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41 Cards in this Set
- Front
- Back
Anything that goes wrong with a newborn should make you think of ____________.
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sepsis (3 things no matter how minor--> treat like sepsis)
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Risk factors for sepsis
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prematurity (6x greater), prolonged rupture of membrane (PROM), Maternal Group B Strep (GBS) colonization
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Etiology of sepsis in newborn
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GBS, E. coli, Listeria monocytogenes, Staphylococcus (usually late onset)
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Incidence of sepsis
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0.50%
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Clinical presentation of sepsis in babies 1-7 days old
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usually infant declines rapidly; fever, hypotonia, hypotension, resp. distress if pneumonia is present
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Clinical presentation of sepsis in babies over 7 days old
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usually more insidious onset, fever, poor feeding, lethargy, more likely associated with meningitis
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W/up when sepsis is suspected?
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CBC, BC times 2, UA, UC, and glucose; CXR if resp. sxs, consider lumbar puncture
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Tx for sepsis in newborn
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IV ampicillin and gentamycin after workup drawn and await culture results in 48 hours
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When do you consider adding Vancomycin for sepsis in newborn?
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if late onset and/or meningitis present
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If sepsis is confirmed by culture, how many days do you treat?
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14 days
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If meningitis is confirmed by culture, how many days do you treat?
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21 days
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MC cause of newborn sepsis
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GBS
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Herpes- more likely early or late onset sepsis?
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later onset
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Normal white count in baby
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18-30,000
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Normal H and H in baby
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Hematocrit close to 60
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What is "full eval" in GBS Positive mother?
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CBC, BC times 2, UA, UC, and glucose; CXR if resp. sxs, consider lumbar puncture
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What is "limted eval" in GBS Positive mother?
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CBC, BC X2
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MC pathway for sepsis
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respiratory distress
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Common causes of respirastaory distress in preterm infants
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sepsis/pneumonia; Respiratory Distress Syndrome (RDS), and apena of prematurity
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Common causes of respiratoty dstress in term infants
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sepsis/pneumonia; meconium aspiration syndrome, transent tachypnea of the newboen, primary persistant pulmonary hypertention (PPHN)
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Transient tachypnea of the newborn
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diagnosis of exclusion
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Result of Respiratory Distress Syndrome
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end expiration atelectasis
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CXR appearance with Respiratory Distress Syndrome
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bilateral "ground glass" appearance
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This condition is as a result of insufficient surfactant productinon by Type II pneumatocytes
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Respiratoy Distress Syndrome
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What do type II pneumotocytes make?
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surfactant
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Tx of respiratory distress syndrome.
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maternal steroids prior to deliver, intubation and resp. support, and artificail surfactant via ET tube
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When is insufficient surfactant production commonly seen?
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less than 34 weeks
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Complications of RDS?
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persistent patent ductus arterious; oxygen to
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What are the two types of oxygen toxicity in RDS?
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bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP)
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Two classes of causes of apnea
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central and peripheral
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What happens in central apnea?
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medulla and pons don't stimulate the phrenic nerve
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What happens in peripheral apnea?
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airway obstruction due to malformation or positioning
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Which is most common- central or peripheral apnea?
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central
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Tx for apnea of prematurity
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oxygen, stimulants (caffeine*** or theophylline), anemia correction
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How is caffeine given to babies?
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as they outgrow their dose, we see if they are able to breath on their own; if they don't breath, we up the dose after helping them to breath; eventually they outgrow it
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Chemical burns due to meconium predispose the baby to ___________ infections, most commonly Group b strep.
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bacterial (takes hold due to damaged tissue)
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What is seen on chest xray of MAS?
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coarse, irregular infiltrates
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Retained amniotic fluid causes mild hypoxia shortly after birth with resolution in 24 hours
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Transient Tachypnea of the Newborn
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What does CXR in TT of newborn show?
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fluid in fissures
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What infants are more likely tohave Transient Tachypnea of the Newborn?
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more common in C section, LGA infants
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Explain primary pulmonary hypertension as a cause of respiratory distress in term babies.
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hypoxia without evidence of structural cardiac or pulmonary disease usually as a result ot another process such as PFO, PDA
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