Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
isograft
|
graft between genetically identical subjects
-these are accepted graft transplants |
|
allograft
|
graft between same species but different genotype
-these are rejected transplants |
|
xenograft
|
graft between subjects from different species
|
|
autochthonous tissue
|
tissue from same individual
|
|
chimera
|
an individual organism whose body contains cell populations derived from different zygotes, of the same or different species.
-host may not develop an immune response to this |
|
self-recognition
|
-differentiation of self substances from foreign substances
-can be proteins, carbohydrates, etc. -clonal deletion mechanism -sponge species example |
|
immune specificity
|
-T-cells and B-cells have a predisposed specificity to respond to a particular epitope or antigenic receptor
-each inidvidual cell can respond to only one epitope -as a population can recognize ~1 billion DIFFERENT epitopes |
|
Antigen
|
-a substance to which the immune system can react
-usually foreign (non-self) |
|
immune repertoire
|
the ability of the immune system to respond to perhaps 1 billion antigenic determinants
|
|
immune response
|
-antibody AND cell-mediated reactions to antigen
-involves B-lymphocytes, T-lymphocytes and APCs |
|
non-specific/innate immunity
|
-based on the genetic constitution of the individual
-non-specific means of clearing or removing most undesirable substances |
|
specific/adaptive immunity
|
-acquired immunity
-specific immunity attributable to the presence of antibody or reactive lymphocytes following prior exposure to an infectious agent or antigenic substance |
|
complement
|
complex biological system that covalently binds specific proteins to the microbial surface that can destroy invading microorganisms
|
|
classical complement pathway
|
triggered when antibodies bind to an organism
-initial component is C1 -activated by IgG -requires 2(less active) and IgM (more active) |
|
MHC
|
a gene complex that codes specialized receptor glycoproteins
-determines which antigens are processed and presented -control antigen processing and presentation |