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20 Cards in this Set
- Front
- Back
What does the typical CSF fluid of a patient with acute bacterial meningitis show?
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• 500-10,000 cells/µL (mostly neutrophils)
• glucose < 40 mg/dl • protein > 150 mg/dl |
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What types of bacterial meningitis presents without a predominance of neutrophils?
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• meningitis precededaby antimicrobial therapy
• Listeria monocytogenes meningitis • Tuberculous meningitis • Syphilitic meningitis |
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What is pleocytosis?
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an increase in WBCs (or RBCs) in a bodily fluid
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What are manifestations of neurosyphilis?
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• stroke-like presentation (general paresis)
• tabes dorsalis • meningitis presentation (meningovascular) |
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What is the treatment for H. Flu meningitis?
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• Cefotaxime
OR • Ceftriaxone |
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What is the treatment for menigitis caused by Listeria monocytogenes?
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Ampicillin for a minimum of 15-21 days (with an aminoglycoside for the first 7 days)
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What is the most frequent cause of aseptic meningitis?
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Viral infection (97% due to enteroviruses)
• coxsackie virus B • echovirus • mumps • Herpes Simplex virus • Leptospira |
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What viral cause of aseptic meningitis can cause temporal lobe manifestations?
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herpes simplex virus
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Patients with this viral cause of meningitis may develop parotitis or orchitis
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Mumps
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What are theoretical causes of meningeal signs (like Kernig and Brudinski signs)?
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meningeal irritation involving the spinal cord
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What are possible causative agents for subacute to chronic meningitis?
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• Coccidioides
• Cryptococcus • Histoplasma • HIV • Lyme Disease • Mycobacterium tuberculosis • Treponema pallidum |
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What is the most common fungal meningitis?
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Cryptococcal meningitis
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What is the treatment for cryptococcal meningitis?
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• Amphotericin B
OR • Fluconazole |
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What is the difference between encephalitis and encephalopathy?
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• encephalitis is an inflammation of the brain parenchyma due to infectious causes
• encephalopathy is usually due to secondary causes (ex. toxins, metabolic causes) - Wilson's disease, hepatic encephalopathy, Wernicke's |
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What is the most frequent and treatable cause of encephalitis?
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herpes simplex virus
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What are particularly omnious signs of meningitis?
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• cranial nerve palsies (CN III, IV, VI, VII, VII)
• seizures |
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What is the most common space-occupying lesion in HIV-infected patients?
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toxoplasmosis
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What is the treatment of toxiplasmosis?
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• pyrimethamine
• sulfadiazine |
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What are etiologies for a brain abscess?
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• odontogenic
• otogenic • sinusitis |
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What are signs and symptoms of a brain abscess?
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• confusion
• drowsiness • headache • seizures • signs of increased ICP • focal neurologic deficit |