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27 Cards in this Set

  • Front
  • Back

Physical Incompatibilities

Insolubility/Immiscibility


Liquefaction


Polymorphism


Sorption


Volatilization


Water Loss

Insolubility/Immiscibility

Salting out


Temperature change

Examples of Endothermic reaction

KI and boric acid (dissolved in hot water)

Examples of Exothermic reaction

Ca(OH)2 and Mg(OH)2 (dissolved in cold water)

Eutectic compounds

Phenol


Menthol


Thymol Camphor

Eutectic mixtures

Lidocaine + Prilocaine (Emla®️)


Camphor + Menthol (Liniments)

Liquefaction

Eutexia


Hygroscopic


Deliquescent


Efflorescent

Cubic

Sodium chloride

Monoclinic

Sucrose

Triclinic

Boric acid

Tetragonal

Urea

Rhombic

Iodine

Hexagonal

Iodoform

Pentration into capillaries

Absorption

Surface phenomenon

Adsorption

Example of substances that undergo volatilization

Volatile oils


Alcohol


Phenol


Esters


Ketones

Result of water loss of ointments

Crumbling

Result of water loss of emulsions

Cracking

Result of water loss of gels

Synerensis

Chemical Incompatibility

REDOX


ACID-BASE REACTION


HYDROLYSIS


PHOTOCHEMICAL DEGRADATION


ISOMERISM


CEMENTATION


GELATINIZATION

Result of oxidation of Epinephrine

Pink discoloration

Result of the oxidation of vitamin C

Brown discoloration

Acid base reactions

Precipitation


Evolution of Gas


Formation of Color

Visible result of the hydrolysis of Aspirin

Vinegar like odor

Drugs that undergo photodegradation

Na nitroprusside


Nifedipine


Riboflavin

S-omeprazole is also known as

Esomeprazole (purified form)

Racemic mixture of Thalidomide

S-Thalidomide: teratogenic


R-Thalidomide: sedation/anti-morning sickness