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43 Cards in this Set
- Front
- Back
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CAUSES OF INTERSTITIAL DISEASE
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DRUGS, AUTOIMMUNE, INHALED DUST, CERTAIN INFECTIONS, BUT MOST HAVE NO IDENTIFIABLE CAUSE
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FEATURES COMMON TO INTERSTITIAL DISEASE
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INFLAMMATION AND FIBROSIS OF THE INTERALVEOLAR SEPTUM (ALVEOLITIS)
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DISEASE PROCESS THAT IS OFTEN CHRONIC AND CAN LEAD TO IRREVERSIBLE INTERSTITIAL FIBROSIS THAT CAUSES DERANGEMENT OF GAS EXCHANGE I.E. DECREASE IN DLCO AND VENTILATORY FUNCTION
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INTERSTITIAL DISEASE
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SYMPTOMS OF INTERSTITIAL DISEASE
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EXERTIONAL DYSPNEA AND DRY COUGH OF INSIDIOUS ONSET; DIGITAL CLUBBING IS COMMON
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LUNG'S ABILITY TO TAKE UP AN INHALED NONREACTIVE TEST GAS, SUCH AS CO, THAT BINDS TO HEMOGLOBIN; CO WILL REACH ALVEOLAR SPACE AND BE EXHALED
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CARBON MONOXIDE DIFFUSING CAPACITY(DLCO)
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CXR OF INTERSTITIAL DISEASE
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GROUND GLASS, NODULAR, RETICULAR, OR RETICULONODULAR INFILTRATES THAT MAY PROGRESS TO HONEYCOMB LUNG
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HONEYCOMB LUNG- WHAT CONDITION?
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INTERSTITIAL DISEASE
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PATHOLOGICAL DIAGNOSIS OF INTERSTITIAL DISEASE
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LUNG BIOPSY
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MOST COMMON DIAGNOSIS PRESENTING WITH INTERSTITIAL LUNG DISEASE
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CRYPTOGENIC FIBROSING ALVEOLITIS (IDIOPATHIC PULMONARY FIBROSIS)
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AGE OF ONSET AND SYMPTOMS WITH CRYPTOGENIC FIBROSING ALVEOLITIS
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AGE 60-70 WITH INSIDIOUS ONSET OF COUGH AND DYSPNEA MONTHS OR YEARS IN DURATION; MORE MEN THAN WOMEN; MAY BE SMOKING RELATED
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TX FOR CRYPTOGENIC FIBROSING ALVEOLITIS
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SUPPORTIVE CARE, SUPPLEMENTAL O2, AND CORTICOSTEROIDS ; HEART-LUNG AND LUNG TRANSPLANT FOR SELECTED PTS
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PROGNOSIS FOR CRYPTOGENIC FIBROSING ALVEOLITIS
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5 YR SURVIVAL OF 50%
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SYSTEMIC DISEASE OF UNKNOWN CAUSE WITH GRANULOMATOUS INFLAMMATION OF THE LUNG IN 90% OF PATIENTS
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SARCOIDOSIS
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S/S OF SARCOIDOSIS
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MALAISE, FEVER, DYSPNEA WITH INSIDIOUS ONSET; MAY ALSO HAVE SYMPTOMS OF SKIN, EYES, PERIPHERAL NERVES, LIVER, KIDNEY, OR HEART
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PHYSICAL FINDINGS OF OTHER AREAS OF SARCOIDOSIS
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SKIN RASH, ERYTHEMA NODOSUM, PAROTID GLAND ENLARGEMENT, HEPATOSPLENOMEGALY, LYMPHADENOPATHY
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GROUPS MOST AFFECTED BY SARCOIDOSIS
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BLACKS (ESP WOMEN) AND NORTHERN EUROPEAN WHITES
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WHERE ARE FIRST SIGNS OF SARCOIDOSIS OFTEN FOUND?
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ON ROUTINE CXR WITH BILATERAL HILAR AND PARATRACHEAL LYMPHADENOPATHY
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TX FOR SARCOIDOSIS
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ORAL CORTICOSTEROIDS FOR SYMPTOMATIC LESIONS AND ALSO CONSTITUTIONAL SYMPTOMS- HYPERCALCEMIA, IRITIS, ARTHRITIS, CENTRAL NERVOUS SYSTEM INVOLVEMENT, GRANULOMATOUS HEPATITIS, AND CUTANEOUS LESIONS
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AN IDIOPATHIC DISEASE HITTING IN COMBO W/ GLOMERULONEPHRITIS, NECROTIZING GRANULOMATOUS VASCULITIS OF UPPER AND LOWER RESPIRATORY TRACTS, AND VARYING DEGREES OF SMALL VESSEL VASCULITIS
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WEGENER'S GRANULOMATOSIS
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POP. USUALLY AFFECTED BY WEGENER'S GRANULOMATOSIS
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YOUNG OR MIDDLE AGED ADULTS
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IDIOPATHIC MULTISYSTEM VASCULITIS OF SMALL AND MEDIUM SIZED ARTERIES THAT OCCURS IN PATIENTS WITH ASTHMA
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CHURG-STRASS SYNDROME
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TX FOR WEGENER'S GRANULOMATOSIS AND CHURG-STRUASS SYNDROME
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CORTICOSTEROIDS, BUT CAN BE DEVASTATING WITH IRREVERSIBLE LUNG INVOLVEMENT
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GOODPASTURE'S SYNDROME
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IDIOPATHIC RECURRENT ALVEOLAR HEMORRHAGE AND RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS
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POP. MOST AFFECTED BY GOODPASTURE'S
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MEN WHO ARE IN THEIR 30S AND 40S
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PRESENTING SYMPTOM OF GOODPASTURE'S
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HEMOPTYSIS
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HOW DO WE MAKE THE DIAGNOSIS OF GOODPASTURE'S?
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CHARACTERISTIC LINEAR IGG DEPOSITS IN GLOMERULI AND PRESENCE OF ANTI-GLOMERULAR BASEMENT MEMBRANE ANTIBODY IN SERUM
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TX OF GOODPASTURE'S
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IMMUNOSUPPRESSIVE DRUGS AND PLASMAPHERESIS; CONTROLLABLE USUALLY BUT GREATLY IMPACTS QUALITY OF LIFE
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HISTOPLASMOSIS IS LINKED TO WHAT
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BIRD DROPPINGS AND BAT EXPOSURE
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SYMPTOMS AND CXR EVIDENCE OF HISTOPLASMOSIS
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MAY BE ASYMPTOMATIC OR SHOW MILD RESPIRATORY OR FLU LIKE ILLNESSES IN NONCOMPROMISED PATIENTS; IN COMPROMISED PATIENTS, USUALLY PRESENTS AS ATYPICAL PNEUMONIA; PAST INFECTION WILL LEAD TO CALCIFICATIONS ON CXR
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DRUG TX FOR AIDS-ASSOCIATED HISTOPLASMOSIS
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AMPHOTERICIN, ITRACONAZOLE, FLUCONAZOLE- USED FOR ACUTE AND MAINTENANCE THERAPY; KETONAZOLE ALSO USED FOR MAINTENANCE
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THIS IS ENDEMIC IN SOIL OF ARID REGIONS OF US, MEXICO, AND S. AND C. AMERICA
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COCCIDIOIDMYCOSIS
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SYMPTOMS OF COCCIDIODMYCOSIS
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FLU LIKE W/ MALAISE, FEVER, BACKACHE, AND COUGH; CAN ALSO CAUSE ARTHRALGIA, PERIARTICULAR SWELLING OF KNEES AND ANKLES, AND ERYTHEMA NODOSUM
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ERYTHEMA NODOSUM
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Inflammatory disorder that is characterized by
tender, red nodules under the skin. |
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VERY COMMON OPPORTUNISTIC INFECTION IN HIV-INFECTED PATIENTS IN ENDEMIC AREAS
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COCCIDIOIDOMYCOSIS
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THIS INFECTION OCCURS MOST COMMONLY IN MEN OF THE SOUTH CENTRAL AND MIDWEST USA AND CANADA
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BLASTOMYCOSIS
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THIS PULMONARY INFECTION IS OFTEN ASYMPTOMATIC, BUT IF DESSIMINATED, THERE WILL BE SKIN LESIONS WITH VERRUCOUS CUTANEOUS LESIONS WITH ABRUPT DOWNSLOPING BORDER
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BLASTOMYCOSIS
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BESIDES THE LUNGS AND SKIN, WHAT SYSTEMS CAN BLASTOMYCOSIS AFFECT?
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BONE AND UROGENITAL SYSTEM
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VERRUCOUS
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WART LIKE
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ASPERGILLOSIS CAN CAUSE ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS- what are the symptoms?
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LEADS TO WHEEZING AND TRANSIENT INFILTRATES
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THIS CONDITION CAN COLONIZE THE BRACHIAL; USUALLY ASYMPTOMATIC UNLESS THERE IS IMMUNOCOMPROMISE
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ASPERGILLOSIS
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WHEN A PATIENT WITH A HISTORY OF ASTHMA DEVELOPS WORSENING SYMPTOMS WITH FLEETING INFILTRATES ACCOMPANIED BY EOSINOPHILIA, HIGH LEVEL OF IGE, AND BROWN FLECKED SPUTUM
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ALLERGIC BRONCHOPULOMARY ASPERGILLOSIS
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TX FOR ACUTE EXACERBATIONS OF ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS
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ORAL PREDNISONE OFTEN CONTROLS CLINICAL SYMPTOMS- MAY NEED FOR WEEKS TO MONTHS; BRONCHODILATORS
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BROWN FLECKED SPUTUM
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ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS
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