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44 Cards in this Set
- Front
- Back
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Fetal Effect: Varicella Zoster
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-Chorioretinitis
-Cerebral corticalatrophy -Hydronephrosis -Cutaneous and bony leg defects (scars) -Microcephaly |
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Maternal Effect: Varicella Zoster
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Pneumonitis
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Treatment: Varicella Zoster
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-Immunoglobulin within 96 hours of exposure
-C-section for active lesions |
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Prophylaxis: Varicella Zoster
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Vaccination during pregnancy is not recommended
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Fetal Effect: Orthomyxoviridae
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- Neural tube defects
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Maternal Effect: Orthomyxoviridae
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- Pneumonia
- Death |
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Prophylaxis: Orthomyxoviridae
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- Vaccine during pregnancy is recommended for women with chronic underlying disease or frequent exposure
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Treatment: Orthomyxoviridae
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Amantadine within 48 hours of onset of symptoms in non-immunized, high-risk patients
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Fetal Effects: Parvovirus B19
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- Abortion
- Death - Congenital anomalies - Hydrops fetalis |
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Maternal effects: Parvovirus B19
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Viremia --> Slapped cheek appearance
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Treatment: Parvovirus B19
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With + serology -->Ultrasound --> if + hydrops --> Consider transfusion
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Fetal Effects: Rubella
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- Cataracts/glaucoma
- Patent ductus arteriosus - Deafness - Mental retardation |
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Prophylaxis: Rubella
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Vaccination (attenuated live virus) of the non- pregnant female
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Treatment: Rubella
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Consider therapeutic abortion, depending on time of exposure during pregnancy.
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Maternal Effects: Hepatitis B
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Range from mild liver disfunction to death
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Prophylaxis: Hepatitis B
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Maternal screening early in pregnancy. Maternal HbsAg positive is high risk of transmitting to fetus. If mother is positive, give neonate HepB IgG at birth, 3 months, and 6 months.
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Fetal Effects: Cytomegalovirus
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- Hepatosplenomegaly
- Thrombocytopenia - Microcephaly - Intracranial calcifications - Chorioretinitis - Mental retardation - Jaundice |
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Maternal Effect: Cytomegalovirus
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Mononucleosis-like syndrome
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Treatment: Cytomegalovirus
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No known treatment
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Fetal Effects: Group B
Streptococcus (Streptococcus agalactiae) |
- Preterm labor
- Premature rupture of membranes - Ophthalmia neonatorum - Sepsis - Meningitis→ neurologic sequelae in survivors |
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Maternal Effects: Group B
Streptococcus (Streptococcus agalactiae) |
- Chorioamnionitis
- Puerperal sepsis - Mastitis - Osteomyelitis |
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Prophylaxis: Group B
Streptococcus (Streptococcus agalactiae) |
Intrapartum maternal penicillin G in women with + cultures at 35–37 wks’ GA
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Treatment: Group B
Streptococcus (Streptococcus agalactiae) |
Neonatal penicillin G IM in the delivery room (there is no universal treatment)
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Fetal Effects: Salmonella
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Death
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Maternal Effects: Salmonella
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- Enteritis
- Bacteremia |
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Treatment: Salmonella
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- IV rehydration
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Fetal Effects: Borrelia burgdorferi
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- Congenital infection
- Death - Preterm labor - Rash |
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Maternal Effect: Borrelia burgdorferi
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- Erythema migrans
- Disseminated infection - Meningitis - Carditis - Arthritis |
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Treatment: Borrelia burgdorferi
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Oral amoxicillin or penicillin
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Fetal Effect: Primary and secondary syphilis
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- Hepatosplenomegaly
- Lymphadenopathy - Hemolysis |
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Fetal Effects: Chlamydia trachomatis
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- Conjunctivitis
- Pneumonia |
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Prophylaxis: Chlamydia trachomatis
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Screen early in pregnacy
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Treatment: Chlamydia trachomatis
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Erythromycin or azithromycin
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Fetal Effects: Neisseria gonorrhoeae
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- Conjunctivitis
- Otitis externa - Pharyngitis |
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Prophylaxis: Neisseria gonorrhoeae
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Screen early in pregnancy
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Treatment: Neisseria gonorrhoeae
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Penicillin or ceftriaxone
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Fetal Effect: Toxoplasma gondii
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- Hydrocephaly/microcephaly
- Hepatosplenomegaly - Seizures - Intracranial calcifications - Chorioretinitis - Mental retardation |
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Treatment: Toxoplasma gondii
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Spiramycin (macrolide antibiotic)
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Viruses with transplacental spread:
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Varicella-zoster
Coxsackie virus Parvovirus Rubella Cytomegalovirus HIV |
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Bacteria with transplacental spread:
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Listeria
Syphilis |
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Protozoan with transplacental spread:
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Toxoplasmosis
Malaria |
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Infections that can ascend into the uterus:
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HSV
Group B strep Coliforms |
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Viruses that spread intrapartum:
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HSV
Papilloma virus HIV HBV |
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Bacteria that spread intrapartum:
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Gonorrhea
Chlamydia GBS TB |
