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10 Cards in this Set
- Front
- Back
How does IL-2 therapy work
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-remove tumor specimen
-culture cells in presence of IL-2 -tumor infiltrating lymphocytes proliferate -TILs with anti-tumor activity are administered with IL-2 |
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What do colony-stimulating factors do
-2 examples |
-simulate growth of bone marrow progenitor cells
-sargramostim -filgrastim |
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What are colony-stimulating drugs used for
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-to shorten period and severity of neutropenia
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EPO
-stimulates what -used how |
-production of erythrocytes in bone marrow
-tx anemia assc with kidney failure, dialysis, cancer chemo |
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How are interferons used to tx cancer
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-alpha interferon has antiprolerative effect
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What two conditions is cyclophosphamide used for and why
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-cacner
-prevent organ rejection -blocks proliferation of B and T cells associated with immune response |
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How do corticosteroids work
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cytotoxic to T lymphocytes
-block production of IL-1 and IL-2 |
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How does cyclosporine work
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-binds to immunophilins
-inhibits T cell activation and production of cytokines |
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Which drug makes organ transplants possible
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cyclosporine
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What does Rho(D) IG work for
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-mom's with O- who have O+ babies
-protects against erythroblastosis fetalis |