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10 Cards in this Set

  • Front
  • Back
What are the 3 major groups of microorganisms making up the normal flora on the skin?
Diphtheroids, Staphylococci, and Yeasts

Opportunistic pathogens
Diphthroids

NORMAL FLORA
Variably shaped, non-motile

Gram-positive, low virulence

Corynebacterium and Propionibacterium genera

Non-toxin producers

Common diphthroid: Propionibacterium acnes
Staphylococci

NORMAL FLORA
Gram-positive cocci arranged in clusters.

Coagulase negative

Facultatively anaerobic

Salt tolerant

Principle species: Staphylococcus epidermis
Fungi

NORMAL FLORA
Malassezia genus

Require oily substances to grow (lipophillic)

Can cause skin conditions such as rash, dandruff, or tinea versicolor.

More common in older people.
Most hair follicle infections are caused by:
Staphylococcus aureus
S. aureus
Gram-positive cocci (spherical)

Aerobic
Virulence factors of S. aureus:
-Capsule: prevents phagocytosis
-Clumping factor: attaches the bacteria to fibrin, fibrinogen, and plastic devices
-Coagulase: blocks WBCs from coming to site by producing clots
-Hyaluronidase: breaks down hyaluronic acid component of tissue - promotes extension of infection
-Lipases: breaks down fats
-Proteases: degrades collagens and other tissue proteins
-Protein A: binds to Fc portion of antibody - inhibits phagocytosis
Bacteria that causes SSSS
S. aureus
Streptococcal impetigo
Caused by streptococcus pyogenes

Sometimes by S. aureus
Streptococcus pyogenes
Gram-positive, beta-hemolytic cocci

Group A (Group A cell wall polysaccharide)