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17 Cards in this Set
- Front
- Back
TORCH
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Toxoplasmosis
Other Rubella Cytomegalovirus (CMV) Herpes Simplex Virus, type 2 (HSV-2) |
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Toxoplasmosis
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protozoan parasite found in cats who hunt infected birds and mice, oocysts shed in cat feces
also in undercooked meat |
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presentation of toxoplasmosis
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mild flu-like symptoms but transplacental transmission can occur
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effects of toxoplasmosis
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1st trimester infection frequently results in abortion
infected infant may be symptom free, or may result in stillbirth or with: retardation, chorioretinitis, encephalitis, microcephaly, jaundice, fever |
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prevention of toxoplasmosis
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avoid eating undercooked meats and exposure to litter
check titer of inside cat-treat with spiramycin |
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Rubella
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virus crosses placenta and can result in miscarriage or defects
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Congenital rubella syndrome
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eye lesions
cateracts glaucoma heart defects cns defects auditory defects IUGR thrombocytopenia hepatosplenomegaly |
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prevention of rubella
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screen for adequate titer in 1st trimester
vaccinate after delivery |
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Cytomegalovirus
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herpes virus family
mono-like symptoms most common congenitally and perinatally acquired viral disease and most important cause of metal retardation |
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Risk of CMV to fetus
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IUGR
microcephaly seisures hepatosplenomegaly cerabral palsy chorioretinitis jaundice |
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transmission of CMV
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transplacental, respiratory
contact with infected body fluids breast milk urine feces banked blood |
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activation of herpes virus
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stress
uv light fever trauma |
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herpes simplex virus, type 2
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genital
primary infection in adults characterized by multiple painful lesions fever, chills, malaise, and severe dysuria |
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% of transmission of herpes virus
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40-60% with active primary infection
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viremia
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viruses enter the bloodstream and hence have access to the rest of the body
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transplacental transmission
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if it occurs early in gestation-->fetal heart demise and miscarriage
if it occurs later in pregnancy-->IUGR, PTL, MR, microcephaly |
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management of herpes virus
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vag delivery if absence of active genital lesions
CS if active lesions Acyclovir-suppresive therapy to decrease risk of transmission |