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20 Cards in this Set
- Front
- Back
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T/F Stress and NSAIDs may induce flair in IBD
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true
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T/F Crohn's disease is primarily found in the proximal ileum
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False, primarily found in terminal ileum
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Crohn's disease pathology findings
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creeping fat
noncaseating granulomas involves entire wall - transumural acute cryptitis skip leasions cobblestone appearance due to ulcers fistulas |
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T/F crohn's disease incidence peaks only in the 2-3rd decades of life
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False; bimodal distrubution - 2nd-3rd decades AND 6-7th decades
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Symptoms of colonic involvment from crohn's
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diarrhea
lower abdominal cramp msucous and blood in stool |
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symptoms of rectal involvement in crohn's disease
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tenesmus
pain to tailbone frequent small bowel movement with bloody mucous |
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abdominal location of pain and its associated organ
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RLQ = terminal ilium
near umbilicus = small bowel stomach/duodenum - epigastric region |
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symptoms of crohn's disease on terminal ileum
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pain in RLQ
obstructive features - nausea, vomit, diarrhea, then constipation malabsorption of B12 malabsorption of bile salts - oxalate kidney stones noise in belly - water siphon |
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symptoms of small bowel involvement in crohn's disease
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pain to umbilical area
obstructive feature malabsorption of nutrients peritoneal signs |
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symptoms of stomach/duodenal in crohn's disease
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mimics ulcer
pain in epigastric area |
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symptoms of esophageal involvment in crohn's disease
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sternal pain
dysphagia |
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extraintestinal manifestation of crohn disease
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polyarthrotis
erythema nodosum uveitis oral ulcers abscess fistula inactive disease: ankylosing spondylitis clubbing sclerosing cholangitis kidney stone and gallstone colon cancer |
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blood test for crohn's
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OmpC
ASCA - ansti-saccharomyces ccerevisiae |
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T/F onset of UC is between ages of 20-25
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true
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Ulcerative Colitis Pathology findings
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mucosal inflammation
involves rectum and expands to proximal colon in retrograde, fashion continuous inflammation - no skip lesions no granulomas acute cryptitis effect on colon only pseudopolyps toxic megacolon |
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ulcerative colitis clinical
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relapsing diarrhea
# of bowel movements indicate severity tenesmus paradoxical constipation colon cancer infections - salmonella and c-dff |
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T/F Ulcerative colitis extraintestinal manifestation include abscesses and fistulas
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FALSE - crohn's only has abscesses and fistulas
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Ulcerative colitis diagnosis
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colonscopy
pANCA |
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Treatment for IBD
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STOP ALL ASPRIN AND NSAIDS
first level: 5-ASA compounds - sulfasalazine 2nd level: steroids 3rd level: immune modulators - 6mercaptopurine, or remicade (antibody against TNFalpha) |
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T/F ulcerative colitis treatment includes discontinuing of smoking
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FALSE, its true for crohn's but not for UC
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