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5 Cards in this Set

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caspofungin
echinocandic systemic antifungal agent

used with refractory aspergillosis and candida esophagitis
caspofungin

mechanism of action
causing fungal cell wall lysis
competitive inhibitor fo beta (1,3) synthase
essential component of fungal cell wall synthesis

causes osmotic instability within the fungus and fungal cell wall lysis
spectrum of activity
candida spp

resistant to azoles and amphotericin B
therapeutic uses
alternative to amphotericin B

Aspergillus