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20 Cards in this Set
- Front
- Back
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Edward Jenner
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Discovered that cowpox could offer protection from smallpox. Coined the term "vaccination." Considered the discoverer of immunology.
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Robert Koch
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Discovered that infectious diseases were caused by microorganisms (germ theory).
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What are the 4 types of Pathogens?
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Viruses, bacteria, fungi, parasites.
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Louis Pasteur
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Devised a vaccine against cholera by injecting chickens with the dead virus. Also developed a rabies vaccine which led to some cases of autoimmunity.
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What's the difference between the innate and the adaptive immune responses?
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Adaptive is developed over a lifetime in response to a pathogen, has high specificity, has a memory.
Innate has more general recognition, but acts much quicker. |
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Elie Metchnikoff
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Discovers that cells contribute to eliminating pathogens by white blood cells engulfing and digesting microorganisms.
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What does the word "Antigen" come from?
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Antibody generating
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lymphocytes
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Any white blood cell that recognize and target pathogenic microorganisms.
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What are the 4 functions of an immunological response?
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Recognition
Mobilize effector functions Regulation (return to baseline) Memory |
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Where do leukocytes originate?
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Bone marrow (pluripotent hematopoietic stem cells)
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What is the precursor of macrophages, granulocytes, mast cells and dedritic cells of the innate immune system?
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common myeloid progenator
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What does PAMPS stand for?
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Pathogen Associated Molecular Patterns
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What are the innate cells that eliminate pathogens by eating?
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Macrophages and Neutrophils
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What are the innate cells that eliminate pathogens by shooting?
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Neutrophils, Eosinophils, Basophils, Mast Cells, Natural Killer cells
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What are the 2 types of lymphocytes?
Where do they originate? |
B cells and T cell
B cells, bone marrow T cells, thymus |
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Killer T cells are attracted to what?
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MHC I
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Helper T cells are attracted to what?
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MHC II
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Helper T cells have which molecule to help them recognize MHC?
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CD4
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Killer T cells have which molecule to help them recognize MHC?
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CD8
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When helper T cells recognize a pathogen, what does it trigger?
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The APC to internalize the pathogen
Orchestrates immune response by recruiting and activating other types of cells. |
