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10 Cards in this Set
- Front
- Back
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Nuclear remnants of DNAPositive ( + ) with feulgen rxn ( reaction ) Coarse densely stained purple granules , eccentrically located on periphery of membrane Saang sakit siya nakikita? Megaloblastic Anemia Severe Hemolytic process Thalassemia Accelerated erythropoiesis
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-HOWELL- JOLLY BODIES |
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Precipitated , denatured hemoglobin Cannot be seen in wrights stain -(Supravital staining- meaning kinakapitan ay mga buhay na cells ) Deep purple irregularly shaped inclusionsSaang sakit siya nakikita? G 6PD -def unstable hemoglobin Hereditary defect in HMP (HEXOSE MONOPHOSPHATE PATHWAY) / SHUNT Favism Drug induced Splenectomized patients Thalassemia |
Heinz bodies |
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(If coarse ang BS , that is lead Poisoning, but if fine ang BS, it can be seen in increase red cell production ) Dark blue granues Punctate of basophilia Precipitation of ribosomes and RNA Saang sakit siya nakikita? Lead poisoning - We have this so called PICA ( eating inanimate like soil- term as geophigia) Note: The PICA in children is associated with lead poisoning/ plumbism The PICA in adult , it’s associated with IDA Pyrimidine 5- nucleotidase deficiency Heavy metal poisoning Thalassemia
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-Basophilic stipplings |
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(can be seen on periphery- its only difference with basophilic stripplings) (GILID GILID UNLIKE BASO THAT USUALLY COVERS THE WHOLE CELL) (another is that BD is distributed within th cell ) Basophilic inclusions that aggregate in small clusters near periphery with wright’s stain Saang sakit siya nakikita? (usually on unused iron deposits) Sideroblastic Anemia MDS Thalassemia Hemolytic anemia Dyserythropoieis
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-Pappenheimer bodies |
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Rings , loops, figure of eight, red to purple Remnant of microtubes of mitotic spindle Saang sakit siya nakikita? Dyserythropoiesis Megaloblastic Anemia Severe Anemia
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-Cabot ring |
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NEEDING SUPRAVITAL STAINS M (Young RBC’S before it become fully mature) - we use NMB( new methylene Blue )
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Reticulocytes |
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Supravital stains Crystal Violet
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Heinz Bodies - |
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Supravital stains - BCB ( Brilliant Cresyl Blue ) |
Hemoglobin H |
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-Clumping of RBC Saang sakit siya nakikita? Cold agglutinins/ PAP ( Primary Atypical Pneumonia) - which is also known as walking Pneumonia AIHA
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Auto Agglutination |
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RBC in stack of coins arrangementIncrease plasma GlobulinsIncrease ESR Saang sakit siya nakikita? MM (multiple myeloma)- ploriferation of Ig produced by plasma cells Waldenstrom’s macroglobulinemia
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Rouleaux |
