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22 Cards in this Set
- Front
- Back
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secreted by macrophages, causes acute inflammation
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IL-1
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induces chemokine production to recruit leukocytes
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IL-1
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activates endothelium to express adhesion molecules
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IL-1
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an endogenous pyrogen
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IL-1
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secreted by Th cells, stimulates growth of helper and cytotoxic Ts
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IL-2
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Secreted by activated T-cells. supports growth and differentiation of bone marrow stem cells.
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IL-3
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has similar function to GM-CSF
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IL-3
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Secreted by Th2. promotes growth of B-cells
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IL-4 and IL-5
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enhances class switching of to IgE and IgG
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IL-4
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Enhances class switching to IgA
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IL-5
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secreted by Th cells and macrophages
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IL-6
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stimulates production of acute-phase reactants and immunoglobulins
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IL-6
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secreted by macrophages, acts as a major chemotactic factor for neutrophils
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IL-8
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Secreted by regulatory T-cells
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IL-10
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Inhibits action of activated t-cells
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IL-10
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Activates Th2 and inhibits Th-1
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IL-10
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Secreted by B cells and macrophages.
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IL-12
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Activates NK and Th1 cells
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IL-12
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Secreted by Th1 cells
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IFN gamma
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Stimulates macrophages, activates Th1 and inhibits Th2
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IFN gamma
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Secreted by macrophages. mediates septic shock
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TNF
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Causes leukocyte recruitment, vascular leak
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TNF
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