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19 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Pen G
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Natural Beta Lactam PCN - Narrow Spectrum
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Susceptible G+ cocci, Neisseria Meningitidites, spirochetes, anaerobic clostridium perfringes. ADR: GI distress, diarrhea, allergic responses
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Pen VK
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Natural Beta Lactam PCN - Narrow Spectrum
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Oral form of Pen G. Same G+ as above, especially streptococcus
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Methicillin
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Narrow Spectrum, beta lactamase-resistant PCN
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Penicillinase producing strains of staphylococci - interstitial nephritis decreases use
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Nafcillin/Oxacillin
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Narrow Spectrum, beta lactamase-resistant PCN
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Penicillinase producing strains of staphylococci
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Cloxacillin/Dicloxacillin
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Narrow Spectrum, beta lactamase-resistant PCN
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Penicillinase producing strains of staphylococci - higher lipophilicity, most likely to see in community pharmacy
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Amoxicillin
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Semi-synthetic, aminoPCN
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Some G+ (enterococcus faecalis, streptococcus), E. coli, proteus mirabilis, salmonella, listeria monocytogenes - not beta lactamase resistant - borrelia burgdorferi
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Ampicillin
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Semi-synthetic, aminoPCN
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Some G+ (enterococcus faecalis, streptococcus), E. coli, proteus mirabilis, salmonella, listeria monocytogenes - not beta lactamase resistan
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Carbenicillin Indanyl
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Broad Spectrum PCN (pseu. aer possible, not 1st line)
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enterobacter spp.
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Ticarcillin
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Broad Spectrum PCN (pseu. aer possible, not 1st line)
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enterobacter spp., less Na than cabenicillin
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Piperacillin
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Broad Spectrum PCN (ureidopenicillin- mezlocillin also in this group)
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Best pseudonomal activity, not for G+
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Ampicillin/Sulbactam (NO AB activity in sulbactam)
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Semisynthetic PCN with beta lactamase inhibitor
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bacteroides fragilis, moraxella catarrhalis, hemophilus influenzae
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Amoxicillin/Clavulanate (NO AB activity in clavulanate) - Augmentin
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Semisynthetic PCN with beta lactamase inhibitor
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moraxella catarrhalis, hemophilus influenzae
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Ticarcillin/clavulanate (NO AB activity in clavulanate)
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Broad spectrum PCN with beta lactamase inhibitor
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No DOC, increase dose to be as effective in other bacteria
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Piperacillin/tazobactam
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Broad spectrum PCN with beta lactamase inhibitor
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bacteroides fragilis, pseudomonas aeruginosa
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Aztreonam
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Monobactam
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NO DOC, aerobic G-, no + or anaerobic, very beta lactamase resistant, alternative to aminoglycosides
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Doripenem
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broad spectrum Carbapenems
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complicated intraabdominal ID, complicated UTI, pyelonephritis. bacteroides fragilis, citro/enterobacter spp., pseudomonas aeruginosa. ADR: N/D, rash, no inhibition of p450,only IV
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Imipenem/cilastin
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broad spectrum carbapenem/dihydropeptidase inhibitor
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No protection from beta lactamase
Bacteroides fragilis, citrobacter spp., enterobacter spp., some G+ but not DOC |
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Meropenem
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broad spectrum carbapenem
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No protection from beta lactamase
Bacteroides fragilis, citrobacter spp., enterobacter spp., some G+ but not DOC |
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Ertapenem
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broad spectrum carbapenems
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good beta lactamase stability, bacteroides fragilis, citro/enterobacter spp., serratia, salmonella, SSSI (G+), not if severe PCN allergy, NVD, CNS AE, no use in children
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