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39 Cards in this Set
- Front
- Back
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Accutane at high doses can
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indirectly increase the concentration of P. acnes
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Propecia finasteride MOA
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inhibits 5-alpha reductase 2 enzyme
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corticosteroids have
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anti-inflammatory and immunosuppressant activities
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Good/best prognosis in melanoma
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melanoma in extremities and infiltration of lymphocytes in the tumor
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bad/worst prognosis in melanoma
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vertical growth phase and increased number of mitotic figures
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dysplastic nevi are characterized by
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abnormal growth pattern and cytologic abnormality of melanocytes
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cutaenous histiocytosis X is
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proliferation of Langerhan cells in skin and lymph node
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mycosis fungoides is
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an association with presence of malignant T cells in peripheral blood and erythematous scaling of body surface
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Xanthoma is associated with
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aggregates of histiocytes with foamy cytoplasm and the presence of Touton giant cells
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Pt presents with h/o slow growing nodule on upper eyelid. Histo exam of pearly nodule shows nests of small cells with radial arrangement at periphery and there is an infiltration of epidermis into dermis
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diagnosis: basal cell carcinoma
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what type of skin cancer responds to imiquod (Aldara)
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Superficial type Basal Cell carcinoma
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The most malignant melanoma is
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superficial spreading
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resection of the involved regional lymph node is required for
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congenital hairy nevus overlying axillary nodes (Brewslow 1.8mm into reticular dermis).
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Telangiectasias are
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serpiginous threadlike red lesions which blanch on diascopy
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black pt presents with pigmented streak on left thumbnail plate thats been there for several months and is growing. It is asymptomatic and irregular in width. biopsy:
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squamous cell carcinoma/acrolentigenous melanoma
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In ABCDE for melanoma B stands for
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Border
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Ship captain has multiple oval to round brown macules on back of forearms and dorsum of hands. These are called
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Solar lentigines
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Pt presents with dome-shaped reddish, smooth, firm nodule w/ central crust. Lesion is on forehead, is slowly enlarging and there's extensive sun damage around the lesion. Diagnosis:
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Squamous cell carcinoma
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Pt presents with waxy, white to yellow lesion on left cheek x 1 year. PE shows sclerotic plaque w indistinct margins and telangiectasias. Diagnosis:
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Morpheaform Basal cell carcinoma
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Granulation tissue
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capillaries and inflammatory cells
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clean wound
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less than 100,000 organisms per gram of tissue
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inflammatory phase of wound healing
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no collagen but macrophages and PMN's present
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burns are classified by
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depth of injury
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partial-thickness burn wounds
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vary in amount of pain
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most common bacterias infecting burn wounds are
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Staph and Strep
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initiation of tx for burn patient is to
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first stop the burning process
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diabetes mellitus increases
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incidence for wound infection
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an example of contaminated wound requiring surgery is
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colon resection for ruptured diverticulum
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perioperative abx are most effective in preventing infx if given
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as close to the time of surgery as possible
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CREST syndrome is best characterized by
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calcinosis
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important SLE feature -
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false positive syphilis serology
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most common presenting feature in scleroderma (progressive systemic sclerosis):
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raynaud's phenomenon
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clinically, glucocorticoids are most likely used for
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inhibiting formation of prostaglandins
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topical glucocorticoids have the beneficial effect of
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causing atrophy of hypertrophic scars
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chemical peels are used to treat
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hyperpigmented psoriasis
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sclerotherapy is indicated for
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varicose and telangiectic veins
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best topical acne therapy is
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clindamycin
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a common and effective keratolytic agent is
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alpha-hydroxy acids (fruity acids)
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PUVA is used for
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Psoriasis
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