Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
24 Cards in this Set
- Front
- Back
|
CC/HPI
|
Subjective
|
|
|
PMH
|
Subjective
|
|
|
Drug Hx
|
Subjective
|
|
|
Family/Social Hx
|
Subjective
|
|
|
ROS
|
Subjective
|
|
|
Objective data
|
Objective
|
|
|
Problem list
|
Assessment
|
|
|
Assessment of problem
|
Assessment
|
|
|
Therapeutic objective(s)
|
Assessment
|
|
|
Assessment of therapy
|
Assessment
|
|
|
Patient-related variables
|
Assessment
|
|
|
Agent-related variables
|
Assessment
|
|
|
Treatment recommendation
|
Plan
|
|
|
Referral/Triage plan
|
Plan
|
|
|
Monitoring for efficacy
|
Plan
|
|
|
Monitoring for efficacy
|
Plan
|
|
|
Patient education
|
Plan
|
|
|
Lactic acidosis
|
Symptoms:
Fatigue, malaise, weakness GI complaints Anorexia, N, V, D Abdominal pain and distention Dyspnea Cardiac arrhythmia Multi-organ failure Death Caused by NRTI's. Abacavir and tenofovir are least likely to cause it. |
|
|
Pancreatitis
|
Risk factors:
Alcoholism Hypertriglyceridemia Obesity Gallstones Drugs--pentamadine Caused by NRTI's. Most associated with didanosine and stavudine. |
|
|
Hepatic Steatosis
|
Fatty liver.
Occurs with all NRTI's. GI: anorexia, N,V, Abd. Pain, ascites Encephalopathy Dyspnea Death Caused by all NRTI's. |
|
|
Peripheral neuropathy
|
Tx by lowering dose or d/c offending agent
Treat symptoms NSAIDS, APAP TCA, gabapentin, lamotrigine HIV, alcohol, diabetes, nutrition, other drugs may contribute May take months to resolve Less common today due to decrease use of offending agents Caused by NRTI's. Most associated with didanosine and stavudine. |
|
|
Myopathy
|
Fatigue, myalgia, proximal weakness and wasting
Inc. CPK levels Abnormal mitochondria Incidence 5-20% assoc with long tx Zidovudine and other NRTI's Cardiomyopathy: <1% incidence |
|
|
Hypersensitivity Reactions (HSR)
|
Rash, fever, mayalgia, arthralgia, fatigue, mucosal blistering and ulceration, stevens-johnson syndrome, toxic epidermal necrolysis, hypotension
100x more common in HIV patients Abacavir, amprenavir, all NNRTIs Occurs early in tx; about 50% resolve on continuing therapy. Nevirapine>Efavirenz. Abacavir: If fever is present, d/c and DO NOT RECHALLENGE (can cause death). |
|
|
Lipodystrophy
|
Syndrome
Fat accumulation: buffalo hump, inc. abdomen, inc. breast size; Lipoatrophy: facial atrophy,peripheral atrophy; dec. weight, profound buttock wasting; is not muscle wasting Metabolic changes: glucose intol, inc. LDL,dec.HDL, inc TG NRTIs mitochondria toxicity(stavudine and didanosine worse); PIs insulin resistance = multi drug etiology Change medications Substitute stavudine with zidovudine or abacavir Plastic surgery--$$$ Antidiabetic therapy Anabolic steroids; growth hormone Prevention:vitamins, antioxidants? Most interventions not proven Very difficult to treat |
