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9 Cards in this Set
- Front
- Back
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Leukemia
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Malignant proliferation of blood forming cells usually accompanied by large numbers of cells in the peripheral blood
Can be lymphocytic, myelocytic, erythrolekemia, monocytic leukemia, megakaryocytic leukimia |
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two major classes of leukemia
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Acute-ALL, AML
Chronic-CLL, CML |
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Most common leukemia in children under age 15
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ALL
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Most common leukemia in adults
Dramitic increase after age 40 Most prevalent in 6th, 7th, 8th decades |
AML
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2nd most common leukemia in adults
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CLL
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Things implicated in leukemia
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-Long term exposure to chemicals
-chromosomal translocations and oncogenes -prolonged exposure to radiation -enviromental angents -previous chemotherapy -infection with HTLV-1, HBV, KSHV/HSV-8 -Other diseases with chromosomal abnormalities |
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Sypmtoms common to all types of Leukemia
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-Unexplained fevers
-Frequent infections -Night sweats -fatigue -weight loss -easy bruising |
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Other symptoms associated with leukemia (vague)
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headache, confusion, ataxia, blurred vision, Lymphadenopathy, SOB, n/v, splenomegaly, hepatomegaly, pain in the bones/joints, muscle weakness, seizures
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Classification of leukemias
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By the FAB group in 1976
Based on morphological criteria |
