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21 Cards in this Set
- Front
- Back
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What is the mechanism of action of the OCP?
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To mimic the sequence and relative levels of oestrogen and progesterone thru a menstrual cycle
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What are some uses for the OCP?
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Contraception
Menstrual disorders Prevent/reduce PMS Emergency contraception |
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What the progesterone norethisteone used for?
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Beneficial for women with excess reactions to oestrogen
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What is the progesterone cyproterone used for?
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Beneficial for women with oily skin, acne, hirsutism or breakthrough bleeding
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What is the formulation for the monophasic OCP?
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Fixed ratio oestrogen:progesterone for 21/28 days
eg Brenda |
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What is the formulation for the biphasic OCP?
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Oestrogen levels are constant but low progesterone in day 7-11 and high on day 11-14
eg Biphasil |
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What is the formulation for triphasic OCP?
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Oestrogen levels consistantly low while progesterone is progressively phased up
eg Triphasil |
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What is the formulation for the mini pill?
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Progesterone only 28/28 days
eg Microval good to use with smokers |
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What are the general adverse effects for the OCP?
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Suppression of normal physiological pathways
Depletion of B group vitamins |
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What are the routes of administration for HRT?
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Oral
Transdermal patches Oestrogen implants Testosterone implants Tibolone Topical oestrogen |
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What are some side effects from oestrogen HRT?
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Breast tenderness
Fluid retention Nausea Headache Leg cramps Increased risk of thrombosis |
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What are some side effects from progesterone HRT?
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Breast tenderness
Pelvic discomfort Psychological symptoms Decreased libido Menstrual bleeding |
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What are the drug therapies for the treatment of osteoporosis?
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HRT
Nutritional therapies Calcitonin Bisphosphonates SERMs |
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What is the mechanism of action of bisphosphonates?
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They are potent inhibitors of osteoclastic medicated bone resorption.
they bind to hydoxyapatite crystals and become a permanant part of bone structure |
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What are some side effects of bisphosphonates?
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Dyspepsia
Nausea Vomiting Gastritis Abdominal pain Dirrhoea Hypocalcaemia Rash Headache |
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What is the mechanism of action of SERM's?
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They decrease bone resorption and increase bone mineral density and they have a favourable effect of CVD
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What are some adverse effects of SERM's
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Hot flushes
Leg cramps |
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What are herbs that are used for hormone regulation?
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Chaste tree
Licorice Dong quai Black cohosh Wild yam False unicorn root Shatavari Wild peony Tribulus Zizyphus Damiana |
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What nutritional therapies are good for female repro disorders?
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OCP - B group vitamins
PMS - Fish oil, B6, E, Mg, Zn Menopause - Fish oil. B group. Mg, Ca, Zn, E, C, taurine, tryptophan Osteoporosis - Ca, D, Mg, K, boron, folic acid, B6, B12 |
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What are some herb/drug interactions with OCP?
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Chaste treet - reduced herb effects
Licorice - increase adverse effects SJW - reduced drug effects |
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What are some nutrient/drug interactions with OCP?
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Vit A - OCP increases levels
Folate - decreases levels, supplement B group - decrease levels, supplement |
