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16 Cards in this Set
- Front
- Back
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What 3 things contribute to skin color?
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Melanin, hemoglobin, carotene
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How does hemoglobin (which is inside the red blood cells in dermal BV's) contribute to skin color?
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Upon binding to oxygen, hg exhibits a bright red color giving bv's in the dermis a reddish tint that is seen most easily in the skin of lightly pigmented individuals.
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What determines normal skin color?
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Mostly melanin: gives skin various yellow, reddish, tan, brown, and black shades.
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How is melanin transferred and in what layer does this occur?
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In a membrane-bound vesicle from melanocytes to keratinocytes in the the STRATUM BASALE
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What is the weakest of the skin pigments?
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Carotene. Yellow0orange pigment that is acquired by eating various yellow-orange veggies.
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Where does carotene accumulate?
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Normally inside the keratinocytes of the stratum corneum and within the subcutaneous fat.
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What is significant about carotene in the body?
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It converts to vitamin A!!
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Melanocytes don't work
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Albinism
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"michael jackson" disease loosing patches of melanocytes, it's an autoimmune disease
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vitiligo
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Blueness, lack of oxygen for your hemoglobin, takes on a maroon color, poor oxygenization, caused by malfunction or blockage
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cyanosis and acrocyanosis
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Lack of hemoglobin and red blood cells (anemia), hemoglobin),
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Pallor/paleness
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Yellow-something wrong with liver. Pigment called billyrubin (break-down product of hemoglobin) contributes to bruising
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Jaundice
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Reddish changes, bull's eye rash (lyme disease), skin turns red because vessels dialate which increases redness.
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Erythema
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What is a hematoma
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A bruise (visible pool of clotted blood) is observable through the skin, due to trauma, may be indicative of of hemophilia or a nutritional or metabolic disorder
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What sets in 1-2 hours after death and will initially blanch when squeezed?
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Postmortem lividity (livor mortis)
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What happens to the skin eight hours after death
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Red Blood cells fragment and escape into the surrounding tissues and the area will not blanch when squeezed.
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