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19 Cards in this Set
- Front
- Back
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Define poison
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SYMPTOMS result from EXPOSURE
--> depends on the INTENSITY and LENGTH OF TIME |
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What are children of <6 exposed to? (8)
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1. cosmetics/personal care
2. analgesics 3. household cleaning substance 4. foreign bodies 5. Topicals 6. Cough and cold 7. Vitamins 8. Antihistamines |
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What are adults > 20yoa exposed to? (7)
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#1. Analgesics
2. Sedatives/antipsychotics 3. cleaning substances 4. antidepressants 5. CV drugs 6. Alcohols 7. bites/envenomations |
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What is the route of exposure?
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77% ingestion
8% dermal; esp. organic phosphates |
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Why do ppl get exposed? children? adult? teens?
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children (99% unintentional)
adults (64% unintentional--therapeutic error (39%) teens (13-19) 49% intentional |
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Therapeutic errors in children
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1. med given twice
2. wrong dose 3. Confused units measure 4. wrong med |
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Therapeutic errors in adults
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1. med given twice
2. wrong med 3. wrong dose 4. took someone's med (UNIQUE TO ADULT) |
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What is the outcome??
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OUTCOMES IN CHILDREN IS MUCH BETTER
(91% NO EFFECT VS. 61% IN ADULT) |
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What poisons kill people?
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CNS DEPRESSANTS!
--TCA IS LIKE A BULLET TO THE HEAD. SSRI INSTEAD! 1. Hypnotics/sedatives/antipsychotics 2. Opioids 3. Antidepressants (TCA, amytriptyline) 4. CV (BB, CCB) 5. APAP combo products (liver tox) |
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Meds that can kill a child with 1 dose
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BBCCTTO
1. Beta blockers 2. Benzocaine 3. CCB 4. Clonidine patch 5. Theophyline 6. Oral hypoglycemics 1 WHOLE CIG OR 3 CIG BUDS |
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Minimally toxic substances
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silica gel
2% hydrogen peroxide glow jewelry flouride toothpaste laundry bleach |
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poison tx decontamination --> REMOVE THE POISON FROM THE PT! 44% DECON ONLY.
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#1. dilution/irrigation
2. food/snack 3. activated charcoal 4. fresh air other antiemetics, gastric lavage, whole bowel irrigation, HEMODIALYSIS (MOST INVASIVE) |
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What makes a drug dialyzable?
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MW, protein binding, Vd, RBC binding, Elimination, BA, Plasma CL, H2O solubility
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BENZO Overdose?
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NEVER GIVE FLUMAZENIL unless in outpt surgery
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poison tx "antidotes"
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Oxygen
N-acetylcysteine (APAP) Benzos - for pt who are agitated, hallucinative, can use for almost anything. Anticholinergic! Naloxone, ventilator --> opiod OD Calcium --> CCB Bronchodilators --> environmental poison Flumazenil --> Outpt surgery only!! (benzo) |
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Drinking air conditioner coil cleaner, containing hydrofluoric acid and HCL?
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surface burn and deep tissue scars
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a 14 month old boy ingested a mouthful of lamp oil...
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lungs - chemical pneumonitis
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A teacher observed two 13 yo boys spraying an aerosol air freshener into a sock...
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Lethal cardiac arrythmia --> sentitize myocardium to catecholamine.
INHALANTS CAN KILL YOU THE 1ST TIME. |
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AGE >10 YO ingesting bleach?
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psychiatric emergency!
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