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9 Cards in this Set

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What is irritable bowl syndrome?

Is a functional GI disorder that is characterised by abdominal pain and disordered defecation. there is no biological marker/signs that can point to a diagnosis

What are the typical signs and symptoms of IBS?

Think ABC


A. Abdominal pain: varied locations and relieved by defecation or passing wind


B. Bloating: is usually worse by the end of the day and produces offensive wind


C. Change of bowl habits: diarrhoea or constipation or a mixture of both


Mental health: 40-60% of people suffering IBS have anxiety or depression

How is the diagnosis of IBS achieved?

Hard to diagnose due to lack of biological marker.


The symptoms must be in the Rome III criteria for IBS which include:


-Recurrent abdominal pain or discomfort and a marked change in bowel habit in the last 6 months


With 2 more of the following:


- Pain is relieved by defecation


- Onset of pain is associated with a change in frequency of stools


- Onset of pain is associated with a change in the appearance of stools.

What are the 3 sub classifications of IBS?

1. Diarrhoea predominant D-IBS


2. Constipation predominant C-IBS


3. Pain predominant P-IBS

What are the alarm sympotoms for IBS?


i.e. symptoms that indicated a condition other than IBS

- Onset of symptoms later in life (40+)


- Frequent nocturnal waking with symptoms


- family history of colon cancer, IBD


- Recurrent vomiting


- Persistent diarrhoea


- Sever constipation


- Rectal bleeding


- Fever


- Unexplained weight loss

What is the treatment of P-IBS?

Anti-spasmotic agent:


Hyoscine butylbromide 20mg qid OR Mebeverine 135mg tds OR Peppermint oil 0.2ml/cap - 2 caps tds


Antidepressants:


TCA - also have anticholinergic properties which may reduce diarrhoea


Amitriptyline OR nortryptline 12.5-25 mg nocte then slowly increase


SSIR- rarely used no real evidence


Citalopram 20mg d

What is the treatment of C-IBS?

Fibre products:


- Methylcellulose, psyllium, course bran


- May aggravate symptoms initially, start small and build up over 3-4 weeks


Osmotic laxitives:


- Lactulose, sorbitol


Stimulants


- Senna

What is the treatment of D-IBS?

Use agents that slow colinonic transit


- Loperamide 4-8mg dd MAX 16mg daily


- Diphenoxylate 2.5mg/atropine 25mcg 2 tablets tds to qid


Can trial increasing the consumption of feed that produce faecal mass

What is the treatment for IBS when the primary complaint is bloating?

Anticholinergic agents


hyoscyamine butylbromide 20mg qid


lifestyle changes:


consume low gas producing foods


low FODMAP diet