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61 Cards in this Set

  • Front
  • Back

Physiology

Study of how body maintains homeostasis

Homeostasis

All the changes that occur in the body to keep functions within normal ranges

Systems that regulate homeostasis

Nervous System


Endocrine system

Important Vital Signs

Heart Rate


Respiration Rate


Blood O2/CO2


Blood Pressure


Blood Glucose


Body Temp.


Etc.


-the body tries to get these back to normal

Homeostasis components

Stimulus


Sensor (receptor)


Integrating center


Effector


Response (effect)

Stimulus

a change in a body function, usually outside the normal range

sensor (receptor)

detects this change. sends signal to integrating center (brain)

integrating center

where sensory info is interpreted, compared to a "set point" or normal range for that body function. responds by sending a command (nervous or endocrine).

effector

muscle or gland that responds to the command.


Voluntary muscle or cardiac or smooth muscle.

Effect response

usually reverses the initial change in body function if negative feedback loop

Positive feedback loop

rare feedback system in the body


when change occurs body responds by causing more of that change, amplifies the effect


-nursing a child


-birthing a child

Negative feedback loop

most common feedback system


when change occurs, body responds by reversal of the change, reverses the effect


-most processes in the body

Nursing & Oxytocin release

positive


-stimulus-baby sucking on nipple


-sensor-tactile receptors in nipple


-integrating center-hypothalamus


-effector-supraoptic and paraventricular nucleus secrets oxytocin


-effect-milk release from the breast


=as long as baby is nursing, oxytocin is released


=when nursing stops, oxytocin release stops

Birth & Oxytocin release

positive


-stimulus-stretch receptors stretch cervix


-sensor-stretch receptors in the cervix


-integrating center-hypothalamus


-effectors-supraoptic and paraventricular nucleus secretes oxytocin


-effect-strong uterin muscle contraction


=squeezes baby more against cervix


=cervix stretch receptors activated more


=more oxytocin released


=this continues until stimulus is gone, baby has been born

Body Temperature

Negative


-Body temp set point of about 98.6F


-97.6-99.6F


-stimulus-body temp decreases or increases outside the normal range


-sensors-thermoreceptors


-integrating center-hypothalamus (anterior nucleus)


-effectors-if body temp is too high, sweat glands; if body temp is too low, skeletal muscles


-effect-return body temp to normal

Regulation of blood glucose

Negative


-stimulus-blood glucose outside normal range


-sensor, integrating center, effector-pancreas


-depending on blood glucose levels pancreas secrete: if blood glucose too high-beta cells secrete insulin-tells the body cells to take up blood glucose so that it will decrease; if blood glucose too low-Glucagon-tell the liver to break down glycogen to glucose and release, by the liver, to bloodstream to increase blood glucose


-effect-blood glucose remains stable

Blood Pressure Change/with Posture

Negative


-stimulus-B.P is out of normal range


-sensors-arteries closest to heart, aortic arch and carotid arteries baroreceptors stretch receptors


-integrating center-medulla oblongata


-effectors-heart


-effect-increased or decreased heart rate

pH

numerical scale 0-14


<7=acidic, more H+ ions


7=neutral


>7=alkaline, fewer H+ ions

the importance of pH

shapes/functions of molecules


enzyme activity


most chemical reactions in body


ability of molecules to dissolve in water

blood pH range=7.35-7.45

acidosis-blood pH below 7.35


alkalosis-blood pH above 7.45

blood pH outside normal range interferes with:

-hemoglobin's oxygen carrying capacity


-functions of enzymes


-chemical reactions involved in homeostasis

Organ systems that regulate blood pH

1. Lungs fastest to regulate blood pH


2. Kidneys


3. Liver

Major organic compounds

1. carbohydrates-pastas, wheat, etc


2. lipids-butter


3. protein-meat


4. nucleic acids-DNA and RNA

Carbohydrates

Simple carbohydrates


-monosaccharide, single sugar unit, glucose, galactose, fructose


-disaccharide, 2 sugar units, sucrose, lactose, maltose


complex carbohydrates


-polysaccharides-more than w sugar units,


=starch-potatos, rice, bread


=cellulose-plants, indigestible


=glycogen-storage form of cellulose in liver and also skeletal muscles

Lipids

1. Fats-triglycerides, or fatty acids


-saturated fats-heart unhealthy animal based fats, solid at room temp


-unsaturated fats-heart healthy plant based fats, liquid at room temp


-trans fats-very heart unhealthy


2. phopholipids-cells phospholipid membrane


3. ketones


=use of ketones for energy is called ketosis


=a drop in blood pH from metabolizing ketones called ketoacidosis


4. prostaglandins-lipid based hormone funcitons in inflamation responsible for menstral cramps


5. steroids-hromones lipid based

steroids

testosterone, estrogen, progesterone, cortisol


exogenous steroid-steroid outside body


-anabolic steroids-synthetic testosterone


-birth control hormones-estrogen and progesterone


-anti inflammatory steroids-corticosteroids, hydrocortisone, prednisone, and prednisolone




endogenous steroids-steroid that the body produces, cholesterol


-natural cortisol, testosterone, estrogen, progesterone

proteins

protein structure determines how proteins function


enzymes-proteins that catalyze chemical reactions


hemoglobin-protein pigment that carries O2


Insulin and glucagon


antibodies-immune function


acid phosphatase-protein that can show prostate cancer


creatine phosphonkinase CPK-enzyme when high in blood can b associated with heart, brain, and muscle damage

protein disorders

cystic fibrosis-chronic mucous in the lungs due to a homozygous recessive disorder of a protein on alveolar cells


sickle cell anemia-homozygous recessive disorder of the protien in hemoglobin so hemoglobin carries less O2 and causes RBC to become sickle shaped


Huntingtons chorea-protein disorder that causes motor movement problems, dominant protein disorder

Prion disease

misshapen proteins that cause normal proteins to become misshapen. proteins can not function normally.

examples of prion diseases

Bovine Spongioform Encephalopathy (BSE)=mad cow disease


Scarpie=prion disease in sheep


Chronic Wasting Disease (CWD)=prion disease in deer


Variant Creutzfeld Jakob Disease (vCJD)=in humans, brain shrivels

Monosaccharides

single sugar unit


-glucose


-galactose


-fructose

Disaccharides

2 sugar units


-sucrose


-lactose


-maltose

Polysaccharides

more than 2 sugars


-starch


-cellulose


-glycogen

fats

triglycerides and fatty acids

phospholipids

membrane

ketosis

use of ketones for energy

ketoacidosis

a drop in blood pH from metabolizing ketones

prostaglandins

lipid based hormone.


inflammation


menstral cramps

steroids

hormones, lipid based

exogenous steroid

steroid outside body



anabolic steroid

synthetic tesosterone

birth control hormones

estrogen and progesterone

anti inflammatory steroids

corticosteroids and hydrocortizone


prednisone and prednisolone

endogenous steroid

steroid that body produces naturally


cholesterol


=cortisol, testosterone, estrogene, progesteron

insulin

blood glucose too high


take up blood glucose


decrease blood glucose

glucagon

blood glucose too low


tells liver to break down glycogen to glucose so that it is released into the blood stream

nursing

1. baby sucking on nipple


2. tactile receptors


3. hypothalamus


4. supraoptic and parventricular nucleus


5. milk release from breast

birthing

1. baby stretching cervix


2. stretch receptors in cervix


3. hypothalamus


4. supraoptic and paraventricular nucleus


5. strong uterin muscle contraction

body temperature

1. body temp goes down or up


2. thermoreceptors


3. anterior hypothalamus


4. too high, sweat glands; too low, skeletal muscle


5. return to normal body temp

regulation of blood glucose

1. blood glucose outside normal range


2. pancreas


3. blood glucose remains stable

blood pressure

1. bp is out of normal range


2. arteries closest to heart aortic and carotid arteries baroreceptors


3. medulla oblongata


4. heart


5. increased or decreased heart rate

carbohydrates

monosaccharides


disaccharides


polysaccharides

lipids

fats


phospholipids


ketones


prostaglandins


steroids

proteins

enzymes


hemoglobin


insulin and glucagon


antibodies


acid phosphate


creatine phosphokinase



cystic fibrosis

chronic mucous in the lungs due to a homozygous recessive disorder fo a protein on alveolar cells

sickle cell anemia

homozygous recessive disorder of the protein in hemoglobin

Huntington's chorea

protein disorder that causes motor movement problems

prion disease

misshappen proteins that cause normal proteins to become mishappen proteins cant function normall

bovine spongioform encephalopathy

mad cow disease

scrapie

prion disease in sheep

chronic wasting disease

prion disease in deer