Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
13 Cards in this Set
- Front
- Back
|
Skin and soft tissue infections
uncomplicated vs complicated |
uncomplicated
- immunocompetent pts complicated occur in pts w/: - burns - DM - infected decubitus ulcers - traumatic or surgical wounds complicated usually polymicrobial |
|
|
skin and soft tissue infections
predominant cause of suppurative skin infection in the US |
MRSA
|
|
|
Skin and soft tissue infections - treatment
doc alternatives severe, less severe what not to use due to resistance CA-MRSA |
doc - vancomycin
alternatives - linezolid or daptomycin tigecycline (very broad) best reserved for pts unable to take other drugs less severe - usually CA-MRSA - clindamycin - trimethoprim/sulfamethoxazole - doxycycline don't use fluoroquinolones for either CA-MRSA or MRSA |
|
|
skin and soft tissue unlikely to be MRSA
uncomplicated treatment |
antistaphalococcal penicillin
- dicloxacillin - first generation cephalosporin - eg cephalexin - if pt requires hospitalization - same classes but IV instead of PO - nafcillin, cefazolin - clindamycin good choice for pts allergic to b-lactams |
|
|
skin and soft tissue unlikely to be MRSA
complicated treatment |
one of following as empirc monoTX
pip/taz ticarcillin/clavulanate imipenem meropenem in severely ill pts - add vanc or linezolid until MRSA is ruled out |
|
|
Bone and joint
osteomyelitis (bone infection) - common bug - common dz septic arthritis (joint infection) |
bug - S. aureus most common
DM pts commonly get foot infections that involve both bone and soft tissue and are usually polymicrobial w/both anerobic and anaerobic bacteria |
|
|
osteomyelitis
- empiric treatment joint infection |
osteomyelitis
IV antistaphylococcal penicillin (oxacillin) or first get ceph (cefazolin) joint ceftriaxone both-if MRSA - vanc or linezolid (if pt cant have vanc) |
|
|
chronic osteomyelitis (as common in DM)
|
requires surgical debridement of bone followed by 4-8 w of abx tx
well absorbed oral abx used - Bactim - metronidazole - flurorquinolones - linezolid - reversible bone marrow suppression especially w/tx > 2w |
|
|
Upper respiratory tract infections
|
- Acute sinsitis (often viral)
- AECB (often viral) - acute pharyngitis |
|
|
acute sinusitis, when bacterial is caused by which organisms
and treatment |
pneumococci
H influenzae Moraxella catarrhalis amoxicillin or amox/clavulanate -------------OR-------------------- cfuroxime axetil or defpodoxime -------------OR-------------------- flurooquinolone w/good antipneumococcal act'y like levofloxacin or moxifloxacin |
|
|
acute bacterial sinusitis ABS
when pt allergic to pen and ceph |
One of the following:
doxycycline tmp/smx axithromycin clarithromycin moderate ABS or risk factors for infection w/drug resistant s pneumoniae (eg recent abx use) - high dose amox/clav ---------OR------------ - antipneumococcal fluoroquinolone |
|
|
AECB treatment
|
same as w/ABS
|
|
|
acute pharyngitis
|
penicillin or macrolide if allergic to pen
|
