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24 Cards in this Set

  • Front
  • Back
what is the stem cell marker
cd34
what are three myeloid markers
cd13, cd33, myeloperoxidase
what are 3 lymphoid markers
cd10, T and B cell markers, TdT
AML MO expresses
cd13, cd33

myeloperoxidase negative - no Auer Rods
AML M1
CD13, myeloperoxidase positive

without maturation beyond myeloblast
AML M2
CD13, myeloperoxidase pos (AUER RODS!!!!!)

maturation - full range of granulocyte precurors
AML M3
Acute promyelocytic leukemia

AUER RODS!!!!

age 35-40
AML M4
CD4, CD14, CD64, Cd13, myeloperoxidase,

Acute Myelomonocytic Leukemia
AML M5
CD14, CD64, non-spec esterase, neg for myeloperoxidase
AML M7
CD41a -

Acute megakaryocytic leukemia
T cell antigens
CD 3,4,5,7,8
B cell antigens
CD 10 (CALLA), 19, 20, 23
granulocytes
CD 13, 33, 15
Monocytes
CD 11c, 14, 64
Activation marker
CD30
Blasts have
CD34
Lymphoblasts have
TdT
precursor B ALL/Lymphoblastic Lymphoma immunophenotype
TdT, CD10, CD19, CD20, CD34
what is immunophenotype for precursor T-cell lymphoblastic lymphoma
CD34, CD3, CD7, CD10+/-, TdT

may co-express CD4 and CD8
VERY UNIQUE AND ONLY IN PRECUROS THYMOCYTES
what is immunophenotype for chronic lymphocytic leukemia/small lymphocytic lymphoma
CD5, Cd19, Cd20, weak surface light chain restricion

CD10 neg. T-cell SLL uncommon
immunophenotype of follicular lymphoma
cd10+, CD19, CD22, surface light chain
what is immunophenotype of mantle cell lymphoma
CD5, CD19, Cd20, surface light chain restriction, cyclin D1

Cd10 & 23 negative
Translocation (11;14)
what is immunophenotype for diffuse large B cell lymphoma
Cd19, Cd20, surface light chain restriction

Cd5, 1 negative
30% trans either 3q27 or t(14;18)
what is immunophenotype for Burkitt Lymphoma
CD10, Cd19, Cd20, surface IgM w light chain restriction

Always have translocation involving c-MYC oncognene on chromosome 8 t(8;14), t(2;8), t(8;22)