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89 Cards in this Set
- Front
- Back
describe what a parasite does
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thrives at the expense of others
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single celled eukaryotes are called?
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protozoa
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multicellular eukaryotes are called?
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metazoa...
including: helminths(worms) arthropods mollosucs |
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arthropods and molloscks act as ____ and reservoirs for both protozoan and helminth parasites
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vectors
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protozoa: describe the function of:
inner and outer endoplasm |
inner: nutrition
outer: locomotion |
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entameba coli cyst and entameba coli trophozite: do they look the same?
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no
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classification of protozoa: is on the basis of?
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reproduction and locomotion
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define:
organs of locomotion and reproduction for: rhizopods |
locomotion: pseudopods
reproduction: binary fission |
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define:
organs of locomotion and reproduction for: ciliates |
locomotion: cilia
reproduction: binary fission |
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define:
organs of locomotion and reproduction for: flagellates |
locomotion: flagella
reproduction: binary fission |
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define:
organs of locomotion and reproduction for: sporozoa |
locomotion: none
reproduction: schizogony (multiple fission) |
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name 2 rhizopods
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entamoba histolytica
acabthamoeba spp |
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name a ciliate
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balantidium coli
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name 2 flagellates
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giardia lamblia
trichomonas vaginallis |
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name 2 sporozoa
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plasmodium spp ( malaria)
toxoplasma gondii |
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who am i:
ventral suckers, multiple flagella, no 1 water parasite that causes GI toxicity |
giardia lamblia
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what is a kinetoplastid?
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refers to an order of flagellate protozoa with special characteristics
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describe a kinetoplastid?
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one mitochondria
one/two flagella comin out |
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list 3 kinetoplastids
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t. cruzi
t. brucei- leishmania spp ( leischmaniasis) |
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T. CRUZI IS?
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a kinetoplasmid
-- chagas disease, latino, cardiomyopathy |
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t. brucei is?
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a kinetoplastid
sleeping sickness, in the brain african |
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leishmanisis is?
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affects the visceral, skin
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protozoan asexual reproduction:
flagellates divide bY? ciliates divide by? |
flagellates divide by longitudinal fission
ciliates divide by transverse fission |
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sexual reproduction of protozoan parasite:
exampleL CRYTOSPORIDIUM PARVUM -->Intestine? -->thick walled? |
intestine: both sexual and asexual
thick walled: continues sexual "oocyst" |
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classification of helminths:
based on? 4 factors |
1. morphology
2. sex 3. alimentary tract 4. no of intermediate hosts |
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roundworm:
define the morphology, sex, alimentary tract, no of intermediate hosts |
1. morphology: spindle shaped
2. sex: separate 3. alimentary tract: tubular 4. no of intermediate hosts: varies |
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cestode/tapeworm:
define the morphology, sex, alimentary tract, no of intermediate hosts |
1. morphology: head with segmented body
2. sex: hermaphordite 3. alimentary tract: none 4. no of intermediate hosts: one |
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fluke ( trematode)
define the morphology, sex, alimentary tract, no of intermediate hosts |
1. morphology: leaf shaped with oral and ventral suckers
2. sex: hermaphordite 3. alimentary tract: blind 4. no of intermediate hosts: two |
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schistosoma group ( fluke):
define the morphology, sex, alimentary tract, no of intermediate hosts |
1. morphology: head with segmented body
2. sex: SEPARATE 3. alimentary tract: none 4. no of intermediate hosts: one |
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diphyllobothrium(roundworm):
define the morphology, sex, alimentary tract, no of intermediate hosts |
1. morphology: spindle shaped
2. sex: separate 3. alimentary tract: tubular 4. no of intermediate hosts: two |
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name all the nematodes (roundworms):
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pin
round woucherarria spp loa loa |
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name all the cestodes (tapeworm)
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pork
tapeworm segments scolex e. granulosus |
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name all the trematodes ( flukes)
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schistosoma
liver fluke |
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vectors:
mosquito ___ tsetse fly____ |
mosquito: malaria
tsetse fly: trypanosomiasis |
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vectors:
riduviid bug:___ phlebotomous sandfly:___ |
riduviid bug: chagas disease
phlebotomous sandfly: leischmaniasis |
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vectors:
crysops fly:__ tick:__ |
crysops: loa loa--> eye worm
tick: babesiosis ( lyme disease) |
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what are myiasis?
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flies that lay their larvae in wounds
ex: dermtobia hominis ( BOT fly) warble flies, house flies --all transport diseases |
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characteristics of a definitive host?
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1. parasite passes its adult phase (metazoa) or its sexual reproductive phase ( protozoa)
ex: t. vaginalis ( active trophozites transmitted by direct genital contact or sex). Also: Gardi ( flagellate) |
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characteristics of an intermediate host
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1. paraste passes through its larval ( metazoa) or asexual
(protozoa) phase of its life **primary and secondary hosts exist. Plasmodium ( malaria): transmitted from human to human via mosquito ( intermediate host) . humans are the definite hosts. |
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advantage of definitive host
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sexual recombination and diversity
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advantage of intermediate host
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higher levels of the parasite in the population
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Taxoplasma remains in a dormant state in the absence of an appropriate host. what form?
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cyst forms ( kitty litter)
--via carnivorous behavior |
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parasites usually infect chronically or acutely?
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chronically, since an acute infection can trigger an immune attack ( chronic and long term)
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what is the form of dissemination of a pig hookworm and nematods?
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larvae: hook worm ( cyst)
nematodes: eggs |
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taenia solium: who is the intermediate host? definitive host?
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intermediate: pigs
definitive: humans |
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parasite usually:
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1. long term residence
2. chronic infection 3. resides in a metabolically inactive form 4. no global response to immune system ( to avoid killing host) 5. parasite load < host load 6. does not affect fitness of the host 7. must ensure trasmission to the new host |
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stages of the parasitic infection:
1. what are they? |
1.incubation period
2. prepatent period 3. patent period |
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stages of the parasitic infection:
define incubative |
time that u acquired the infection to the time the symptoms manifested ( hours to years)
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stages of the parasitic infection:
prepatent? |
time between infection with a parasite and demon. of the parasite in the body ( oocyts or eggs ) from blood/feces.
--CAN BE SHORTER THAN INCUBATORY PERIOD (infection can be detected before symptoms show up) -days to years |
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stages of the parasitic infection:
patent period |
- course of a parasitic disease during which parasitic organisms can be demonstrated in the body
- no symptoms needed -days to years |
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what is the highest incidence of parasitic diseases in US?
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Enterobius vermicularis (pinworm-- 50 million)
---intestinal roundworms are 1.4 billion |
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the biggest killer?
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malaria
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identification of parasite:
1. stool? |
ova of worms
cysts of protozoa |
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identification of parasite:
2. urine |
schistosoma haematobum (africa)
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identification of parasite:
3. blood |
plasmodium
leischmania trypansomes |
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identification of parasite:
4. tissue |
skin and muscle:
onchocerca trinchinella (large bowel infection: histolytica and S. mansoni) |
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why is diagnosis of parasitic infection difficult?
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less characteristic clinical manifestation
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serologic exams:
serum? ABS |
toxoplasmosis
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serologic exams: Ag
1. blood 2.tissue 3.excreta 4. body fluids |
1. blood: plasmodium
2. body fluids: carni and t vaginalis 3. tissues: gondii 4. excreta: histolytica, giardia ad cryptosporidium |
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name 4 parasites that DNA probes can be used to identify
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1. p. falciparum
2. t. cruzi 3. t. brucei 4. oncocerca spp ( and agents of lymphatic filariasis) |
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what 3 things does a naked virus have?
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genome
protein core (nucleocapsid- direct contact with genome) capsid, outer shell **no lipid bilayer |
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what 5 things does an enveloped virus have?
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genome
nucleocapsid matrix proteins envelope: lipid bilayer membrane glycoproteins |
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how are envelopes of an enveloped virus obtained?
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via budding from host cells
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where are viral receptors located?
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on a virus, determines host range of virus
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RNA genome of influenza is/isnt segmented?
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segmented
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retroviruses carry how many copies of the genome?
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2
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parvoviruses are?
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non segmented
single stranded DNA molecules very small |
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reoviruses are?
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segmented
double stranded RNA |
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can a capsid or envelope glycoprotein be used to identify the serotype of a virus?
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yes
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what is a virus isolate?
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virus cultured from an individual that is unique and distinct in sequence from other related viruses
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RNA virus:
double/single stranded? envelope? |
dsRNA genome
naked |
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calicivirdae
rna/dna? +/-? envelope? |
+
ssRNA naked like picornaviridiea |
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picornaviridae
+/-? envelope? RNA/DNA? |
+ssRNA
no envelope like calicivirdae |
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flavviridae
+/- ssRNA genome? enveloped? |
+ssRNA genome
enveloped "it has flavor" |
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togaviridae
+/- ssRNA genome? enveloped? |
+ssRNA genome
enveloped just like flavivirdae |
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retrovirsus
+/- ssRNA genome enveloped ? |
diploid
yes envelope +ssRNA |
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retrovirsus
coronaviridae +/- ssRNA genome enveloped ? |
envelope
+ssRNA like flaviv + togaviridae |
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Rhabdoviridae:
+/- ssRNA genome envelope/no envelope? |
- ssRNA
envelope |
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bunyaviridae
+/- ssRNA genome envelope/no envelope? |
-ssRNA
3 circular segments enveloped (zoonotic) |
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orthomoyxoviridae
+/- ssRNA genome envelope/no envelope? |
enveloped
- ssRNA 8 SEGMENTS |
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paramyxoviridae
+/- ssRNA genome envelope/no envelope? |
- ssRNA
enveloped |
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Arenaviridae
+/- ssRNA genome envelope/no envelope? |
- ssRNA
-2 segments enveloped |
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name all the dna viruses
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papovirus,
adenovirus, hepavirus herpesvirus poxvirus |
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which DNA virus contains equal amounts of sense and antisense ssDNA? is it enveloped?
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parvovirus,
naked |
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does papovavirus have an envelope? is it circular or linear double stranded DNA genome
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circular
no envelope double stranded |
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adenovirus:
linear? enveloped? |
naked
double stranded DNA |
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hepadnaviridae
what kind of genome? enveloped? special?? |
dsDNA
enveloped gapped |
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herpes virus:
genome? enveloped? |
dsDNA genome
enveloped |
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poxvirus
genome? enveloped? |
dsDNA
DUAL ENVELOPED!! |