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28 Cards in this Set
- Front
- Back
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regular crystalline insulin
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-short acting insulin
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NPH
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-intermediate acting insulin
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PZI
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long acting insulin
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semilente
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short acting insulin
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lente
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intermediate acting insulin
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ultralente
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long-acting insulin
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lispro
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semi-synthetic rapid insulin
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aspart
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semi-synthetic rapid insulin
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glulisine
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semi-synthetic rapid insulin
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largine
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intermediate semi-synthetic insulin
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detemir
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long acting semi-synthetic insulin
-myristoylation of lysin so increased affinity for plasma proteins |
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tolbutamide
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-short acting sulfonylurea
-will induce hypoglycemia |
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chlorpropramide
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-long acting sulfonylurea
-will induce hypoglycemia |
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glipizide
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-2nd gen sulfonylurea
-will induce hypoglycemia |
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glyburide
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2nd gen sulfonylurea
-will induce hypoglycemia |
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glimepiride
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-2nd generation sulfonylureas
-intermediate acting -will induce hypoglycemia |
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repaglinide
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short acting glitinide
-enhances insulin release and potentiates effects -CAN induce hypoglycemia |
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nateglinide
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rapid acting glitinide
-enhances insulin release and potentiates effects -CAN induce hypoglycemia |
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metformin
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decreases gluconeogenesis, increases glucose uptake and glycolysis
-will NOT induce hypoglycemia |
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rosiglitazone
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-a thiazolidinediones
-increases insulin sensitivity via increase in GLUT and increase in FA metabolism -will NOT induce hypoglycemia |
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pioglitazone
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-a thiazolidinediones
-increases insulin sensitivity via increase in GLUT and increase in FA metabolism -will NOT induce hypoglycemia |
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acarbose
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glucosidase inhibitor
-decreases carb absorption by inhibiting alpha-glucosidase -GI side effects |
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miglitol
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glucosidase inhibitor
-decreases carb absorption by inhibiting alpha-glucosidase -GI side effects |
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exenatide
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GLP-IR agonist, increases insulin release, decreases appetite
-an incretin mimetic |
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sitagliptin
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inhibits DPP4 (increases incretins), weight loss, activates insulin release
-flu like side effects -incretin mimetic |
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pramlintide
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-agonist at amylin receptor = decreased glucagon
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Inducers of hypoglycemia
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-ethanol
-b-adrenergic antagonists -salicylates |
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inducers of hyperglycemia
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-epi, glucocorticoids, oral contraceptives
-clonidine, Ca++ channel blockers, thiazide diuretics |
