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10 Cards in this Set

  • Front
  • Back
How does IL-2 therapy work
-remove tumor specimen
-culture cells in presence of IL-2
-tumor infiltrating lymphocytes proliferate
-TILs with anti-tumor activity are administered with IL-2
What do colony-stimulating factors do
-2 examples
-simulate growth of bone marrow progenitor cells
-sargramostim
-filgrastim
What are colony-stimulating drugs used for
-to shorten period and severity of neutropenia
EPO
-stimulates what
-used how
-production of erythrocytes in bone marrow
-tx anemia assc with kidney failure, dialysis, cancer chemo
How are interferons used to tx cancer
-alpha interferon has antiprolerative effect
What two conditions is cyclophosphamide used for and why
-cacner
-prevent organ rejection
-blocks proliferation of B and T cells associated with immune response
How do corticosteroids work
cytotoxic to T lymphocytes
-block production of IL-1 and IL-2
How does cyclosporine work
-binds to immunophilins
-inhibits T cell activation and production of cytokines
Which drug makes organ transplants possible
cyclosporine
What does Rho(D) IG work for
-mom's with O- who have O+ babies
-protects against erythroblastosis fetalis