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9 Cards in this Set

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  • Back
Malignant proliferation of blood forming cells usually accompanied by large numbers of cells in the peripheral blood

Can be lymphocytic, myelocytic, erythrolekemia, monocytic leukemia, megakaryocytic leukimia
two major classes of leukemia
Acute-ALL, AML
Chronic-CLL, CML
Most common leukemia in children under age 15
Most common leukemia in adults

Dramitic increase after age 40
Most prevalent in 6th, 7th, 8th decades
2nd most common leukemia in adults
Things implicated in leukemia
-Long term exposure to chemicals
-chromosomal translocations and oncogenes
-prolonged exposure to radiation
-enviromental angents
-previous chemotherapy
-infection with HTLV-1, HBV, KSHV/HSV-8
-Other diseases with chromosomal abnormalities
Sypmtoms common to all types of Leukemia
-Unexplained fevers
-Frequent infections
-Night sweats
-weight loss
-easy bruising
Other symptoms associated with leukemia (vague)
headache, confusion, ataxia, blurred vision, Lymphadenopathy, SOB, n/v, splenomegaly, hepatomegaly, pain in the bones/joints, muscle weakness, seizures
Classification of leukemias
By the FAB group in 1976

Based on morphological criteria