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15 Cards in this Set
- Front
- Back
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1.What are the general characteristics of fungi as organisms?
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ggg
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1. General characteristics of fungi as organisms
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1. eukarotic, multicellular (mostely)
2. ergosterol (instead of cholesterol) in membrane 3. cell wall and components* 4. metabolism is heterotrophic 5. aerobic 6. reproduce asexually/sexually-only see ASEXUALLY CLINICALLY 7. are NOT in plant kingdom 8. SAPROPHTYIC-soil dwellers, can live on dead orgnaic material 9.suspectible to our non sepcifc and specific defenses |
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2. factors involved in fungal pathogenesis
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1. they like acidic pH
2. adherence 3. invasion 4. resistance 5. tissue injury 6. allergic rxn |
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Cell walls components:
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1. peptidomannan
2. glucan 3. chitin 4. cellulose 5. chitosan |
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How many fungi cause disease in man? how mnay of those are common?
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175; 30 are common
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know slide 3 -chart of prokaryoties vs. eukarytes
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slide 3
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All fungi can act as what? meaning they don't require growth?
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as allergens; fungi that cause disease have adapted or are opportunitsts.
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how do you classify fungi?
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on the type of sexaul spores and SEPTATION of hyphal mycelia
1. septate 2. non-septate(coenocytic)-no cross wall |
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Basic methods of fungal identification
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a. suspect: bacteria>virus>fungi
b. scape>digest w/KOH to digest tissue & view: i.only need to confirm that uts fungal: see micilia, sproes, yeast phase ii. treat w/antifungals (broad spectrum) |
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the clinical classification of medically relevant fungi:
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a. superficial
b. cutaneious>keratinolgytic c. subcut>requires implantation, rare d. systemic>larege expsoure,: inhalation>problematic in immunodeficient 3. opportunitstisc>imparied host defense: alteration in normal flora |
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Growth and morphology of fungi: yeasts vs. molds
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Yeasts: unicellular, circular, repoduce by budding, resemble bacteria colonies
Molds: multicelluar; grow as hypaae(sextension of cell wall): either a. multiple hypahe>mycelia b. vegatitive hypahe?roots; spores here |
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Dimorphism:
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ability to grow either asa yeast (37C) or mold (25C); most fungi--Aspergillas; allows for pathogeneisis
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lab growth and diagnoiss:
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1. use Sabourad's agar-sliightly acidic media that bacteria or other growth
2. state of septation & type of ascual sproes produced in mold sate 3. cab assimilationtests 4. Dual culutre at the two different temps 5. ant/ab detection, n.acid hypridcation (PCR) |
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asexual reproudction of fungi
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via mitosis: as in budding (yeast)
1. single cell reoval and regneration (arthrocodidida) 2. generation of spores, aka condidia 3. sproe morphology the major means of funal identification** |
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Sexual reproduction
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azygospores, ascospores, basdidiospres; cell fusion (mating) dipolidy, differention, meoisis, deipoloid or hapolid spores
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