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89 Cards in this Set
- Front
- Back
Drugs treating open-angle glucoma
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B-antagoinsts--
betaxolol. levobetaxolol levobunolol, carteolol, and timolol |
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Drugs for prophylaxis of migrane
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NAP MT
Nadolol, atenolol. propranolol. metoprolol. and timolol |
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What drugs treated BPH
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Alpha 1 antagoinst
Alfuzosin, tamsulosin, and terazosin |
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How is acute MI treated earlt
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atneolol. and metoprolol
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What drug is used in hyperthroidism
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propranolol
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Uses of Dopamine
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Shock--high doses adrenergic agoinst---(non-selective adregenric agoisnt
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Uses of Epinehprine
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Caradic arrest adn allaergic reactions (NON-selective adrenergic agoinsts
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Uses of methoxamine and phenylephine
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paroxysmal arterial tachycardia (alphfa agonist
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Phenoxybenzamine
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phaeochromocytoma
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Yohimbine
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A2 receptor antagoinst
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acebutolol
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B1-selective ANTAGOINST
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alfuzosin
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A1-selective antagoinst---treating BPH
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atenolol
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B1-seceltive antagoinst-acute MI
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Betaxolol
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Beta-antagoinst--used in open-angle glucoma
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Cartelol
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Non-selective Beta-antagoinst--parital agoinst
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Cavediolol
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Non-selective B antagoinst--and alpha 1 antagoinst
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Doxazosin
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Alpha 1-selective antagoinst
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esmolol
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Selective B-1 antagoinst--short DOA, rapidily hydrolyzed by esterase, B-short used
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Labetolol
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Non-selective B-antagoinst, selective Alpha 1 antagoinst
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Levobetaxolol
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B-antagoinst--used in open angle glucoma
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Metoprolol
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Non-selective beta antagoinst-early MI with ateneolol
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Nadolol
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beta antagoinst--migraines
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Penbutolol
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Non-selective beta antagoinst, partial agonist
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Pehnoxybenzamine
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Non-selective alpha antagoisnt-irrversible, and inbibits muscarinic H1
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Pehntoloamine
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Non selective alpha antagoinst-inhbit muscarinic H1
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Pindolol
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Non-selective beta antagoinst partial agoinst
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Prazosin
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Alpha 1 sective antagoinst
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Proranolol
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Non-selective B- antagoinst
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Tamusulosin
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Alpha 1 antagoinst-inhbit A1A prostate gland used in BPH
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Terazosin
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Alpha 1 antagoinst used in BPH
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Timolol
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Non-selective beta antaoingst used in open-angle glucoma and mirgrane prophylaxics
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tetrodotoxin
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blocks "fast" Na+ channels prevents AP conduction
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w-conotoxin
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blocks N-type Ca+2 channels--prevents NT release
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Botulinum toxin A
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binds to synaptobreven--inbhit Ach release-and paralysis of SKM
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A-Latrotoxin
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promotes Ca++ influx into nerve termin, causing massive ACh release, followed by cholinergic transmission failure
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acethlchoine
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actived muscarinic and nicotinic receptors
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atropine
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Muscarinic antagoinst--parasymthatic
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Botulimunm toxin
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inhibitor of release--binds ot synaptobrevin--inbhits Ach from binding,and muscle paraylis
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w-conotoxin
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inhibitis N-type Ca+ channels prevents release of Ach
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Hexamethonium
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NN-- blocks all autonomic bloackage
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a-latrotoinx
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increase Ca+ influx into cell--massive release of Ach--followoed by cholineric failur
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tetrodotoxin
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blocks "fast" Na+ channels prevents AP conduction
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w-conotoxin
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blocks N-type Ca+2 channels--prevents NT release
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Botulinum toxin A
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binds to synaptobreven--inbhit Ach release-and paralysis of SKM
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A-Latrotoxin
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promotes Ca++ influx into nerve termin, causing massive ACh release, followed by cholinergic transmission failure
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acethlchoine
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actived muscarinic and nicotinic receptors
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atropine
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Muscarinic antagoinst--parasymthatic
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Botulimunm toxin
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inhibitor of release--binds ot synaptobrevin--inbhits Ach from binding,and muscle paraylis
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w-conotoxin
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inhibitis N-type Ca+ channels prevents release of Ach
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Hexamethonium
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NN-- blocks all autonomic bloackage
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a-latrotoinx
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increase Ca+ influx into cell--massive release of Ach--followoed by cholineric failur
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Muscarine
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activate all muscarinic
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Neostigmine
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indiriecly acting choliommmetic, increasing Ach--enchanes para/somatic
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Nicotine
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activates Nn and NM receptors
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Acethlcholine inhbitors
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M2
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Opitaes
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U
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Norepinephrine
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A2
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Tetrodotoxin
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inhibts fast acting Na+ channels inhbit AP
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Tubocurarine
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NM--paralysis of muscle
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acetylcholine
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Muscarinic and nicotinic agoinst
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Atropine
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muscarinic antagoinst (parsymthatic)
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Botulinum Toxin
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binds to synaptobrevin and prevents Ach release, and muscle paralysis--thearputic--obrital msucle for spasmotic/dytonic, cosmetic, sweating, migraines, and muscle dsytonic
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W-conotoxin
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blocks N-type Ca+ channels, prevents Ach release
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Hexamethonium
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NN--blocks autonomic transmission
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Nicotine
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Activates Nicotinic receptors
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Tetrodotoxin
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blocks Fast Na channels, prevents AP
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Tubocurarine
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NM--paralysis
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Aceclidine
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Cloolinommetic with muscarinic and nicotinic activity
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Ambedonium
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reversible cholinesterase inbhitior (use in myastensia gravis
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bethanechol
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Cholinommmetic--unirary retnetion, and GI atony
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Carbachol
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muscasic and nicotrinic acity--cholinomimetics GI=Bladder>eye>CV
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cevimeline
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cholinomimetic--xerostoma
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Demecarium
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Cholinesterase inbhitor--longer acting--used with open angle glucoma--can cause cataract with increase useage
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DFP
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irrversible cholinsterase inbhiote, highly voltility and higly lipid solulbe
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Donzepril
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Cholinertase inbhitior reversible--lipid solble enters CNS
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Echothiophate
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irrversible-safest to use--used in open angled glucoma,
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edrophonium
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reversible cholinesterase inbhibitor-short acting, used for daignosis of myasthenia gravis--
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Galantamine
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revisible cholinestase inbhitior--lipid soluble enters CNS
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Malathion
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Irrversible inbhitior of cholisterases--active metabolite, insectidcie, and rapidly metabolized in vertebrae
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Methacholine
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Diganosis of Bronchial provocation test--muscarinicn
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muscarine
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cholinommetic--muscarinic acitivty
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Neostigmine
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Choinesteraser reversible inhibitor GI atony, and bladder , Myasenetia gravis
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Obidoxmine
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cholinesterase reactivator
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Parathion
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insecidice lipid souble irreversible inhbitor pro-drug convered to paraoxan
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Physosotigmein
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open-angle glucoma and narrow angled glucomsa lipid soluble so outcomepes muscarninc antagoinsts
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Pilocarpine
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cholinommetic--excessive sweating--treatmenat of xerostomia
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Pralidoxamine
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cholinesterase reactivtors
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Pyridostigmine
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cholinesterase inihbitior for myastnesia gravis
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Rivistigmine
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reversible inbhitiorof cholinesterase---lipid soluble
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