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86 Cards in this Set

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Integumentary system consists of 6 items

Skin


Hair


Nails


Sensory receptors


Exocrine glands


Dermal blood vessels

The average adult has how much skin?

Surface area of 1.2 sq meters (4 sq feet) & 2.2 sq meters 7 sq feet


Skin weighs about 4-5kg 10lb or 7% of body weight


Thickness 1.5-4.0 mm

Skin has 2 regions

Top epidermis


Bottom dermis

Epidermis is made of

Stratified kerantized squamous epithelium. It is avascular, it's thickness is between .01 &1.0mm

What are the 4 cells found in the epidermis?

Keratinocytes


Melanocytes


Merkel cells


Langerhans cells

Keratinocytes

Are most abundant, make a protein called keratin. Keratin is waxy & waterproof. It gives the epidermis it's protective properties

What is the deepest layer of the epidermis?

Stratum basale.

What is the deepest layer of the epidermis?

Stratum basale.

Keratinocytes undergo mitosis in

The stratum basale

The superficial layer of the epidermis is the

Stratum corneum

Keratinocytes die on their journey from the stratum basale to the stratum corneum. The journey takes between

25-45 days. The stratum corneum is composed of dead keratinocytes.

Dead keratinocytes have thickened plasma membranes are filled with keratin

Every month or so we acquire a completely new epidermis.

A callus is the result of

Persistent friction which causes accelerated keratinocyte production

Melanocytes make a dark pigment called melanin

Keratinocytes pick up melanin & use it to shield their nuclei from UV radiation I.e. Suntan

Langerhans cells

Arise in bone marrows& migrate to the epidermis


Are phagocytes & ingest foreign substances that penetrate the epithelium, they take it to the lymph nodes to help activate the immune system.

Merkel cells AKA Merkel disc

Encapsulated nerve ending found in the epidermis. Merkel disc consists of a Merkel cell that surrounds the end of a sensory neuron. Light touch is sufficient to deform the Merkel disc. When disc is deformed it causes the sensory neuron to generate and conduct a nerve impulse

What are the 5 layers of the epidermis?

Stratum basale"basement"


Strtum spinosum


Stratum granulosum


Stratum lucidum


Stratum corneum "outer most"

Stratum basale consists of

A single layer of cells which under go continuous mitosis.mitosis gives rise to the youngest keratinocytes which replaces worn off cells

Stra

Stratum corneum

Is the superficial layer of the epidermis, it is about 20-30 cell layers thick.accounts for 75% thickness of the entire epidermis . Is composed of dead keratinocytes.

What are the 2 layers of the dermis?

Superficial layer--Papillary layer


Deep layer--reticular layer


The papillary layer iS made of what tissue?

Loose Areolar connective tissue.


The papillary layer iS made of what tissue?

Loose Areolar connective tissue.

What percentage of dermal thickness does the papillary layer form?

20% it is nipple like

The papillary layer is highly vascular. Vessels in the dermis

nourish the cells avAscular epidermis

Name the 3 cells found in the papillary layer

Fibroblasts


Mast cells


WBC white blood cells

Dense fibrous irregular connective tissue makes up the

Reticular layer

Reticular layer forms what percentage of dermal thickness

80%

The reticular layer is highly

Vascular

What are the main cells found in the reticular layer of the dermis?

Fibroblasts

Hair follicles are located in the deep _________ layer of the dermis

Reticular

Hair follicles are located in the deep _________ layer of the dermis

Reticular

What is at the base of each hIr follicle?

A hAir root

Hair follicles are located in the deep _________ layer of the dermis

Reticular

What is at the base of each hIr follicle?

A hAir root

A hair root is composed of cells that undergo continual

Mitosis

Hair follicles are located in the deep _________ layer of the dermis

Reticular

What is at the base of each hIr follicle?

A hAir root

A hair root is composed of cells that undergo continual

Mitosis


New keratinozed hair cell acquire color from melanin they die and are fused into

A hAir shaft. Hair grows about 8-10mm each month

Arrector pili muscle AKA Pilomotor muscle

Smooth involuntary muscle GOOSEBUMPS when contracted

Arrector pili muscle AKA Pilomotor muscle

Smooth involuntary muscle GOOSEBUMPS when contracted

Hair follicle receptors are sensory nerve endings

When bent it stimulates tag sensory nerve endings warms of light touch or insects on the skin

Nails are scale like modification of

The epidermis. They cover the dorsal surface of distal fingers & toes .

Nail bed is composed of deep layers of the epidermis

Blood vessels in the dermis that give nails their pink color

Lunula is the proximal white crescent portion it covers the

Nail root cells produced become keratinized & fuse into the nail. The body of the nail the slides distal over the nail bed



Nails about 3mm each month

Nail bed is composed of deep layers of the epidermis

Blood vessels in the dermis that give nails their pink color

Lunula is the proximal white crescent portion it covers the

Nail root cells produced become keratinized & fuse into the nail. The body of the nail the slides distal over the nail bed



Nails about 3mm each month

Cutaneous senses aka general senses these includ

Touch


Pain


Heat


Cold


Pressure

Merkel discs & free nerve endings are sensory receptors housed in the epidermis

Merkel discs are encapsulated nerve endings sensitive to light touch



Free nerve endings un-encapsulated are sensitive to pain heat & cold

Merkel discs & free nerve endings are sensory receptors housed in the epidermis

Merkel discs are encapsulated nerve endings sensitive to light touch



Free nerve endings un-encapsulated are sensitive to pain heat & cold

What are the 4 receptors in the dermis?

Free nerve endings


Meissners corpuscles


Pancinian corpuscles


Hair follicle receptors

Merkel discs & free nerve endings are sensory receptors housed in the epidermis

Merkel discs are encapsulated nerve endings sensitive to light touch



Free nerve endings un-encapsulated are sensitive to pain heat & cold

What are the 4 receptors in the dermis?

Free nerve endings


Meissners corpuscles


Pancinian corpuscles


Hair follicle receptors

Meissners corpuscles

Provide discriminative touch


Know what you are touching

Merkel discs & free nerve endings are sensory receptors housed in the epidermis

Merkel discs are encapsulated nerve endings sensitive to light touch



Free nerve endings un-encapsulated are sensitive to pain heat & cold

What are the 4 receptors in the dermis?

Free nerve endings


Meissners corpuscles


Pancinian corpuscles


Hair follicle receptors

Meissners corpuscles

Provide discriminative touch


Know what you are touching

Pancinian corpuscles are sensitive to

Deeper pressure & bumps

Exocrine glands are formed



from glandular epithelium they are formed by invaginations of the superficial dermis into deeper dermis

What are the 4 exocrine glands of the skin?

Sweat glands aka sudoriferous glands


Oil glands


Ceruminous glands


Mammary glands

Sweat gland facts

The skin had about 3 million sweat glands



Sweat glands are found almost everywhere



There are no sweat glands on nipples & external genitalia

What are the 2 types of sweat glands?

Apocrine & eccrine


Apocrine Located in armpit & genitals

What are the 2 types of sweat glands?

Apocrine & eccrine


Apocrine Located in armpit & genitals

Apocrine sweat gland facts

On average skin has 2k apocrine sweet glands


They are found I. The armpit & genital areas


Inactive until puberty


Not invoked in thermal regulation


Secretions into hair follicles via ductrs


Apocrine secretions is similar to sweat


Contains more proteins and substances


Equate aprocine sweat glands w/sec scent glands in animals

Eccrine sweat glands facts

Found all over the body


Most numerous on pals feet &forehead


Sweat is secreted via a coiled tube located in the dermis


Have ducts that open into pores


Pores are funnel shaped channels


Pores open onto the surface of the skin


Eccrine sweat glands facts

Found all over the body


Most numerous on palms feet &forehead


Sweat is secreted via a coiled tube located in the dermis


Have ducts that open into pores


Pores are funnel shaped channels


Pores open onto the surface of the skin


Cells that line a sweat gland secrete sweat by

Exocytosis

Sweat facts

500 ml on normal day


pH 4- 6


Made from water derived from blood plasma


Contains salts Na sodium & Cl chloride


Contains vitamin C. Anti bodies & trace metabolic wastes

Oil glands )sebaceous glands

Found everywhere but palms & soles of feet


Secrete into hair follicles via ducts


May also secrete directly onto the surface of skin

Sebum is a lipid (oily) substance

Oil glands secrete


Inhibits growth of bacteria


Softens & lubricates skin

Dermal blood vessels

Contains about 5% of the body's blood volume

Dermal blood vessels

Contains about 5% of the body's blood volume

Thermoregulatiom

Smooth muscle in the walls of the arterioles dilate or constrict

Vasodilation

Smooth muscle relaxes arterioles dilate


Increases blood flow through dermal blood vessels


Occurs in a warm environment


Brings excess heat closer to the surface of the skin


Heat in blood is radiated to the envoroment lowering body temp

Vasoconstriction

Smooth muscle contracts


Arterioles constrict


Decreases blood flow through the dermal blood vessels


Occurs in cold environment


Maintains heat within the core of the body

Vasoconstriction

Smooth muscle contracts


Arterioles constrict


Decreases blood flow through the dermal blood vessels


Occurs in cold environment


Maintains heat within the core of the body

Fight or flight is a vasoconstriction of dermal blood vessels blood is sent to

Skeletal muscles heart & brain

Vasoconstriction

Smooth muscle contracts


Arterioles constrict


Decreases blood flow through the dermal blood vessels


Occurs in cold environment


Maintains heat within the core of the body

Fight or flight is a vasoconstriction of dermal blood vessels blood is sent to

Skeletal muscles heart & brain

Vitamin D production begins in

The skin


Modified molecules circulating in dermal blood vessels are converted to a vitamin d precursor when exposed to sunlight


Vitamin d in necessary to absorb calcium from food

Vasoconstriction

Smooth muscle contracts


Arterioles constrict


Decreases blood flow through the dermal blood vessels


Occurs in cold environment


Maintains heat within the core of the body

Fight or flight is a vasoconstriction of dermal blood vessels blood is sent to

Skeletal muscles heart & brain

Vitamin D production begins in

The skin


Modified molecules circulating in dermal blood vessels are converted to a vitamin d precursor when exposed to sunlight


Vitamin d in necessary to absorb calcium from food

Hypodermis AKA superficial fascia

Located deep to the dermis of the skin


Not truly part of the skin


Composed of loose Areolar connective tissue


Maybe composed of adipose connective tissue if fat cells are present.

Hypodermics functions

Absorbs shock


Insulates against heat loss


Defense against infection viaWBC


anchors the dermis loosely to deep fascia

Deep fascia is the dense

Fibrous irregular connective tissue that covers skeletal muscles