This class of synthetic antibacterials has activity against atypical bacteria (C. pneumoniae, mycoplasma, and legionella) as well as Streptococcus pneumoniae.
respiratory quinolones
This anti-infective is often used to treat antibiotic associated diarrhea and also has good activity against anaerobes.
This beta lactam antibiotic is often used as first line therapy for intra-abdominal infections along with an aminoglycoside
piperacillin/tazobactam (Zosyn)?
This antibiotic is recommended as an alternative in combination with primaquin for the treatment of toxoplasmosis.
A new antibiotic in the class of antibiotics known as the glycylcyclines was approved in late 2004 for the treatment of skin and skin structure infections caused by MRSA as well as gram negative organisms.
This cephalosporin is most often used for treatment of outpatient staph and strep infections
cephalexin or cephradine
This cephalosporin is the antibiotic of choice for prophylaxis for most clean surgeries
The cephalosporin that is most commonly used to treat nosocomial infections when Pseudomonas aeurginosa is suspected
This cephalosporin should not be used in neonates because it causes biliary sludging.
This cephalosporin is the one recommended to treat neonatal meningitis and is also one of the two recommended to treat community acquired pneunomia in patients requiring hospitalization.
This beta lactam is the antibiotic of choice for treating penicillinase secreting S. aureus in a hospitalized patient where partenteral therapy is indicated
methicillin or nafcillin
This beta lactam is the anti-infective of choice for the treatment of primary and secondary syphilis
benzathine penicillin
This beta lactam is still considered the antibacterial of choice for the treatment of most upper respiratory track infections.
This beta lactam is a carbapenem that is recommended for empiric broad spectrum coverage for intra-abdominal infections.
imipenem or meropenem
This beta lactam/beta lactamase combination is great for gram negative, gram positive and anaerobic infections with the exception of psedomonas and enterobacter.
This first generation fluoroquinolone is often used to treat uncomplicated and complicated urinary tract infections.
ciprofloxacin or ofloxacin
This is what happens when a fluoroquinolone and an beta lactam are administered concurrently.
This fluoroquinolone is reported to have the highest incidence of hyper/hypoglycemic effects.
Fluoroquinolones and aminoglycosides exhibit bacterial inhibition for one or more hours after their levels drop below the MIC of the organism being treated which is explained by this pharmacodynamic property.
post antibiotic effect
In more severe cases of mycobacterium avium complex (MAC) disease the addition of this agent may be needed during the first few weeks of therapy.
This inexpensive agent is listed as first line therapy for the treatment of community acquired pneumonia in patients treated in the outpatient setting without prior antibacterial therapy within the past three months.
This agent is the preferred agent for use as primary and secondary prophylaxis for MAC.
This agent had a new dosage form recently approved that allows it to be given once daily and it also causes Qtc prolongation.
This agent causes dizziness and vertigo which limits it use.
The macrolides can overcome penicillin resistant S. pneumoniae because of the predominance of this type of resistance mechanism in the US
efflux or mef A gene. This is more predominant in the US than the erm (B) gene which results in methylation of an adenine residue on the 23S rRNA by a methylase enzyme (irreversible)
This anti-fungal agent is the result of an old agent with new technology to deliver a higher dose with fewer side effects.
liposomal or lipid complex amphotericin
This antibiotic is a combination product for the treatment of vancomycin resistant Enterococcus Faecium.
quinapristin/dalfopristin (Synercid)
This agent is active against most resistant gram positive organisms including MRSA and is available in both oral and parenteral forms.
linezolid (Zyvox)?
This older class of antibiotics has recently seen a revival for the treatment of highly resistant acinetobacter.
polymyxins (polymyxin B and colistin)
This parenteral antibiotic is used to treatment complicated skin and skin structure infections caused by susceptible strains of gram positive organisms including MSSA and MRSA and has a dose related myopathic toxicity.
This drug was approved by the FDA in February 2006 for the treatment of esophageal candidiasis. It is a lipopeptide with greater activity than amphotericin and fluconazole against C. albicans, C. tropicalis, C. glabrata, and C. krusei.
anadulafungin (Eraxis®)