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6 Cards in this Set
- Front
- Back
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immune response in RA |
autoimmune with antigen-presenting cell recognizing self antigens. through T and B cells cytokines IL-1 and TNFalpha are too strong |
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steps of drugs for RA |
start with aspirin (GI bleeds) steroids (bad SE) DMARDs (mxt) other antimetabolites biologics ($$$) |
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so how do you choose waht drug? |
poor prognositics disease duration moderate/severe/advanced classes |
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What would happen if you gave a pt that had received mtx some sulfonamides? |
sulfonamides would releases mtx |
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Is Leflunomide in the same ___ pathways as methotrexate? |
yes, pyrimidine |
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What does the suffix -cept mean?
What does -mab mean? -imab? -ximab? -umab? -zumab? |
fusion proteins
monoclonal antibodies chimeric: imab and ximab humanized: umab zumab |
