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24 Cards in this Set
- Front
- Back
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Signs and Symptoms
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P-ain
R-edness I-mpaired function S-weating H-eat |
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Hyperemia
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flooding of capillary network with arterial blood
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Congestion
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Blood flow in dilated capillaries and venules is slow
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Vessel Wall Changes
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changes of permeability of capillary walls in response to inflammation
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Effects of mediators of inflammation
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vasodilation, vasoconstriction, alteration of vascular permeability, activation of inflammatory cells, chemotaxis, cytoxicity, degradation of tissues, fever, pain
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Histamine and effects
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Released from platelets, mast cells, basophils, increases blood vessel permeability... fluids and cells exit into interstitial spaces, vasodilation, effects are quick but last less than 30 min
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Bradykinin
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- plasma protein- similar to histamine but slower, amplifies and sustains response to injury, PAIN
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Complement system
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several proteins activated in a cascade - activated by antibody complexes, bacterial toxins, fungi, snake venom, etc. they all promote inflammation
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Emigration of Leukocytes
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Diapedesis - active movement of WBCs through capillary wall into tissues
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Transudation
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Leakage of fluid rich in proteins ( TRANSUDATE) from capillaries into interstitial space = EDEMA
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Exudation
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emigration (diapedesis) of cells and fluid through capillary wall - EXUDATE - contains inflammatory cells (WBCS) and much more protein than transudate
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Phagocytosis
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dominated by pus formation = purulent or suppurative
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First cells to appear in acute 1
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neutrophils
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Precursors of mast cells
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basophils
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Platelets
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fragments of large multinucleated cells(megakaryocytes) - release of hsitamine, promote formation of connective tissues, maine function = hemostasis
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Purulent inflammation
ABSCESS |
Localized collection of pus within an organ or tissue
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EMPYEMA
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accumulation of pus in preformed cavity
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ULCER
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defect involving epithelium, may extend into deeper connective tissue
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Pseudo membranous inflammation
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ulcerative inflammation + fibrin-purulent exudation
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Mitotic cells
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continuosly dividing = labile cells
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Facultative mitotic cells
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= stable cells - do not divide regularly, can be stimulated to divide, parenchymal organs
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Postmitotic cells
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(nondividing cells) = permanent cells - neurons, myocardial cells, repair by fibrous scarring
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Substances needed for collagen formation
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Vit C, zinc, protein
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Vascularized CT
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granulation tissue formation
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