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33 Cards in this Set

  • Front
  • Back
What is the study of how disease is distributed in populations and the factors that influence or determine this distribution?
Epidemiology
How is epidemiology applied?
To improve health in populations and for specific patients
What composes clinical epidemiological research?
the what, who, when where and why
What composes the biomedical epidemiological research?
the how?
List the three general aspects of the study of epidemiology
Population
Disease
Application
What is distribution?
Who in the population is affected?
What are determinants?
What factors contribute to disease?
What is the prognosis?
How does the disease progress? what is the typical outcome?
This type of epidemiology studies entire community populations and focuses on risk factors that might be altered in the general population to prevent or delay disease, injury or death
Classical epidemiology
This type of epidemiology studies patients in health care settings (people who are ill) and focuses on factors related to disease management
Clinical epidemiology
Why would you use population data in clinical medicine?
To gain a better understanding of health and disease and to apply populations-based data to the care of individual patients
What's the importance of defining the population under study?
Important bc certain diseases affect certain people differently. Can characterize by race, age, gender, location, etc.
How is population data applied to the practice of clinical medicine?
The differential diagnosis is based upon understanding of how disease generally presents in similar people
What are the general aspects of disease?
-Defining features of the disease
-Risks for developing disease
-Etiology of disease (underlying cause)
-Process and Outcome of disease
BEINGS Model
Biologic & Behavioral factors
Environmental factors
Immunological factors
Nutritional factors
Genetic factors
Services; Social & Spiritual factors
Central Dogma of Health & Disease
There is a threshold of risks (stressors that challenge homeostasis); once the threshold is reached the disease process is detectable in patients; the process of disease is pathogenesis, pathophysiology and prognosis
What do epidemiological studies focus on?
Epidemiological studies focus on identifying general causes and do not aim to determine the underlying biological mechanisms of disease
What is the epidemiologic triad?
Agent (Plasmodium), Host (Human), Environment (Mosquitos/Water/Infected people); sometimes includes a vector (Anopheles mosquito);
What are the components of the epidemiologic triad?
Host factors
Agents of disease
Environment
Vectors
Define host factors:
Degree to which individuals adapt to stressors produced by the agent
What are some agents of disease?
Biologic, chemical, physical, social/psych
What is the environment?
Probability and circumstances of exposure of host to agent
What are vectors?
Insects, arthropods, animals; must have a specific relationship with agent, host, and environment
What are the four goals of epidemiology?
1) Identify the extent of disease in population
2) Identify risk factors/ etiology
3) Study disease progression and prognosis
4) Evaluate existing approaches to prevention and intervention
T/F: Clinical epidemiology often focuses on characterizing responses to disease intervention (prevention; treatment)
True
What is an epidemic?
The unusual occurrence of disease
What is an endemic?
Disease occurs within a population at a relatively constant level
Attack rate equation
# new cases
__________________ X 100
# persons exposed
What is the general outline for investigating an epidemic?
Why did this person become sick with this disease at this time and this place?
preventing the emergence or development of risk factors before they have a chance to appear
Primordial prevention
the risk factors are present, but action is taken prior to the emergence of disease such that the possibility of disease occurring is removed
Primary prevention
disease is present, but actions are taken to halt the progression of disease at its earliest phases such that complications are averted
Secondary prevention
the disease has progressed; interventions focus on “all the measures available to reduce or limit impairments and disabilities, and to promote the patients’ adjustment to irremediable conditions
Tertiary prevention