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11 Cards in this Set
- Front
- Back
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Chronic Granulomatous Disease |
NADPH Oxidase deficiency |
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Leukocyte Adhesion deficiency |
Absence of CD 18 (integrin part) Omphalitis |
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Chediak-Higashi syndrome |
Degranulation defect - absent NK activity Albinism |
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Bruxton X-linked hypogammaglobinemia |
CD18- (no circulatin Bcells. Maturation stopped at Pre-B stage) Give antibiotics and gammaglobulins |
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X-linked Hyper IgM syndrome |
Deficiency of CD40L No class switching. High IgM Giv antibiotics and gammaglobulins |
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Selective IgA deficiency |
Repeated sino-pulmonary and GI infections Increased atopy Can't give gammaglobulins as body not familiar with IgA. Will launch hypersensitivity reaction. |
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Both pathways |
Recurrent meningococcal and gonococcal infections |
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Deficiency in complement regulatory proteins |
C1-INH Heriditary angioedema |
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Selective T-cell def: DiGeorge syndrome |
CD19+ CD3- (no Tcells) Failure of formation of 3rd and 4th pharyngeal pouches, thymic aplasia Facial abnormalities, hypoparathyroidism, poor Tcell response |
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MHC class 1 deficiency |
Failure of TAP1 to transport peptides to ER CD8+ def, CD4+ normal - recurrent viral inf |
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MHC Class II def |
CD4+ def. similar to SCID. No graft vs host disease as MHC II missing. |
