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28 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Benzylpenecillin is effective against which bacteria? |
Streptococcal, pneumococcal, gonococcal, diphtheria, anthrax, has-gangerene, and leptospirosiscan benz |
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Can benzylpenecillin be given orally? |
It is inactivated by gastric acid and absorption in GI is low, so it must be given by Injection. |
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What is preferred first line for tetanus |
Metronidazole |
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Early suphillus and late late syphillus is treated by? |
Benzanthine benzylpenecillin injection |
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Difference between benzylpenecillin and phenoxymethyloenecillin |
Phenoxy is acid stable so can be given orally Avoid in serious because absorption can not be predicted and plasma levels |
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Which penecillin is not inactivated by staphylococci? So can be given to oenecillin resistant staphylococci? |
Flouxacin -acid stable, oral and IV |
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Which penicillin can be used in gram negative bacteria that produce beta lactamase enzymes- |
Temocillin but not active against pseudomonas aeruginosa or acinenotobactor |
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Penecillin that works well when cephalsporin resistant to and bet lactamase producing? |
Temocillin |
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Broad spec penecillin? |
Ampicillin, Amoxicillin Co-amoxiclav |
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Ampicillin pro and cons |
Works against gram negative and positive but easily broken down by beta lactamase |
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When shouldn’t you recommend ampicillin |
E. coli All staphylococci Staphylococcus aerus
St |
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The presence of food decreases the absorption of? |
Ampicillin as half the dose is only absorbed normally anyway, food reduces it further |
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Maculapapor rashes occur with |
Ampicillin but not related to penecillin allergy |
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Which patients are likely to get a macropapular rash with the use of ampicillin |
Cytomegalovirus and Lyme disease patients |
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Co amoxiclav should be used for? |
Staphylococcus aureus E. coli H influenzae |
Beta lactamase producing bacteria |
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2 antispseudomal penecillin? |
Piperecillin Ticarcillin |
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Antipsedomal lenecillins used for? |
Gram positive and negative Against psedomonas Treatment is septacemina Hospital acquired pneumonia complicated uti Skin infection
Skin infection |
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For severe pseudomonas infection you should recommend |
Piperacillin/tazarcillin and an aminoglycosylide |
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Main side effect of penecillin |
Diarohea common more with broad |
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A small rash that develops 72hours after pencillin use, is that an allergic response? |
No, and treatment shouldn’t be with held |
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Who is at risk of developing anaphylaxis reaction |
Patients with atopic condition eh eczema asthma and hay fever |
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Which penecillin can lead to hyponatraemia in high doses |
Piperacillin and ticaracillin |
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Piperacillin In pregnancy |
Only if benefits outweigh the risk, ticaracillin can be used |
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Can you give an intrathecal injection of benzylpenecillin |
Not recommended |
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Which penecillin can lead to a false positive test on urinary glucose when looking for reducing substance |
Phenoxymethypenecillin |
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When should ampicillin be taken |
At least 30mins before food |
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H |
H |
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Which penicillins are penecillenase resistant penicillins |
Fluoxacin and temocillin |
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