Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
38 Cards in this Set
- Front
- Back
|
what tx therapy can increase [p acnes] at high doses?
|
accutane
|
|
|
what is the MOA of propecia?
|
5-alpha reductase-2 inhibitor
|
|
|
what type of drug therapy has both anti-inflamm and immunosupp act?
|
corticosteroids
|
|
|
what is a good/the best prognosis w/ melanoma?
what is a bad/the worst prognosis w/ melanoma? |
1. in ext & infiltration of lymphocytes in tumor
2. vertical growth & inc # of mitotic figures |
|
|
what is dysplastic nevi?
|
abnL growth pattern & cytologic abnL of melanocytes
|
|
|
what is cutaneous histiocytosis X
|
prolif of Langerhan cells in skin & lymph
|
|
|
what is mycosis fungoides?
|
a/w presence of malig T cells in periph blood & erythematous scaling of body surface
|
|
|
what is a xanthoma?
|
a/w aggregates of histiocytes w/ foamy cytoplasm & presence of Touton giant cells
|
|
|
clinical presentation of basal cell carcinoma?
|
- h/o slow growing nodule on upper eyelid
- pearly nodule - nests of small cells w/ radial arrangement at periph --> infilt of epidermis into dermis |
|
|
what type of skin ca responds to imiquimod?
|
superficial type of BCC
|
|
|
what is the most malig type of melanoma?
|
one w/ superficial spreading
|
|
|
when is resection of involved regional lymph nodes required?
|
congenital hairy nevus overlying axillary nodes (brewslow 1.80mm into reticular dermis)
|
|
|
what is telangiectasia?
|
serpiginous, threadlike red lesions w/ blanch on diascopy
|
|
|
clinical presentation of SCC
|
- black pt w/ pigmented streaking on L thumbnail plate
- present for sev mos & growing - asymptomatic and irreg in width |
|
|
what does "B" stand for in melanoma classification - ABCDE?
|
bord3r
|
|
|
solar lentigines
|
- ship captain (sun exposure)
- multiple oval-to-round brown macules on back of forearm & dorsum of hands |
|
|
squamous cell carcinoma clinical presentation
|
- dome shaped, reddish, smooth, firm nodule w/ center crust
- on forehead, slowly enlarging - extensive sun damage around lesion |
|
|
Morpheaform BCC clinical presentation
|
- waxy, white-to-yellow lesion on L cheek x 1 yr
- sclerotic plaque w/ indistinct margins - telangiectasia |
|
|
what is granulation tissue?
|
capillaries & inflamm cells
|
|
|
what is a clean wound?
|
<100,000 organisms/gram of tissue
|
|
|
describe inflamm phase of wound healing
|
no collagen
M-phi & PMNs present |
|
|
how are burns classified?
|
depth of injury
|
|
|
how do partial thickness burn wounds vary?
|
in amt of pain
|
|
|
what are the MC bacT infecting burn wounds?
|
staph
strep |
|
|
what is involved in the initation of tx for burn pts?
|
first stopping burn process
|
|
|
what lifestyle ds inc incidence of wound infection?
|
DM
|
|
|
give an example of a contaminated wound that would require sx
|
colon resection for ruptured diverticulum
|
|
|
when are perioperative abx most effective in preventing infxn?
|
given as close to time of sx as possible
|
|
|
CREST syndrome is best characterized by what?
|
calcinosis
|
|
|
what is an important features of SLE?
|
false + syphilis serology
|
|
|
what is the MC presenting feature in scleroderma?
|
Raynaud's phenomenon
|
|
|
what are glucocorticoids most likely used for?
|
inhibiting formation of prostaglandins
|
|
|
topical glucocorticoids have benificial effect of?
|
atrophy of hypertrophic scars
|
|
|
what are chemical peels used to tx?
|
hyperpigmentation psoriasis
|
|
|
what is sclerotherapy indicated for?
|
varicose & telangietic veins
|
|
|
what is the best topical acne therapy?
|
clindamycin
|
|
|
what is a common and effective keratotic plug
|
alpha-hydroxy acid (fruity acid)
|
|
|
what is PUVA used for?
|
psoriasis
|
