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44 Cards in this Set

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Fetal Effect: Varicella Zoster
-Chorioretinitis
-Cerebral corticalatrophy
-Hydronephrosis
-Cutaneous and bony leg
defects (scars)
-Microcephaly
Maternal Effect: Varicella Zoster
Pneumonitis
Treatment: Varicella Zoster
-Immunoglobulin within 96 hours of exposure
-C-section for active lesions
Prophylaxis: Varicella Zoster
Vaccination during pregnancy is not recommended
Fetal Effect: Orthomyxoviridae
- Neural tube defects
Maternal Effect: Orthomyxoviridae
- Pneumonia
- Death
Prophylaxis: Orthomyxoviridae
- Vaccine during pregnancy is recommended for women with chronic underlying disease or frequent exposure
Treatment: Orthomyxoviridae
Amantadine within 48 hours of onset of symptoms in non-immunized, high-risk patients
Fetal Effects: Parvovirus B19
- Abortion
- Death
- Congenital anomalies
- Hydrops fetalis
Maternal effects: Parvovirus B19
Viremia --> Slapped cheek appearance
Treatment: Parvovirus B19
With + serology -->Ultrasound --> if + hydrops --> Consider transfusion
Fetal Effects: Rubella
- Cataracts/glaucoma
- Patent ductus arteriosus
- Deafness
- Mental retardation
Prophylaxis: Rubella
Vaccination (attenuated live virus) of the non- pregnant female
Treatment: Rubella
Consider therapeutic abortion, depending on time of exposure during pregnancy.
Maternal Effects: Hepatitis B
Range from mild liver disfunction to death
Prophylaxis: Hepatitis B
Maternal screening early in pregnancy. Maternal HbsAg positive is high risk of transmitting to fetus. If mother is positive, give neonate HepB IgG at birth, 3 months, and 6 months.
Fetal Effects: Cytomegalovirus
- Hepatosplenomegaly
- Thrombocytopenia
- Microcephaly
- Intracranial calcifications
- Chorioretinitis
- Mental retardation
- Jaundice
Maternal Effect: Cytomegalovirus
Mononucleosis-like syndrome
Treatment: Cytomegalovirus
No known treatment
Fetal Effects: Group B
Streptococcus (Streptococcus agalactiae)
- Preterm labor
- Premature rupture of membranes
- Ophthalmia neonatorum
- Sepsis
- Meningitis→ neurologic sequelae in survivors
Maternal Effects: Group B
Streptococcus (Streptococcus agalactiae)
- Chorioamnionitis
- Puerperal sepsis
- Mastitis
- Osteomyelitis
Prophylaxis: Group B
Streptococcus (Streptococcus agalactiae)
Intrapartum maternal penicillin G in women with + cultures at 35–37 wks’ GA
Treatment: Group B
Streptococcus (Streptococcus agalactiae)
Neonatal penicillin G IM in the delivery room (there is no universal treatment)
Fetal Effects: Salmonella
Death
Maternal Effects: Salmonella
- Enteritis
- Bacteremia
Treatment: Salmonella
- IV rehydration
Fetal Effects: Borrelia burgdorferi
- Congenital infection
- Death
- Preterm labor
- Rash
Maternal Effect: Borrelia burgdorferi
- Erythema migrans
- Disseminated infection
- Meningitis
- Carditis
- Arthritis
Treatment: Borrelia burgdorferi
Oral amoxicillin or penicillin
Fetal Effect: Primary and secondary syphilis
- Hepatosplenomegaly
- Lymphadenopathy
- Hemolysis
Fetal Effects: Chlamydia trachomatis
- Conjunctivitis
- Pneumonia
Prophylaxis: Chlamydia trachomatis
Screen early in pregnacy
Treatment: Chlamydia trachomatis
Erythromycin or azithromycin
Fetal Effects: Neisseria gonorrhoeae
- Conjunctivitis
- Otitis externa
- Pharyngitis
Prophylaxis: Neisseria gonorrhoeae
Screen early in pregnancy
Treatment: Neisseria gonorrhoeae
Penicillin or ceftriaxone
Fetal Effect: Toxoplasma gondii
- Hydrocephaly/microcephaly
- Hepatosplenomegaly
- Seizures
- Intracranial calcifications
- Chorioretinitis
- Mental retardation
Treatment: Toxoplasma gondii
Spiramycin (macrolide antibiotic)
Viruses with transplacental spread:
Varicella-zoster
Coxsackie virus
Parvovirus
Rubella
Cytomegalovirus
HIV
Bacteria with transplacental spread:
Listeria
Syphilis
Protozoan with transplacental spread:
Toxoplasmosis
Malaria
Infections that can ascend into the uterus:
HSV
Group B strep
Coliforms
Viruses that spread intrapartum:
HSV
Papilloma virus
HIV
HBV
Bacteria that spread intrapartum:
Gonorrhea
Chlamydia
GBS
TB