Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/7

Click to flip

7 Cards in this Set

  • Front
  • Back
What is Infective endocarditis?
colonization of heart valves w/ microbiologic organisms

leading to

formation of friable, infected vegetations

and

frequently valve injury.
Pathogenesis
Bacteremia is a prerequisite for IE. They may derive from an infection elsewhere in the body; IV drug abuse; dental or surgical procedures; or micro-injuries to gut, urinary tract, oropharynx, or skin.
Predisposing factors
 Cardiac congenital anomalies (e.g. tight shunts, VSD, ASD)
 Previously damaged valves (e.g. rheumatic heart disease)
 Prosthetic valves
 Indwelling catheters
 Neutropenia
 Immunosuppressed states
Compx: TYPES?
Cardiac
Embolic
Renal
Cardiac compx?
Valvular insuff.
Stenosis
CF

Myocardial ring abscess +/- aortic/IV spetum perf.
--Suppurative pericarditis

(Artificial valves) Partial dehiscence + paravalvular leak
Embolic compx?
LEFT sided lesions:
-Brain: cerebral infarct, abscess, meningitis
-Heart: MI
-Spleen: abscess
-Kidneys: abscess

RIGHT sided lesions:
-Lungs: infarct, abscess, pneumonia
Renal compx?
Embolic Infarction

Focal + diffuse GLOMERULONEPHRITIS
due to trapping of Ab-Ag complexes

--> Haematuria, albuminuria + RENAL FAILURE

Multiple abscesses esp. w/ acute Staph.