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106 Cards in this Set

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Infectious disease
One in which a transmissible infectious agent invades through physical barriers such as skin or gastrointestinal mucosa and overcomes innate and adaptive immune defenses to cause injury and disease.
Endemic
The normal or expected rate of infection in a population or geographic area
Commensal
They benefit but we are not harmed
Pathogens
Those that can cause disease
Host
The infected person, plant, or animal
Parasites
Organisms that live off of the host
Microbes
Infectious agents that are usually microscopic
Prions
Mere molecules a corrupted form of normal brain protein
Viruses
Packets of nucleic acid encased in a protein coat; have no cell wall or nucleus and have no metabolism
Bacteria
Much larger than viruses in can be seen by conventional light microscopy
Gram stain
The universal standard stain
Cocci
Spherical forms of a bacteria
Bacilli
Elongated forms of bacteria
Coccobacilli
Combination of cocci and bacilli
Spirochetes
Corkscrew shape bacteria
Aerobic
Bacteria that require oxygen
Anaerobic
Bacteria that do not require oxygen
Molds
Those that grow as long, branching multicellular filaments (hyphae)
Yeast
Go as multicellular clusters of budding brown forms (spores)
Protozoa
Motile single celled nucleated organisms that are capable of reproducing within cells
Helminths
Parasitic worms
Ectoparasites
Small insect like creatures that attach to or live in the skin
Fleas ticks bedbugs lice
Virulence
The degree of harmfulness of a microbe
Tropism
A preference for a particular type of cell
Bacterial toxin
Any bacterial substance that contributes to illness
Endotoxin
Component of the cell membrane released as the organism dies
Exotoxin
Product synthesized and excreted by the bacterium
Host immunity
The cause of tissue damage
Chronic inflammation
characterized by accumulation of lymphocytes and macrophages
Cytopathic reaction
Cell death
Cytoproliferative reaction
Abnormal cell growth
Contagion
The spread of infection from 1 person to another
Community-acquired
Infection acquired outside of a hospital
nosocomial
Infection acquired in a hospital
Reservoir
A place where the pathogen exists and from which it spreads to new host
Carrier
A person or animal harboring the pathogen but suffering no obvious disease
Fomites
Inanimate materials such as door knobs, gloves, bed sheets, or handkerchiefs
Septicemia or sepsis
When blood is the main infected tissue
Incubation period
The time between invasion and appearance of signs or symptoms
Prodromal period
After the incubation period; the patient suffers from mild nonspecific symptoms
Acute phase
A time of maximum acute typical clinical signs and symptoms
Convalescence
The period in which symptoms fade
Recovery period
No symptoms are present but the patient may feel fatigued
Rhinoviruses
A family of over 100 varieties that are the cause of about half of all cases of the common cold
Rhinoviruses
A family of over 100 varieties that are the cause of about half of all cases of the common cold
Adenovirus
Usually infects the upper respiratory tract causing tonsillitis
Respiratory syncytial virus
A major cause of lower respiratory tract infections during infancy and childhood
Influenza
Properly refers to an illness caused by influenza viruses
Rotavirus
The most common cause of severe diarrhea among infants and young children
Norovirus
Causes about 90 of non-bacterial outbreaks of epidemic gastroenteritis around the world
Measles
A very highly contagious infection by the measles virus it is spread through nasal and oral secretions
Mumps
An acute contagious infection caused by the mumps virus it is characterized by painful swelling of the salivary glands usually the parotid
Rubella
A contagious virus infection by the rubella virus. May be asymptomatic or may cause a brief mild febrile illness featuring Adinopathy rash
poliomyelitis
An acute contagious infection caused by the polio virus it is spread by oral fecal contamination
Hepatitis A virus
The cause of acute viral hepatitis an epidemic form of hepatitis transmitted by oral fecal contamination
Coxsackie virus
Classed into two subtypes A & B type A infection is tropic for oral mucosa and skin type B infection is tropic for heart lungs pancreas in nervous systems in causes inflammation of those organs
Latent virus infections
Those in which the virus in noninfectious form but can periodically reactivate to cause recurrent disease in new infections
herpes simplex virus
Has two subtypes type 1 and type 2 type 1 is usually associated with oral cold sores and type 2 with genital herpes
Herpes zoster virus or varicella-zoster virus
Closely related to the herpes simplex virus the acute infection is chickenpox
Shingles
Local outcroppings of painful small blisters reactivated from the chicken pox
cytomegalovirus
A variety of herpes virus that infects blood monocytes in related cells and causes a wide array of illnesses depending on host age and immune status
Human immunodeficiency virus
infect the nucleus of T cells in uses is RNA to make DNA which it splices into host cell DNA and thereby takes over host cell metabolism
Opportunistic infections
Infections by organisms that do not cause disease in people with healthy immune systems
Productive infections
Those in which the virus persists in infectious form and continues to replicate and cause chronic injury
Hepatitis B virus and hepatitis C virus
The agents of distinctive types of chronic viral hepatitis each is associated with chronic productive scarring of the liver
Transformative infections
Those in which the virus persist in infectious form and can stimulate the transformation of normal tissue into a neoplasm
Epstein-barr virus
The agent of infectious mononucleosis a short term febrile illness of young adults. An endemic in many populations and can produce chronic infection that has been linked to the development of some non-hodgkin's lymphomas and nasopharyngeal carcinoma
Human papillomavirus
Infect skin and squamous mucosa
Kaposi sarcoma associated herpesvirus
A sluggishly malignant skin tumor that is endemic in the Mediterranean basin and Africa
Staphylococci
gram positive cocci that cause acute pyogenic infections. Grows and tight clusters and has characteristics that tend to cause localized intense inflammation.
Streptococci
Cause a wide variety of pyogenic infections of skin pharynx lungs and heart valves. Tend to grow in twisted chains into spread along surfaces in tissue planes.
Alpha hemolytic
The cause of lobar pneumonia
Beta hemolytic group A
Typically cause infection of superficial services such as pharynx or skin
Beta hemolytic group B
A major cause of neonatal pneumonia, meningitis, and sepsis, and in adults are frequent culprits in urinary tract infections.
Beta hemolytic Group D
Streptococci key are in aerobic
Diphtheria
an acute pharyngeal or skin infection caused by Corynebacterium diphtheriae, an anaerobic, gram positive bacillus pass through respiratory droplets or skin contact.
listeriosis
features bacteremia, meningitis, encephalitis, and dermatitis.
pregnant women, the elderly, in the immunodeficient are especially vulnerable.
Anthrax
A large toxin-producing, encapsulated, aerobic or anaerobic gram positive bacillus that produces spores capable of lying dormant in soil for decades or longer.
Bacillus anthracis
nocardiosis
An acute or chronic, typically disseminated infection caused by various species of nocardia
Clostridium
Gram-positive anaerobic bacilli that grow in animal feces in soil
Pseudomembranous colitis
A severe inflammatory disease of the colon
Tetanus
An acute poisoning from a neurotoxin that infects deep puncture wounds and releases a neurotoxin that causes severe muscle spasms and convulsions
Botulism
A paralytic poisoning that grows in inadequately sterilized canned foods and releases a potent neurotoxin that blocks release of acetylcholine at the neuromuscular junction.
meningococcus
An important cause of meningitis especially in young children typically carried in the throw of about 10 of the population in a spread by respiratory droplets
Meningococcal meningitis
Often occurs when people encounter new subtypes to which they are not immune, which typically occurs among children in daycare or school or in young adults living in college dormitories or military barracks
Pertussis or whooping cough
A highly communicable disease of children featuring paroxysms of severe coughing accompanied by a final inspiratory whistle
Spotted fevers
The most common of which is Rocky Mountain spotted fever occurs mainly in the Southeast United States and the Americas
Wood ticks and dog ticks are the natural reservoir in transmitted disease by skin bite
Epidemic typhus
Transmitted by body lice living on people who are in close quarters and do not change clothing regularly
Scrub typhus
Natural reservoir is rule rodents such as field mice it is transmitted to humans by the bite of a type of might commonly known as a chigger or from person to person by body lice
Lyme disease
Named after the Connecticut town where it was first discovered in the 1970 S is caused by the spirochete Borrelia burgdorferi
mycobacteria
A family of, shaped aerobic bacilli that cause chronic infection
TB
Acid fast
widely used to denote all mycobacteria
Tuberculosis Tb
A major chronic, progressive communicable disease caused by Mycobacterium tuberculosis. Most commonly in the lungs and usually features a period of latency sometimes for many years following initial infection
caseous necrosis
Semi-solid crumbly, necrotic tissue
primary TB
About 90 percent of infections are arrested in the lungs or bronchial lymph nodes by the immune system and become dormant without symptoms of disease
Primary progressive TB
the music down cannot control spread and infection immediately progresses to active disease
reactivation TB
Arises from dormant primary TB because the patient has developed a chronic, debilitating disease such as diabetes, chronic lung disease, or malignancy
ghan tubercule
Initial lung lesion
Ghon complex
Lesions in infected mediastinal lymph nodes
Miliary TB
Widespread blood-borne spread to other organs, a pathological appearance
Secondary Tb
The pattern of disease. Arises in previously infected and sensitised persons in whom the initial infection was contained by the immune system
caseating granulomas
prior immune sensitization results in acumulation of macrophages and lymphocytes around foci of tubercule bacilli and necrotic tissue
Mantoux test
A skin test for infection
Leprosy
A chronic infection caused by Mycobacterium leprae, which has tropism for the low temperature found in peripheral nerves, skin, and the oral respiratory mucous membranes
Blastomycosis, coccidioidiomycosis , cryptococcosis, histoplasmosis
Widespread in soil and dust or in areas with heavy bird droppings , acquired by inhalation, lungs are the primary site of infection
Collectively they are referred to as the deep mycoses
Aspergillosis
Fungi that are widespread in nature