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8 Cards in this Set
- Front
- Back
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What is innate(non-specific) immunity?
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First line barrier, which is not improved by repeated antigen exposure. It compromises of physical barriers (skin), microbicidal factors (lysosomes), phagocytic cells (neutrophils). It is very effective at prevention invasion or growth
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What is adaptive (specific) immunity?
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Activation of one or more classes of lymphocytes, is improved by repeated exposure to the specific antigen as it has immunological memory
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What happens when a neutrophil comes in contact with a pathogen?
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The neutrophil will adhere to it, folds its membrane around the pathogen taking it into a vesicle (phagosome) within its cytoplasm. Will then fuse with a lysosome and the digestive enzymes will destroy the pathogen.
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What is complement?
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A series of 20 blood proteins that can diffuse out of the blood stream into the tissue spaces and act to limit infection
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What occurs when the complement system is activated?
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Chemotaxis (attraction of neutrophils)
Diapedis (change in vascular permeability of blood vessels to make it easier for immune cells to move through) Opsonisation (coating of foreign antigen with antibodies) |
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What is phagocytosis promoted by?
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Common bacterial cell wall component
C3b complement component (complement-mediated opsonisation) Fc region of antibodies (immune-complex opsonisation) |
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What do virus-infected cells release?
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Glycoproteins called interferons
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What do interferons do?
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Bind to nearby uninfected cells and induce changes in them so they become transiently resistant to infection.
Activate NK cells to kill virus-infected cells |
