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12 Cards in this Set
- Front
- Back
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Inhalant Effects/Mechanism
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Potentiation of GABAa receptors
Place pref - inc DA firing in VTA |
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Inhalant Health Effects
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Sudden sniffing death syndrom
Myelin Damange Liver and Kidney damage |
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3 Types of steroids in Gonads
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Estrogens
Progestins Androgens (testosterone) |
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Anabolic Steroids
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Testosterone derivative w/ increased Anabolic/androgenic ratio of up to 3
(nandrolone, THG) |
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Reinforcing Properties of Steroids
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No self administration
Positive place preference results (effects take too long for self admin to be effective) |
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Genetic Androgen Action
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Linkage w androgen receptor and transcriptional activation in the nucleus
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Health Effects of Steroids
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Possible withdrawal (dependence?)
Cardio - hypertension etc Liver - Jaundice, tumors, peliosis hepatis Irritability androgenic effects |
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GHB resembles what NT
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GABA
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Another date rape drug
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rohypnol
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GHB treats what?
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Narcolepsy
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Mechanism of GHB
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GABA b activation or potentiation
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GHB tolerance
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mice become tolerant to motor suppressant effects
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