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41 Cards in this Set

  • Front
  • Back
Anything that goes wrong with a newborn should make you think of ____________.
sepsis (3 things no matter how minor--> treat like sepsis)
Risk factors for sepsis
prematurity (6x greater), prolonged rupture of membrane (PROM), Maternal Group B Strep (GBS) colonization
Etiology of sepsis in newborn
GBS, E. coli, Listeria monocytogenes, Staphylococcus (usually late onset)
Incidence of sepsis
0.50%
Clinical presentation of sepsis in babies 1-7 days old
usually infant declines rapidly; fever, hypotonia, hypotension, resp. distress if pneumonia is present
Clinical presentation of sepsis in babies over 7 days old
usually more insidious onset, fever, poor feeding, lethargy, more likely associated with meningitis
W/up when sepsis is suspected?
CBC, BC times 2, UA, UC, and glucose; CXR if resp. sxs, consider lumbar puncture
Tx for sepsis in newborn
IV ampicillin and gentamycin after workup drawn and await culture results in 48 hours
When do you consider adding Vancomycin for sepsis in newborn?
if late onset and/or meningitis present
If sepsis is confirmed by culture, how many days do you treat?
14 days
If meningitis is confirmed by culture, how many days do you treat?
21 days
MC cause of newborn sepsis
GBS
Herpes- more likely early or late onset sepsis?
later onset
Normal white count in baby
18-30,000
Normal H and H in baby
Hematocrit close to 60
What is "full eval" in GBS Positive mother?
CBC, BC times 2, UA, UC, and glucose; CXR if resp. sxs, consider lumbar puncture
What is "limted eval" in GBS Positive mother?
CBC, BC X2
MC pathway for sepsis
respiratory distress
Common causes of respirastaory distress in preterm infants
sepsis/pneumonia; Respiratory Distress Syndrome (RDS), and apena of prematurity
Common causes of respiratoty dstress in term infants
sepsis/pneumonia; meconium aspiration syndrome, transent tachypnea of the newboen, primary persistant pulmonary hypertention (PPHN)
Transient tachypnea of the newborn
diagnosis of exclusion
Result of Respiratory Distress Syndrome
end expiration atelectasis
CXR appearance with Respiratory Distress Syndrome
bilateral "ground glass" appearance
This condition is as a result of insufficient surfactant productinon by Type II pneumatocytes
Respiratoy Distress Syndrome
What do type II pneumotocytes make?
surfactant
Tx of respiratory distress syndrome.
maternal steroids prior to deliver, intubation and resp. support, and artificail surfactant via ET tube
When is insufficient surfactant production commonly seen?
less than 34 weeks
Complications of RDS?
persistent patent ductus arterious; oxygen to
What are the two types of oxygen toxicity in RDS?
bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP)
Two classes of causes of apnea
central and peripheral
What happens in central apnea?
medulla and pons don't stimulate the phrenic nerve
What happens in peripheral apnea?
airway obstruction due to malformation or positioning
Which is most common- central or peripheral apnea?
central
Tx for apnea of prematurity
oxygen, stimulants (caffeine*** or theophylline), anemia correction
How is caffeine given to babies?
as they outgrow their dose, we see if they are able to breath on their own; if they don't breath, we up the dose after helping them to breath; eventually they outgrow it
Chemical burns due to meconium predispose the baby to ___________ infections, most commonly Group b strep.
bacterial (takes hold due to damaged tissue)
What is seen on chest xray of MAS?
coarse, irregular infiltrates
Retained amniotic fluid causes mild hypoxia shortly after birth with resolution in 24 hours
Transient Tachypnea of the Newborn
What does CXR in TT of newborn show?
fluid in fissures
What infants are more likely tohave Transient Tachypnea of the Newborn?
more common in C section, LGA infants
Explain primary pulmonary hypertension as a cause of respiratory distress in term babies.
hypoxia without evidence of structural cardiac or pulmonary disease usually as a result ot another process such as PFO, PDA