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30 Cards in this Set

  • Front
  • Back
________% of children 2-11 years have dental caries.
42%
________% of the US population has gingivitis.
90%
________% of Americans have periodontitis.
50%
Dental plaque is a ________ disease involving environmental factors, systemic disease/host defense, microbial etiology, and genetic factors.
multifactorial
Teeth are exposed to over ________ bacterial species. Teeth enamel do not "shed" which allows for easy ________.

600


colonization

The ________ hypothesis states that any plaque would produce irritants and inflammation.
non-specific plaque
ANUG (Acute Necrotizing Ulcerative Gingivitis) was found to be caused by ________.
Spirochetes
A ________ is a microbially derived sessile community characterized by cells that are irreversibly attached to a substratum or interface or to each other, are embedded in a matrix of extracellular polymeric substances that they have produced, and exhibit an altered phenotype with respect to growth rate and gene transcription.
biofilm
Early colonizers include ________ and ________.

Streptococcus


Actinomyces

After co-aggregation and multiplication, there is adherence of gram-negative organisms including ________ and ________.

F. nucleatum


P. intermedia

________ are the circulatory system of biofilms.
Channels
________ is essential for colonization.
Adherence
The early biofilm (4-8 hours) has a ________ level of diversity and is mainly colonized by ________.

low


Streptococci

The young biofilm (1-2 days) has a 20% increase in ________ at healthy sites, a 15% increase in ________ and 10% increase in ________ at diseased sites.

Veillonella


Veillonella


gram-negative rods

The intermediate biofilm (5 days) has an additional 8% increase in ________ and members of the ________ complex are present.

gram-negative bacilli


orange

The climax biofilm (10 days) is characterized by increase in mass but constant cell counts. At healthy sites, there is an increase in ________ and ________. At diseased sites, there is an additional 18% increased in ________ and decreases in ________.

gram-positive rods


gram-negative cocci


gram-negative rods


cocci

As disease progresses, there are LESS cocci and ________ rods, and MORE ________ and ________ rods.

non-motile


Spirochetes


motile

Yellow complex includes the ________ genus and are associated with ________.

Streptococcus


health

Blue complex includes ________.
Actinomyces
Purple complex includes ________ and ________

V. parvulla


A. odontolyticus

Orange complex are a ________ to the red complex.
bridge
Red complex includes ________, ________, and ________.

P. gingivalis


T. forsythus


T. denticola

There is no O2 present inside the pocket. The sources of bacterial nutrition come from the ________ and ________.

periodontal tissues


blood

A. actinomycetemcomitans is usually ________ and dominates the bacterial community.
isolated
Viruses are associated with ________ and ________ complexes.

orange


red

Filifactor alocis and Parvimonas micra are most abundant in ________ patients.
localized aggressive periodontitis
Bacteria cause inflammation and destruction directly onto the tissues by: (list 5 ways)

LPS


ammonia


Volatile sulfur compounds


fatty acids


proteases

Host cells fight the bacteria by triggering an immune response releasing: (list 3)

MMPs


Cytokines (IL-1, TNF)

Prostaglandins (PGE2)

The microflora attacks the host, and the host attacks the microflora but will also create release cytokines, prostaglandins, and MMPs that will culminate with tissue and bone ________.
destruction
________, ________, and ________ factors also play a role in the destruction of tissue and bone.

Environmental


acquired


genetic