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8 Cards in this Set
- Front
- Back
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governing body that regulates the development of the sale of drugs |
the food and drug administration |
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pregnancy categories. A, B, C, D, X |
A- no risk in controlled human studies B- no risk in other studies C- Risk not ruled out D- Positive evidence of risk X- contraindicated in pregnancy: studies show abnormalities and or positive risk of fetal risk |
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what are receptor sites |
a point or structure in a cell at which comnination with a drug or other agents result in a specific change in cell function. |
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blood brain barrier
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a filtering mechanism of the capillaries that carry blood to the brain and spinal cord tissue, blocking the passage of certain substances.
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What is the relationship between plasma protein binding and drug half life?
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drug's efficiency may be affected by the degree to which it binds to the proteins within blood plasma. The less bound a drug is, the more efficiently it can traverse cell membranes or diffuse
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Antagonist
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A substance that acts against and blocks an action. Antagonist is the opposite of agonist. Antagonists and agonists are key players in the chemistry of the human body and in pharmacology.
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1. Full agonists
2. Partial agonists |
1. are opioid drugs that bind to mu opioid receptors in the brain, and cause them to produce endorphins which give analgesic (pain relief) and, depending on the dose and frequency, addictive effects and feelings of euphoria 2. are drugs that bind primarily to mu opioid receptors and cause them to produce endorphins but to a much lesser extent than full agonists. Buprenorphine®, Suboxone® and Subutex® are partial agonists. |
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6 rights of drug administration
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Right drug, right person, right dose, right time, right route, right documentation
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