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55 Cards in this Set

  • Front
  • Back
acetominaphin
MOA- mechanism of analgesia unknown. Antipyretic action is due to central (hypothalamic) inhibition of endogenous pyrogens

PTU- antipyretic, analgesic
albuterol
MOA- selective beta-2 receptor agonist

PTU- bronchodilator
alendronate
MOA- bisphosphonate; inhibitor of osteoclast mediated bone resporption

PTU- osteoporosis
amlodipine
MOA- dihydropyridine calcium channel antagonist

PTU- hypertension, angina
amoxyicillin
MOA- antibiotic; bacterial cell wall synthesis inhibitor

PTU- UTI, upper respiratory infections including otitis media and sinusitis
amoxicillin with clavulanate
MOA- antibiotic; bacterial cell wall synthesis inhibitor with beta lactamase inhibitor

PTU- same as amox plus adds extended coverage to also be useful for diabetic foot ulcer and community acquired pneumonia
aspirin
MOA- acetylates platelet cyclooxygenase. inhibits prostaglandin synthesis.

PTU- antiplatelet (post MI), antiinflammatory, antipyretic, analgesic
atorvastatin
MOA- hydroxymethyl glutaryl coenzyme A (HMGCoA) reductase inhibitor--blocks endogenous cholesterol synthesis

PTU- hypercholesterolemia, mixed hyperlipidemia (both cholesterol and triglyceride elevation)
azythromycin
macrolide antibiotic that binds to the 50S ribosomal subunits of bacteria and supress protein synthesis

PTU- upper and lower respiratory tract infections including sinusitis, community acquired pneumonia, acute exacerbation of chronic bronchitis and includes coverage of some atypical organisms such as chlamydia, legionella, and mycoplasma.
Bupropion
MOA- norepinephrine and dopamine reuptake inhibitor

PTU- antidepressant, smoking cessation.
candesartan
MOA- angiotensin receptor blocker

PTU- hypertension, chonic heart failulre, left ventricular dysfuction
celecoxib
MOA- selective cyclooxygenase 2 inhibitor, inhibits prostaglandin production

PTU- analgesic, antiinflammatory
cephalexin
MOA- bacterial cell wall synthesis inhibitor (first generation cephalosporin)

PTU- skin and soft tissue infections, UTI
cetirizine
MOA- nonsedating, antihistamine

PTU- allergic sinusitis/ rhinitis
ciprofloxacin
MOA- interfere with DNA gyrase, an enzyme necessary for the synthasis of bacterial DNA

PTU- UTI, systemic infections where gram negative organism suspected, gonorrhea
clopidogrel
MOA- selective and irreversible inhibitor of platelet activation by binding to the ADP dependent receptor on platelets

PTU- antiplatelet
Diazepam
MOA- benzodiazepine receptor agonist

PTU- muscle relaxant, anxlolytic, anticonvulsant, alcohol withdrawl
Diltiazem
MOA- calcium channel blocker

PTU- hypertension, angina, slow heart rate in supraventricular tacharrhythmias
Doxazosin
MOA- alpha-1 receptor antagonist

PTU- hypertension, prostatic hypertrophy
Erythromycin
MOA- macrolide antibiotic that binds to the 50S ribosomal subunits of bacteria and suppress protein synthesis

PTU- alternative when pt allergic to penicillin; upper and lower respiratory infections, skin and soft tissue infections, chlamydia, legionella, and mycoplasma
Fluticasone
MOA- inhibits phospholipase A2 and other multiple antiinflammatory actions

PTU- inhaled antiinflammatory agent for treatment of persistant asthma; nasal for allergic rhinitis
fosinopril
MOA- angiotensin converting enzyme (ACE) inhibitor

PTU- hypertension, congestive heart failure
Furosemide
MOA- block sodium reabsorption from ascending limb of loop of henle

PTU- loop diurectic
Gemfibrozil
MOA- increases lipoprotein lipase activity and decreases VLDL synthesis in the liver

PTU- hypertriglyceridemia
Glyburide
MOA- Sulfonylurea antidiabetic agent that increases insulin secretion from the pancreas

PTU- diabetes mellitus (DM) type 2
hydrochlorothiazide
MOA- blocks sodium reabsorption from the proximal portion of the DCT

PTU- (thiazide) diuretic, hypertension
ibuprofen
MOA- inhibits cylcooxygenase, inhibits prostaglandin production

PTU- antiinflammatory, analgesic, antipyretic
insulin
MOA- binds to endogenous insulin receptor

PTU- DM type 1 or 2
ipratropium bromide
MOA- cholinergic receptor antagonist

PTU- bronchodilator for COPD
Levofloxacin
MOA- quinolone antibiotic; interferes with DNA gyrase, an enzyme necessary for the synthesis of bacterial DNA

PTU- UTI, community acquired pneumonia
lisinopril
MOA- ace-inhibitor

PTU- hypertension, CHF
lorazepam
MOA- bensodiazepine receptor agonist

PTU- anxiolytic, anticonvulsant, antiemetic (combined with other agents), alcohol withdrawl
Losartan
MOA- angiotensin II receptor antagonist

PTU- hypertension and nephropathy in DM type 2
metformin
MOA- biguanide antidiabetic; decreases hepatic glucose production and increases insulin sensitivity

PTU- DM type 2
metoprolol
MOA- selective B-1 receptor antagonist

PTU- hypertension, angina, heart failure, post MI
Montelukast
MOA- leukotriene receptor antagonist

PTU- mild persistant asthma
Morphine
MOA- opiate agonist

PTU- analgesic
Naproxen
MOA- inhibits cyclooxygenase; inhibits prostaglandin production

PTU- antiiflammatory, analgesic, antipyretic
Nifedipine
MOA- calcium channel antagonist

PTU- Hypertension
omeprazole
MOA- H-K ATPase enzyme inhibitor; blocks gastric acid secretion

PTU- duodenal ulcer, gastric ulcer, GERD
oxycodone (alone or with acetaminophen)
MOA- opiate agonist

PTU- analgesic
Paroxetine
MOA- selective serotonin reuptake inhibitor

PTU- depression, social anxiety disorder, generalized anxiety disorder, panic disorder
penicillin VK
MOA-Bacterial cell wall synthesis inhibitor (penicillin antibiotic)

PTU- upper and lower resp infections
Phenytoin
MOA- Na channel blocker

PTU- anticonvulsant
Prednisone
MOA- inhibits phospholipase A2 and other multiple antiinflammatory actions

PTU- oral antiinflammatory agent for treatment of multiple inflammatory conditions
Propranolol
MOA- non selective B-1 and B-1 receptor antagonist

PTU- hypertension, angina, slow heart rate, and migraine
Ranitidine
MOA- Histamine-2 receptor blocker; reduce gastric acidity

PTU- duodenal ulcer, gastric ulcer, GERD
Rosiglitazone
MOA- insulin sensitizer; improves insulin action in the presence of insulin

PTU- DM type 2
Salmeterol
MOA- long active selective B-2 receptor agonist

PTU- bronchodilator
sertraline
MOA- serotonin selective reuptake inhibitor

PTU- depression, OCD, panic attacks
Sildenafil
MOA- selective inhibitor of cyclic guanosine monophosphate (cGMP) phosphodiesterase type 5 (PDE)

PTU- erectile dysfunction
Simvastatin
MOA- HMGCoa reductase inhibitor

PTU- hypercholesterolemia, mixed hyperlipidemia (both cholesterol and triglyceride elevation)
Trimethoprim/ sulfamethoxazole
MOA- antibiotic; sequential antimetabolite

PTU- UTI, upper repspiratory infections, pneumocystis carinii pneumonia
Verapamil
MOA- calcium channel antagonist

PTU- hypertension, angina, to slow heart rate, supraventricular tachyarrhythmias
warfarin
MOA- vitamin K antagonist

PTU- anticoagulation